Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : OBI-992
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
OBI Pharma Initiates Phase 1/2 Study for OBI-992, a TROP2-Targeted ADC
Details : OBI-992 is a novel antibody drug conjugate (ADC) cancer therapy targeting TROP2. It is being evaluated for the treatment of non-small cell lung cancer, small cell lung cancer & gastric cancer.
Brand Name : OBI-992
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 12, 2024
Lead Product(s) : OBI-992
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : OBI-992
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Biosion
Deal Size : Not Applicable
Deal Type : Not Applicable
Biosion's Partner OBI Pharma Announces FDA Clearance for OBI-992 Phase 1/2 Study
Details : OBI-992 is a novel antibody drug conjugate (ADC) cancer therapy targeting TROP2. It is being evaluated for the treatment of non-small cell lung cancer, small cell lung cancer & gastric cancer.
Brand Name : OBI-992
Molecule Type : Large molecule
Upfront Cash : Not Applicable
January 08, 2024
Lead Product(s) : OBI-992
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Biosion
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : OBI-992
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
OBI Pharma Announces FDA Clearance for Phase 1/2 Study of OBI-992
Details : OBI-992 is a TROP2-targeted antibody-drug conjugate delivering a topoisomerase I inhibitor, evaluated for advanced solid tumors including lung and gastric cancers.
Brand Name : OBI-992
Molecule Type : Large molecule
Upfront Cash : Not Applicable
January 03, 2024
Lead Product(s) : OBI-992
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : OBI-888
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : A first in class monoclonal antibody cancer immunotherapy, OBI-888 targets Globo H, antibody, a glycolipid antigen expressed in up to 15 epithelial cancers.
Brand Name : OBI-888
Molecule Type : Large molecule
Upfront Cash : Not Applicable
July 05, 2022
Lead Product(s) : OBI-888
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : OBI-999
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : OBI-999, uses Globo H antibody to recognize the cancer cells with high Globo H expression and releases the active drug to prevent tumor growth and kill tumor cells.
Brand Name : OBI-999
Molecule Type : Large molecule
Upfront Cash : Not Applicable
May 17, 2022
Lead Product(s) : OBI-999
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : OBI-3424,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : OBI-3424 can induce immunogenic cell death and demonstrated impressive synergistic efficacy in combination with Pembrolizumab in various cancer models, Emerging science also demonstrated poor survival in gastric cancer patients who have high Globo H and ...
Brand Name : OBI-3424
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 07, 2022
Lead Product(s) : OBI-3424,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BSI04702
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : Biosion
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : The license agreement enables OBI Pharma to conduct further preclinical and clinical development, registration, and commercialization of BSI04702 as an Antibody Drug Conjugate and other derivative products.
Brand Name : BSI04702
Molecule Type : Large molecule
Upfront Cash : Undisclosed
December 13, 2021
Lead Product(s) : BSI04702
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : Biosion
Deal Size : Undisclosed
Deal Type : Licensing Agreement
OBI Pharma Announces Presentations at ESMO Asia 2020 Virtual Annual Meeting for OBI-833
Details : In the trial, OBI-833 showed a favorable safety profile and generated detectable anti-Globo H IgM/IgG responses. The company’s novel first-in-class immuno-oncology portfolio against Globo H includes: Adagloxad Simolenin and OBI-833, a Globo H active im...
Brand Name : OBI-833
Molecule Type : Vaccine
Upfront Cash : Not Applicable
November 19, 2020
Details : Poster Presentations to highlight the ongoing clinical studies targeting Globo H and AKR1C3 antigens in different tumor types.
Brand Name : Undisclosed
Molecule Type : Vaccine
Upfront Cash : Not Applicable
May 20, 2020
Lead Product(s) : OBI-999
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Second Orphan Drug Designation for OBI-999, Antibody-Drug Conjugate in combination with a validated payload (MMAE) & the antibody targeting Globo H, a glycolipid antigen found on multiple tumor types.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Not Applicable
January 21, 2020
Lead Product(s) : OBI-999
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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