Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : NXP900,Osimertinib Mesylate
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Nuvectis’ NXP900 Plus Tagrisso Shows NSCLC Efficacy, New Buy Rating
Details : NXP900 is an oral SRC/YES1 kinase inhibitor is being investigated in combination with osimertinib (Tagrisso®) in EGFR-mutated non-small cell lung cancer (NSCLC) models.
Product Name : NXP900
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 05, 2025
Lead Product(s) : NXP900,Osimertinib Mesylate
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : NXP900,Alectinib Hydrochloride
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Nuvectis' NXP900 Shows Strong Activity in Non-Small Lung Cancer Cells
Details : NXP900 is an oral small molecule inhibitor of the SRC Family of Kinases is being evaluated in early-stage clinical trial in combination with Alectinib for the treatment of non-small cell lung cancer.
Product Name : NXP900
Product Type : Small molecule
Upfront Cash : Not Applicable
April 08, 2024
Lead Product(s) : NXP900,Alectinib Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Nuvectis Pharma Announces Initiation of the NXP900 Phase 1a Clinical Trial
Details : NXP900 is a novel inhibitor of the SRC family of kinases with low nanomolar potency against YES1 and SRC. It has demonstrated robust single agent antitumor activity in several in vivo oncological xenograft models.
Product Name : NXP900
Product Type : Small molecule
Upfront Cash : Not Applicable
September 12, 2023
Lead Product(s) : NXP900
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Nuvectis Pharma Announces FDA Clearance of NXP900 IND
Details : NXP900 is a novel inhibitor of the SRC family of kinases with low nanomolar potency against YES1 and SRC. It has demonstrated robust single agent antitumor activity in several in vivo oncological xenograft models.
Product Name : NXP900
Product Type : Small molecule
Upfront Cash : Not Applicable
May 15, 2023
Lead Product(s) : NXP900
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NXP900
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NXP900's abilities to inhibit the SRC kinase and to cross the blood-brain barrier have been previously demonstrated, translating into potent and durable tumor growth inhibition in this preclinical model.
Product Name : NXP900
Product Type : Small molecule
Upfront Cash : Not Applicable
June 13, 2022
Lead Product(s) : NXP900
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NXP900
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Institute of Genetics and Cancer
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NXP900, highly-selective SRC/YES1 inhibitor robust activity in preclinical models of TNBC with ILK loss effectively shuts down SRC-mediated signaling by inhibiting both the catalytic and scaffolding functions of SRC/YES1 kinases, without triggering immu...
Product Name : NXP900
Product Type : Small molecule
Upfront Cash : Not Applicable
February 22, 2022
Lead Product(s) : NXP900
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Institute of Genetics and Cancer
Deal Size : Not Applicable
Deal Type : Not Applicable