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                          01

                          Pharma Live Expo
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                          Pharma Live Expo
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                          Details : Kayfanda (odevixibat) is a once-daily non-systemic IBAT inhibitor, being evaluated for the treatment of cholestatic pruritus in Alagille Syndrome in patients aged 6 months or older.

                          Product Name : Bylvay

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          September 23, 2024

                          Lead Product(s) : Odevixibat

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : Bylvay (odevixibat) is a potent, once-daily, non-systemic IBATi that acts locally in the small intestine and has minimal systemic exposure. It is approved in the U.S. for the treatment of pruritus due to Progressive Familial Intrahepatic Cholestasis.

                          Product Name : Bylvay

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          November 13, 2023

                          Lead Product(s) : Odevixibat

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : Bylvay (odevixibat) is a potent, once-daily, non-systemic IBATi that acts locally in the small intestine and has minimal systemic exposure. It is approved in the U.S. for the treatment of Alagille syndrome.

                          Product Name : Bylvay

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          October 23, 2023

                          Lead Product(s) : Odevixibat

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : Albireo’s pipeline includes Bylvay® (odevixibat), a potent, once-daily, oral, non-systemic ileal bile acid transport inhibitor. Bylvay is being investigated in biliary atresia, a severe and potentially fatal pediatric liver disease, in a pivotal Phase...

                          Product Name : Bylvay

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          September 01, 2023

                          Lead Product(s) : Odevixibat

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Approved FDF

                          Sponsor : Ipsen

                          Deal Size : $952.0 million

                          Deal Type : Acquisition

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                          05

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : Bylvay (odevixibat) is a potent, once-daily, non-systemic IBATi that acts locally in the small intestine and has minimal systemic exposure. It is approved in the U.S. for the treatment of Alagille syndrome.

                          Product Name : Bylvay

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          July 21, 2023

                          Lead Product(s) : Odevixibat

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : Bylvay (Odevixibat) is theI BAT inhibitor and first drug approved in the U.S. for the treatment of pruritus in patients 3 months of age and older in all types of progressive familial intrahepatic cholestasis (PFIC).

                          Product Name : Bylvay

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          June 20, 2023

                          Lead Product(s) : Odevixibat

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Approved FDF

                          Sponsor : Albireo Pharma

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : Bylvay (odevixibat) is a potent, once-daily, non-systemic IBATi that acts locally in the small intestine and has minimal systemic exposure. It is approved in the U.S. for the treatment of Alagille syndrome.

                          Product Name : Bylvay

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          June 13, 2023

                          Lead Product(s) : Odevixibat

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : The acquisition enriches Ipsen’s Rare Disease portfolio including Bylvay (odevixibat), a potent, non-systemic ileal bile-acid transport inhibitor (IBATi), for the treatment of pruritus in patients three months of age and older with PFIC.

                          Product Name : Bylvay

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          March 03, 2023

                          Lead Product(s) : Odevixibat

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Approved FDF

                          Sponsor : Ipsen

                          Deal Size : $952.0 million

                          Deal Type : Acquisition

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                          09

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : Bylvay (odevixibat) is used for the treatment of pruritus in patients 3 months of age and older in all types of PFIC. A potent, once-daily, non-systemic ileal bile acid transport inhibitor, Bylvay has minimal systemic exposure and acts locally in the sma...

                          Product Name : Bylvay

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          November 30, 2022

                          Lead Product(s) : Odevixibat

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : In primary analysis of Bylvay (odevixibat) study met primary endpoint showing statistically significant reduction in pruritus as measured by PRUCISION Observer-Reported Outcome scratching score, from baseline at month 6 (weeks 21 to 24), compared to plac...

                          Product Name : Bylvay

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          November 10, 2022

                          Lead Product(s) : Odevixibat

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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