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    [{"orgOrder":0,"company":"Forma Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Olutasidenib","moa":"IDH-1","graph1":"Oncology","graph2":"Phase II","graph3":"Forma Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Forma Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Forma Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Forma Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Olutasidenib","moa":"IDH-1","graph1":"Oncology","graph2":"Phase II","graph3":"Forma Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph 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    Olutasidenib

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                            01

                            Rigel Pharmaceuticals

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                            euroPLX 86 Munich
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                            Rigel Pharmaceuticals

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                            Lead Product(s) : Olutasidenib,Decitabine,Venetoclax

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Rigel Enrolls First Patient in Phase 1b/2 Trial of REZLIDHIA® for mIDH1 AML

                            Details : Decitabine and venetoclax in combination with Rezlidhia (olutasidenib) in patients with mutated isocitrate dehydrogenase-1 (mIDH1) acute myeloid leukemia (AML).

                            Brand Name : Rezlidhia

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 05, 2024

                            Lead Product(s) : Olutasidenib,Decitabine,Venetoclax

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Rigel Pharmaceuticals

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                            euroPLX 86 Munich
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                            Rigel Pharmaceuticals

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                            euroPLX 86 Munich
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                            Lead Product(s) : Olutasidenib

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Kissei Pharmaceutical

                            Deal Size : $162.5 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Rigel Expands REZLIDHIA® Partnership with Kissei for Japan, Korea, Taiwan

                            Details : The agreement aims to develop and commercialize Rezlidhia (olutasidenib) in all current and potential indications in Japan, the Republic of Korea and Taiwan.

                            Brand Name : Rezlidhia

                            Molecule Type : Small molecule

                            Upfront Cash : $10.0 million

                            September 03, 2024

                            Lead Product(s) : Olutasidenib

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Kissei Pharmaceutical

                            Deal Size : $162.5 million

                            Deal Type : Licensing Agreement

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                            03

                            Rigel Pharmaceuticals

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                            euroPLX 86 Munich
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                            Rigel Pharmaceuticals

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                            Lead Product(s) : Olutasidenib,Temozolomide

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : CONNECT

                            Deal Size : $3.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Rigel Collaborates with CONNECT for Olutasidenib Phase 2 Trial in Glioma

                            Details : The collaboration aims to conduct a Phase 2 clinical trial to evaluate Rezlidhia (olutasidenib) in combination with temozolomide for treating high-grade glioma harboring an IDH1 mutation.

                            Brand Name : Rezlidhia

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            January 04, 2024

                            Lead Product(s) : Olutasidenib,Temozolomide

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : CONNECT

                            Deal Size : $3.0 million

                            Deal Type : Collaboration

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                            04

                            Rigel Pharmaceuticals

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                            euroPLX 86 Munich
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                            Rigel Pharmaceuticals

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                            euroPLX 86 Munich
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                            Lead Product(s) : Olutasidenib,Azacitidine

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Rigel Announces Publication of REZLIDHIA™ (olutasidenib) Phase 2 Clinical Results in Blood Advances

                            Details : Rezlidhia (olutasidenib) is a small-molecule inhibitor of mutated isocitrate dehydrogenase-1 (IDH1). It is indicated for the treatment of adult patients with relapsed or refractory acute myeloid leukemia (AML) with a susceptibleisocitrate dehydrogenase-1...

                            Brand Name : Rezlidhia

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            February 02, 2023

                            Lead Product(s) : Olutasidenib,Azacitidine

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Rigel Pharmaceuticals

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                            euroPLX 86 Munich
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                            Rigel Pharmaceuticals

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                            euroPLX 86 Munich
                            Not Confirmed
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                            Lead Product(s) : Olutasidenib,Azacitidine

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            National Comprehensive Cancer Network® Adds Newly Approved Rezlidhia™ (Olutasidenib) to Clinical Practice G...

                            Details : Rezlidhia (olutasidenib) is a small-molecule inhibitor of mutated isocitrate dehydrogenase-1 (IDH1). It is indicated for the treatment of adult patients with relapsed or refractory acute myeloid leukemia (AML) with a susceptibleisocitrate dehydrogenase-1...

                            Brand Name : Rezlidhia

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            January 18, 2023

                            Lead Product(s) : Olutasidenib,Azacitidine

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Rigel Pharmaceuticals

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                            euroPLX 86 Munich
                            Not Confirmed

                            Rigel Pharmaceuticals

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                            euroPLX 86 Munich
                            Not Confirmed
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                            Lead Product(s) : Olutasidenib

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Rigel Announces Availability of REZLIDHIA™ (olutasidenib) in the U.S. for the Treatment of Adult Patients wi...

                            Details : REZLIDHIA is an oral, small molecule, inhibitor of mutated IDH1 designed to bind to and inhibit mIDH1 to reduce 2-hydroxyglutarate levels and restore normal cellular differentiation of myeloid cells.

                            Brand Name : Rezlidhia

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            December 22, 2022

                            Lead Product(s) : Olutasidenib

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Rigel Pharmaceuticals

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                            euroPLX 86 Munich
                            Not Confirmed

                            Rigel Pharmaceuticals

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                            euroPLX 86 Munich
                            Not Confirmed
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                            Lead Product(s) : Olutasidenib

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Optime Care

                            Deal Size : Undisclosed

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            Optime Care, Specialty Pharmacy Patient Management Organization Announces Enhanced Partnership with Rigel Phar...

                            Details : Rezlidhia (olutasidenib) is indicated for the treatment of adult patients with relapsed or refractory acute myeloid leukemia (AML) with a susceptible isocitrate dehydrogenase-1 (IDH1) mutation as detected by an FDA-approved test.

                            Brand Name : Rezlidhia

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            December 13, 2022

                            Lead Product(s) : Olutasidenib

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Optime Care

                            Deal Size : Undisclosed

                            Deal Type : Partnership

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                            08

                            Rigel Pharmaceuticals

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                            euroPLX 86 Munich
                            Not Confirmed

                            Rigel Pharmaceuticals

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                            euroPLX 86 Munich
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                            Lead Product(s) : Olutasidenib,Azacitidine

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Rigel Announces U.S. FDA Approval of REZLIDHIA™ (olutasidenib) for the Treatment of Adult Patients with Rela...

                            Details : REZLIDHIA (olutasidenib) is an oral, small molecule, inhibitor of mutated IDH1 designed to bind to and inhibit mIDH1 to reduce 2-hydroxyglutarate levels and restore normal cellular differentiation of myeloid cells.

                            Brand Name : Rezlidhia

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            December 02, 2022

                            Lead Product(s) : Olutasidenib,Azacitidine

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Rigel Pharmaceuticals

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                            euroPLX 86 Munich
                            Not Confirmed

                            Rigel Pharmaceuticals

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                            euroPLX 86 Munich
                            Not Confirmed
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                            Lead Product(s) : Olutasidenib,Azacitidine

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Rigel Announces U.S. FDA Approval of REZLIDHIA™ (olutasidenib) for the Treatment of Adult Patients with Rela...

                            Details : REZLIDHIA (olutasidenib) is an oral, small molecule, inhibitor of mutated IDH1 designed to bind to and inhibit mIDH1 to reduce 2-hydroxyglutarate levels and restore normal cellular differentiation of myeloid cells.

                            Brand Name : Rezlidhia

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            December 01, 2022

                            Lead Product(s) : Olutasidenib,Azacitidine

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            Rigel Pharmaceuticals

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                            euroPLX 86 Munich
                            Not Confirmed

                            Rigel Pharmaceuticals

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                            euroPLX 86 Munich
                            Not Confirmed
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                            Lead Product(s) : Olutasidenib,Azacitidine

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Rigel Announces Five Poster Presentations at the Upcoming 64th American Society of Hematology Annual Meeting a...

                            Details : FT-2102 (olutasidenib), is an oral, small molecule investigational agent designed to selectively bind to and inhibit mutated IDH1 enzymes,in patients with relapsed/refractory acute myeloid leukemia.

                            Brand Name : FT-2102

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            November 03, 2022

                            Lead Product(s) : Olutasidenib,Azacitidine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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