Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : OLX-07010
Therapeutic Area : Neurology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : OLX-07010 is an oral, small molecule inhibitor of tau self-association that targets the beginning of the tau aggregation cascade, a process believed to be implicated in the development of Alzheimer’s disease and other neurodegenerative disorders.
Brand Name : OLX-07010
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 30, 2022
Lead Product(s) : OLX-07010
Therapeutic Area : Neurology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : OLX-07010
Therapeutic Area : Neurology
Study Phase : IND Enabling
Sponsor : National Institute on Aging
Deal Size : $3.4 million
Deal Type : Funding
Details : OLX-07010 would potentially fill a significant unmet need with a disease-modifying drug that, if successful, will have a tremendous impact on patient outcomes and reduce the burden on caregivers and society.
Brand Name : OLX-07010
Molecule Type : Small molecule
Upfront Cash : Undisclosed
August 09, 2022
Lead Product(s) : OLX-07010
Therapeutic Area : Neurology
Highest Development Status : IND Enabling
Sponsor : National Institute on Aging
Deal Size : $3.4 million
Deal Type : Funding
Lead Product(s) : OLX07010
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : $2.7 million
Deal Type : Series B Financing
Details : The lead candidate OLX07010, has demonstrated efficacy in animal models of tau-mediated neurodegeneration. Preclinical safety studies are completed and Phase 1a clinical studies are planned to initiate in the third quarter of 2022.
Brand Name : OLX-07010
Molecule Type : Small molecule
Upfront Cash : Undisclosed
June 03, 2022
Lead Product(s) : OLX07010
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : $2.7 million
Deal Type : Series B Financing
Lead Product(s) : OLX-07010
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : A study was conducted in the tau P301L JNPL3 mouse model for tau aggregation and motor impairment that was aged prior to treatment in order to study the therapeutic effect of OLX-07010.
Brand Name : OLX-07010
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 09, 2021
Lead Product(s) : OLX-07010
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : OLX07010
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : OLX07010, has demonstrated efficacy in several animal models of neurodegeneration and, upon completion of its preclinical program in the next couple of months, will start Phase 1 clinical studies in early 2022.
Brand Name : OLX07010
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 30, 2021
Lead Product(s) : OLX07010
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : OLX-07010
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Oligomerix to Present at Alzheimer's Association International Conference
Details : Company will be presenting preclinical data on its oral, tau self-association small molecule inhibitor lead program, OLX-07010, at the 2021 Alzheimer's Association International Conference.
Brand Name : OLX-07010
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 26, 2021
Lead Product(s) : OLX-07010
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Oligomerix to Present at Clinical Trials on Alzheimer’s Disease Conference & Life Sciences Summit
Details : Poster titled "Therapeutic efficacy of a small molecule inhibitor targeting tau self-association in mouse models of tauopathy" will be presented at the 13th Clinical Trials on Alzheimer’s Disease Conference 2020 Digital Event.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 29, 2020
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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