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    [{"orgOrder":0,"company":"Obsidian Therapeutics","sponsor":"Vertex Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Undisclosed","year":"2021","type":"Collaboration","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Genetic Disease","graph2":"Discovery Platform","graph3":"Obsidian Therapeutics","amount2":0,"highestDevelopmentShortName":"Discovery Platform","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Obsidian Therapeutics \/ Vertex Pharmaceuticals","highestDevelopmentStatusID":"3","companyTruncated":"Obsidian Therapeutics \/ Vertex Pharmaceuticals"},{"orgOrder":0,"company":"Obsidian Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2023","type":"Inapplicable","leadProduct":"Cyclophosphamide","moa":"||IL-15 receptor","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Obsidian Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Obsidian Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Obsidian Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Obsidian Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"CytoTIL15","moa":"Undisclosed","graph1":"Oncology","graph2":"Preclinical","graph3":"Obsidian Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Inhalation","sponsorNew":"Obsidian Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Obsidian Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Obsidian Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"CytoTIL15","moa":"Undisclosed","graph1":"Oncology","graph2":"Preclinical","graph3":"Obsidian Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Inhalation","sponsorNew":"Obsidian Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Obsidian Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Obsidian Therapeutics","sponsor":"Wellington Management","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2024","type":"Series C Financing","leadProduct":"OBX-115","moa":"IL-15 receptor","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Obsidian Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Obsidian Therapeutics \/ Wellington Management","highestDevelopmentStatusID":"7","companyTruncated":"Obsidian Therapeutics \/ Wellington Management"}]

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                            01

                            Obsidian Therapeutics

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                            AACR Annual meeting
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                            Obsidian Therapeutics

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                            Lead Product(s) : OBX-115

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Wellington Management

                            Deal Size : $160.5 million

                            Deal Type : Series C Financing

                            DEALS_DEV arrow-down

                            Obsidian Therapeutics Rakes in $160M for Solid Tumor Cell Therapy Program

                            Details : The Proceeds from the financing will advance Obsidian’s lead-engineered tumor-infiltrating lymphocyte program, OBX-115, for patients with melanoma and non-small cell lung cancer.

                            Product Name : OBX-115

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            March 04, 2024

                            Lead Product(s) : OBX-115

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Wellington Management

                            Deal Size : $160.5 million

                            Deal Type : Series C Financing

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                            02

                            Obsidian Therapeutics

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                            AACR Annual meeting
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                            Lead Product(s) : OBX-115,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Obsidian Therapeutics Announces Positive Interim Top-Line Clinical Data for OBX-115 Engineered TIL Cell Therap...

                            Details : OBX-115 is a cell and gene therapy drug candidate, which is being evaluated in combination with for the treatment of patients with advanced or metastatic melanoma.

                            Product Name : OBX-115

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            December 12, 2023

                            Lead Product(s) : OBX-115,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Obsidian Therapeutics

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                            AACR Annual meeting
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                            Lead Product(s) : CytoTIL15

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Obsidian Therapeutics To Present Preclinical Data From cytoTIL15 Program at the European Society for Medical O...

                            Details : The abstract for the poster describes how Obsidian’s cytoTIL15 product demonstrates enhanced in vitro potency and phenotype and in vivo persistence in the absence of IL-2, paving the way for more durable efficacy and improved safety in patients with so...

                            Product Name : CytoTIL15

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            September 15, 2021

                            Lead Product(s) : CytoTIL15

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Obsidian Therapeutics

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                            Lead Product(s) : CytoTIL15

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Obsidian Therapeutics to Present In Vivo Anti-Tumor Efficacy Data from Novel Engineered cytoTIL15 Program at S...

                            Details : The observed in vitro and in vivo persistence of cytoTIL15 TILs, in the absence of IL2, to superior in vivo anti-tumor efficacy in PDX models supports the potential for increased efficacy of cytoTIL15 therapy over conventional TIL therapy in solid tumor ...

                            Product Name : CytoTIL15

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            September 11, 2021

                            Lead Product(s) : CytoTIL15

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Obsidian Therapeutics

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Genetic Disease

                            Study Phase : Discovery Platform

                            Sponsor : Vertex Pharmaceuticals

                            Deal Size : $1,300.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Vertex and Obsidian Therapeutics Establish Collaboration to Discover Novel Therapies That Regulate Gene Editin...

                            Details : This multi-year strategic research collaboration leverages Obsidian’s proprietary cytoDRiVE® platform to discover controllable genetic therapies to treat serious diseases.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : $75.0 million

                            April 22, 2021

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Discovery Platform

                            Sponsor : Vertex Pharmaceuticals

                            Deal Size : $1,300.0 million

                            Deal Type : Collaboration

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