2
ALL2
Daiichi SankyoYear
2
ALL1
20221
2021DEALS // DEV.
2
ALL2
DevelopmentsCountry
2
ALL2
JAPAN2
ALL1
Inapplicable1
Sarah Cannon Research InstituteTherapeutic Area
2
ALL2
OncologyStudy Phase
2
ALL2
Phase IIDeal Type
2
ALL2
InapplicableProduct Type
2
ALL2
Antibody-drug ConjugateDosage Form
2
ALL2
Intravenous InfusionLead Product
2
ALL2
O-(3,5-Dichlorophenyl)hydroxylamineTarget
2
ALL2
UndisclosedLead Product(s) : O-(3,5-Dichlorophenyl)hydroxylamine
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
DS-7300 Phase 2 Trial Initiated in Patients with Pretreated Extensive-Stage Small Cell Lung Cancer
Details : DS-7300,s an investigational B7-H3 directed ADC is comprised of a humanized anti-B7-H3 IgG1 monoclonal antibody attached to a number of topoisomerase I inhibitor payloads (an exatecan derivative, DXd) via tetrapeptidebased cleavable linkers.
Product Name : DS-7300
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
July 20, 2022
Lead Product(s) : O-(3,5-Dichlorophenyl)hydroxylamine
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : O-(3,5-Dichlorophenyl)hydroxylamine
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Sarah Cannon Research Institute
Deal Size : Inapplicable
Deal Type : Inapplicable
DS-7300 Data at ESMO Shows Promising Early Clinical Activity in Patients with Advanced Solid Cancers
Details : DS-7300, a B7-H3 directed DXd antibody drug conjugate (ADC) showed promising early clinical activity in patients with several types of advanced solid tumors that are refractory or intolerable to standard treatment or for whom no standard treatment exists...
Product Name : DS-7300
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
September 17, 2021
Lead Product(s) : O-(3,5-Dichlorophenyl)hydroxylamine
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Sarah Cannon Research Institute
Deal Size : Inapplicable
Deal Type : Inapplicable