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Loss","amount2New":0,"dosageForm":"","sponsorNew":"Evotec \/ Pfizer Inc","highestDevelopmentStatusID":"4","companyTruncated":"Evotec \/ Pfizer Inc"},{"orgOrder":0,"company":"Merdury Pharmaceutical","sponsor":"Health2Sync","pharmaFlowCategory":"D","therapeuticArea":"Nutrition and Weight Loss","country":"TAIWAN","productType":"Peptide","year":"2024","type":"Collaboration","leadProduct":"Semaglutide","moa":"","graph1":"Nutrition and Weight Loss","graph2":"Preclinical","graph3":"Merdury Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Nutrition & Weight Loss","amount2New":0,"dosageForm":"","sponsorNew":"Merdury Pharmaceutical \/ Health2Sync","highestDevelopmentStatusID":"4","companyTruncated":"Merdury Pharmaceutical \/ Health2Sync"},{"orgOrder":0,"company":"Biolexis Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Nutrition and Weight Loss","country":"U.S.A","productType":"Small 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Find Clinical Drug Development Pipelines & Deals | PipelineProspector

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : XW003,Undisclosed

                          Therapeutic Area : Nutrition and Weight Loss

                          Study Phase : Preclinical

                          Sponsor : Sciwind Biosciences

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

                          Details : In the terms of the agreement, Sanofi granted exclusive worldwide rights to Sciwind to develop, manufacture and commercialize Sanofi's GIP receptor agonists including XW003, for all applicable indications.

                          Product Name : XW003

                          Product Type : Peptide

                          Upfront Cash : Undisclosed

                          November 30, 2021

                          Lead Product(s) : XW003,Undisclosed

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Preclinical

                          Sponsor : Sciwind Biosciences

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

                          Sanofi Company Banner

                          02

                          BIO CEO & Investor
                          Not Confirmed
                          BIO CEO & Investor
                          Not Confirmed

                          Details : RaniPill HC (semaglutide) is an oral pill, which delivers glucagon-like peptide-1 (GLP-1) receptor agonist indicated for obesity.

                          Product Name : RaniPill HC

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          February 05, 2025

                          Lead Product(s) : Semaglutide

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          BIO CEO & Investor
                          Not Confirmed
                          BIO CEO & Investor
                          Not Confirmed

                          Details : The expanded collaboration will continue to utilize Valo's Opal Computational Platform, while Novo remains actively engaged in multiple small molecule preclinical drug discovery programs.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          January 08, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Preclinical

                          Sponsor : Novo Nordisk

                          Deal Size : $4,790.0 million

                          Deal Type : Expanded Collaboration

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                          04

                          BIO CEO & Investor
                          Not Confirmed
                          BIO CEO & Investor
                          Not Confirmed

                          Details : Under the licensing agreement, iBio will be solely responsible for the research and development, manufacturing and commercialization of IBIO-600 for obesity and cardiometabolic treatment.

                          Product Name : IBIO-600

                          Product Type : Antibody

                          Upfront Cash : $0.7 million

                          January 03, 2025

                          Lead Product(s) : IBIO-600

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Preclinical

                          Sponsor : iBio

                          Deal Size : $28.7 million

                          Deal Type : Licensing Agreement

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                          05

                          BIO CEO & Investor
                          Not Confirmed
                          BIO CEO & Investor
                          Not Confirmed

                          Details : BP1001-A works by binding directly to Grb2 mRNA, preventing its translation into the Grb2 protein. It is currently being evaluated for the treatment of obesity and related metabolic diseases.

                          Product Name : Undisclosed

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          December 19, 2024

                          Lead Product(s) : Prexigebersen

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          BIO CEO & Investor
                          Not Confirmed
                          BIO CEO & Investor
                          Not Confirmed

                          Details : ASC47 is an adipose-targeted thyroid hormone receptor beta (THRβ) selective small molecule agonist. It is being evaluated in combination with semaglutide for the treatment of obesity.

                          Product Name : Undisclosed

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          December 18, 2024

                          Lead Product(s) : ASC47,Semaglutide

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          BIO CEO & Investor
                          Not Confirmed
                          BIO CEO & Investor
                          Not Confirmed

                          Details : ACCG-2671 is an oral small molecule amylin receptor agonist, which is currently being evaluated for the treatment of obesity.

                          Product Name : ACCG-2671

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          December 17, 2024

                          Lead Product(s) : ACCG-2671

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          BIO CEO & Investor
                          Not Confirmed
                          BIO CEO & Investor
                          Not Confirmed

                          Details : PeptiDream has discovered a series of potent macrocyclic and bridged-macrocyclic peptide inhibitors of myostatin, which are being evaluated for the treatment of obesity.

                          Product Name : Undisclosed

                          Product Type : Peptide

                          Upfront Cash : Not Applicable

                          December 12, 2024

                          Lead Product(s) : Undisclosed,Semaglutide

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          BIO CEO & Investor
                          Not Confirmed
                          BIO CEO & Investor
                          Not Confirmed

                          Details : BP1001-A works by binding directly to Grb2 mRNA, preventing its translation into the Grb2 protein. It is currently being evaluated for the treatment of obesity and related metabolic diseases.

                          Product Name : Undisclosed

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          December 11, 2024

                          Lead Product(s) : Prexigebersen

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          BIO CEO & Investor
                          Not Confirmed
                          BIO CEO & Investor
                          Not Confirmed

                          Details : BLX-7006 is an oral small molecule GLP-1 agonist, which is evaluated to provide potential breakthroughs in the global fight against obesity.

                          Product Name : Undisclosed

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          December 09, 2024

                          Lead Product(s) : BLX-7006

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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