Lead Product(s) : NX-13
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : AbbVie Inc
Deal Size : $212.5 million
Deal Type : Acquisition
AbbVie To Acquire Landos Biopharma, Strengthening Portfolio in Inflammatory Diseases
Details : AbbVie will advance Landos’ lead investigational asset NX-13, a first-in-class, oral NLRX1 agonist with a bimodal mechanism of action, which is anti-inflammatory and facilitates epithelial repair.
Brand Name : NX-13
Molecule Type : Small molecule
Upfront Cash : $137.5 million
March 25, 2024
Lead Product(s) : NX-13
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : AbbVie Inc
Deal Size : $212.5 million
Deal Type : Acquisition
Lead Product(s) : NX-13
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : KU Leuven
Deal Size : Undisclosed
Deal Type : Collaboration
Details : The collaboration aims to investigate the effects of NX-13, first-in-class, oral, gut-selective, NLRX1 agonist, on epithelial cells with the Inflammatory Bowel Disease.
Brand Name : NX-13
Molecule Type : Small molecule
Upfront Cash : Undisclosed
September 14, 2023
Lead Product(s) : NX-13
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : KU Leuven
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : NX-13
Therapeutic Area : Gastroenterology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NX-13 is a first-in-class novel, gut-selective oral therapeutic candidate that targets NLRX1 that has been associated with the modulation of inflammatory cytokines for UC and CD.
Brand Name : NX-13
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 11, 2023
Lead Product(s) : NX-13
Therapeutic Area : Gastroenterology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NX-13
Therapeutic Area : Gastroenterology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : $16.7 million
Deal Type : Private Placement
Landos Biopharma Announces $16.7 Million Private Placement Financing
Details : Landos Biopharma anticipates using the net proceeds from the investment to advance the development of NX-13 for Ulcerative Colitis and Crohn’s Disease and for other general corporate purposes.
Brand Name : NX-13
Molecule Type : Small molecule
Upfront Cash : Undisclosed
January 05, 2023
Lead Product(s) : NX-13
Therapeutic Area : Gastroenterology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : $16.7 million
Deal Type : Private Placement
Lead Product(s) : NX-13
Therapeutic Area : Gastroenterology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Landos Biopharma Reports Positive Top-Line Results From NX-13 Phase 1b Trial
Details : NX-13 is a novel, gut-restricted, orally active, small molecule therapeutic candidate for the treatment of UC. NX-13 targets NLRX1, a mitochondria-associated receptor with the ability to modulate immune responses.
Brand Name : NX-13
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 03, 2022
Lead Product(s) : NX-13
Therapeutic Area : Gastroenterology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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