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    [{"orgOrder":0,"company":"Nuvation Bio","sponsor":"Panacea Acquisition","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Merger","leadProduct":"NUV-422","moa":"CDK2\/4\/6","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Nuvation Bio","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Inhalation","sponsorNew":"Nuvation Bio \/ Panacea Acquisition","highestDevelopmentStatusID":"7","companyTruncated":"Nuvation Bio \/ Panacea Acquisition"},{"orgOrder":0,"company":"Nuvation Bio","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"NUV-422","moa":"CDK2\/4\/6","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Nuvation Bio","amount2":0,"highestDevelopmentShortName":"Ph 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Bio","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Nuvation Bio \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Nuvation Bio \/ Inapplicable"},{"orgOrder":0,"company":"Nuvation Bio","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Enzalutamide","moa":"||CDK2\/4\/6","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Nuvation Bio","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Nuvation Bio \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Nuvation Bio \/ Inapplicable"},{"orgOrder":0,"company":"Nuvation 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Sagard Healthcare Partners"}]

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                            01

                            Nuvation Bio

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                            Lead Product(s) : Taletrectinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Sagard Healthcare Partners

                            Deal Size : $250.0 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            Nuvation Bio Secures Up to $250M Non-Dilutive Financing from Sagard

                            Details : The financing is intended to support the clinical development and commercialization of AB-106 (taletrectinib), in the U.S. Currently, it is being evaluated for the treatment of ROS1-positive NSCLC.

                            Product Name : AB-106

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            March 03, 2025

                            Lead Product(s) : Taletrectinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Sagard Healthcare Partners

                            Deal Size : $250.0 million

                            Deal Type : Financing

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                            02

                            Nuvation Bio

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                            Lead Product(s) : Taletrectinib

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nuvation Launches Expanded Access for Taletrectinib in ROS1+ NSCLC in the U.S.

                            Details : AB-106 (taletrectinib adipate) is a next-generation ROS1 TKI, which is indicated for the treatment of adult patients with locally advanced or metastatic NSCLC.

                            Product Name : AB-106

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            February 03, 2025

                            Lead Product(s) : Taletrectinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

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                            Lead Product(s) : Taletrectinib

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nuvation Gets China NMPA Approval for Taletrectinib in NSCLC

                            Details : Dovbleron (taletrectinib) is a next-generation ROS1 TKI, which is indicated for the treatment of adult patients with locally advanced or metastatic NSCLC.

                            Product Name : Dovbleron

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            January 06, 2025

                            Lead Product(s) : Taletrectinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Nuvation Bio

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                            Lead Product(s) : Taletrectinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            U.S. FDA Accepts Priority Review for Taletrectinib in ROS1-positive NSCLC

                            Details : AB-106 (taletrectinib) is a next-generation ROS1 TKI, which is being evaluated for the treatment of adult patients with locally advanced or metastatic NSCLC.

                            Product Name : AB-106

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            December 23, 2024

                            Lead Product(s) : Taletrectinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Nuvation Bio

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                            Lead Product(s) : Taletrectinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nuvation Bio to Head to FDA with Pooled ROS1-Positive Lung Cancer Data

                            Details : AB-106 (taletrectinib) is a next-generation ROS1 TKI, which is being evaluated for the treatment of adult patients with locally advanced or metastatic NSCLC.

                            Product Name : AB-106

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            September 14, 2024

                            Lead Product(s) : Taletrectinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Nuvation Bio

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                            Lead Product(s) : NUV-1511

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nuvation Bio Gets FDA Clearance for IND Application for NUV-1511 in Advanced Solid Tumors

                            Details : NUV-1511 is the first clinical candidate from the company’s novel drug-drug conjugate (DDC) platform. It is being evaluated in preclinical studies for the treatment of advanced solid tumors.

                            Product Name : NUV-1511

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            August 01, 2024

                            Lead Product(s) : NUV-1511

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Nuvation Bio

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                            Lead Product(s) : NUV-1511

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nuvation Bio Doses First Patient in Phase 1/2 Study Of NUV-1511

                            Details : NUV-1511 is the first clinical DDC platform candidate for advanced solid tumors, including HER2-negative metastatic breast cancer and metastatic castration-resistant prostate cancer.

                            Product Name : NUV-1511

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            March 14, 2024

                            Lead Product(s) : NUV-1511

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Nuvation Bio

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                            Lead Product(s) : NUV-868,Olaparib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nuvation Bio Doses First Patient in Phase 1b Combination Study of NUV-868

                            Details : Patients in the first regimen will be dosed with NUV-868 in combination with olaparib for the treatment of ovarian cancer, pancreatic cancer, metastatic castration-resistant prostate cancer (mCRPC), triple negative breast cancer and other solid tumors.

                            Product Name : NUV-868

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            December 19, 2022

                            Lead Product(s) : NUV-868,Olaparib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Nuvation Bio

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                            Nuvation Bio

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                            Lead Product(s) : NUV-422

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nuvation Bio Provides Corporate Update and Highlights Key 2022 Milestones

                            Details : NUV-422, a selective small-molecule cyclin-dependent kinase (CDK) 2/4/6 inhibitor, has also received ODD for the treatment of patients with malignant gliomas and FTD for the treatment of high-grade gliomas from USFDA.

                            Product Name : NUV-422

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            October 01, 2022

                            Lead Product(s) : NUV-422

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Nuvation Bio

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                            Lead Product(s) : NUV-422

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nuvation Bio Announces FDA Partial Clinical Hold for Phase 1 Study of NUV-422 in Solid Tumors

                            Details : Preclinical studies have shown that NUV-422 has favorable blood-brain barrier penetration. NUV-422 is also designed to limit CDK1 inhibition, a potential cause of toxicity in other second-generation inhibitors.

                            Product Name : NUV-422

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            June 24, 2022

                            Lead Product(s) : NUV-422

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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