Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : OLP-1002
Therapeutic Area : Musculoskeletal
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : OLP-1002 is an SCN9A antisense PNA and selectively inhibits the expression of Nav1.7 sodium channel in neuronal cells. It replicates much of the phenotype of people with a null mutation in the SCN9A gene. It is being investigated for chronic osteoarthrit...
Brand Name : OLP-1002
Molecule Type : Large molecule
Upfront Cash : Not Applicable
November 13, 2023
Lead Product(s) : OLP-1002
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : OLP-1002
Therapeutic Area : Musculoskeletal
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : OLP-1002 is an SCN9A antisense PNA and selectively inhibits the expression of Nav1.7 sodium channel in neuronal cells. It replicates much of the phenotype of people with a null mutation in the SCN9A gene. It is being investigated for chronic osteoarthrit...
Brand Name : OLP-1002
Molecule Type : Large molecule
Upfront Cash : Not Applicable
March 16, 2023
Lead Product(s) : OLP-1002
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Antisense Oligonucleotide
Therapeutic Area : Technology
Study Phase : Preclinical
Recipient : Vanda Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Partnership
Details : The collaboration will focus on editing and modifying gene expression using ASOs in disease states where the expression of genes is either altered or the sequence of the expressed genes can be altered for therapeutic benefit.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
September 29, 2022
Lead Product(s) : Antisense Oligonucleotide
Therapeutic Area : Technology
Highest Development Status : Preclinical
Recipient : Vanda Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : OLP-1002
Therapeutic Area : Musculoskeletal
Study Phase : Phase II
Sponsor : Novotech
Deal Size : Not Applicable
Deal Type : Not Applicable
OliPass Moves Forward to Second Stage of Phase 2a Trial for Pain Killer OLP-1002
Details : OLP-1002 is an SCN9A antisense peptide nucleic acid (PNA) and selectively inhibits the expression of Nav1.7 sodium channel, and therefore expected to replicate much of the phenotype of people with SCN9A channelopathy.
Brand Name : OLP-1002
Molecule Type : Large molecule
Upfront Cash : Not Applicable
July 18, 2022
Lead Product(s) : OLP-1002
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase II
Sponsor : Novotech
Deal Size : Not Applicable
Deal Type : Not Applicable
SCN9A Antisense Pain Killer OLP-1002 Moves into Phase 2a Stage
Details : OLP-1002 manifested excellent safety in a UK Phase 1 study evaluated in a total of 116 healthy volunteers. In the meantime, an exploratory Phase 1b study in Australia suggested clues to strong efficacy and long therapeutic duration in OA patients.
Brand Name : OLP-1002
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 25, 2021
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