Lead Product(s) : O-(3,5-Dichlorophenyl)hydroxylamine
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
DS-7300 Phase 2 Trial Initiated in Patients with Pretreated Extensive-Stage Small Cell Lung Cancer
Details : DS-7300,s an investigational B7-H3 directed ADC is comprised of a humanized anti-B7-H3 IgG1 monoclonal antibody attached to a number of topoisomerase I inhibitor payloads (an exatecan derivative, DXd) via tetrapeptidebased cleavable linkers.
Brand Name : DS-7300
Molecule Type : Large molecule
Upfront Cash : Not Applicable
July 20, 2022
Lead Product(s) : O-(3,5-Dichlorophenyl)hydroxylamine
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : O-(3,5-Dichlorophenyl)hydroxylamine
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Sarah Cannon Research Institute
Deal Size : Not Applicable
Deal Type : Not Applicable
DS-7300 Data at ESMO Shows Promising Early Clinical Activity in Patients with Advanced Solid Cancers
Details : DS-7300, a B7-H3 directed DXd antibody drug conjugate (ADC) showed promising early clinical activity in patients with several types of advanced solid tumors that are refractory or intolerable to standard treatment or for whom no standard treatment exists...
Brand Name : DS-7300
Molecule Type : Large molecule
Upfront Cash : Not Applicable
September 17, 2021
Lead Product(s) : O-(3,5-Dichlorophenyl)hydroxylamine
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Sarah Cannon Research Institute
Deal Size : Not Applicable
Deal Type : Not Applicable
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