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Find Clinical Drug Pipeline Developments & Deals for NX-13

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                          Top Deals by Deal Size (USD bn)

                          01

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : AbbVie will advance Landos’ lead investigational asset NX-13, a first-in-class, oral NLRX1 agonist with a bimodal mechanism of action, which is anti-inflammatory and facilitates epithelial repair.

                          Brand Name : NX-13

                          Molecule Type : Small molecule

                          Upfront Cash : $137.5 million

                          March 25, 2024

                          Lead Product(s) : NX-13

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase II

                          Sponsor : AbbVie Inc

                          Deal Size : $212.5 million

                          Deal Type : Acquisition

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                          02

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : The collaboration aims to investigate the effects of NX-13, first-in-class, oral, gut-selective, NLRX1 agonist, on epithelial cells with the Inflammatory Bowel Disease.

                          Brand Name : NX-13

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          September 14, 2023

                          Lead Product(s) : NX-13

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase II

                          Sponsor : KU Leuven

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          03

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : NX-13 is a first-in-class novel, gut-selective oral therapeutic candidate that targets NLRX1 that has been associated with the modulation of inflammatory cytokines for UC and CD.

                          Brand Name : NX-13

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          January 11, 2023

                          Lead Product(s) : NX-13

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Landos Biopharma anticipates using the net proceeds from the investment to advance the development of NX-13 for Ulcerative Colitis and Crohn’s Disease and for other general corporate purposes.

                          Brand Name : NX-13

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          January 05, 2023

                          Lead Product(s) : NX-13

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase I

                          Sponsor : Undisclosed

                          Deal Size : $16.7 million

                          Deal Type : Private Placement

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                          05

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : NX-13 is a novel, gut-restricted, orally active, small molecule therapeutic candidate for the treatment of UC. NX-13 targets NLRX1, a mitochondria-associated receptor with the ability to modulate immune responses.

                          Brand Name : NX-13

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          August 03, 2022

                          Lead Product(s) : NX-13

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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