[{"orgOrder":0,"company":"Paratek Pharmaceuticals","sponsor":"BARDA","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Funding","leadProduct":"Omadacycline","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Approved","graph3":"Paratek Pharmaceuticals","amount2":0.28999999999999998,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Infectious Diseases","amount2New":0.28999999999999998,"dosageForm":"Oral","sponsorNew":"Paratek Pharmaceuticals \/ BARDA","highestDevelopmentStatusID":"12","companyTruncated":"Paratek Pharmaceuticals \/ BARDA"},{"orgOrder":0,"company":"Flexion Therapeutics","sponsor":"HK Tainuo","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Licensing Agreement","leadProduct":"Omadacycline","moa":"Glucocorticoid 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Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Paratek Pharmaceuticals \/ Not Applicable"},{"orgOrder":0,"company":"Paratek Pharmaceuticals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Small molecule","year":"2021","type":"Not Applicable","leadProduct":"Omadacycline","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"Paratek Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Paratek Pharmaceuticals \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Paratek Pharmaceuticals \/ Not Applicable"},{"orgOrder":0,"company":"Paratek Pharmaceuticals","sponsor":"BARDA","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Small 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Find Clinical Drug Pipeline Developments & Deals for Omadacycline

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : Omadacycline

                          Therapeutic Area : Infections and Infectious Diseases

                          Study Phase : Approved

                          Sponsor : Paratek Pharmaceuticals

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

                          Details : Under the terms of the collaboration, Novasep and Paratek will manufacture NUZYRA® (omadacycline), an FDA-approved tetracycline-class, once-daily oral and intravenous antibiotic for the treatment of adults with CABP and acute bacterial skin and skin str...

                          Brand Name : Nuzyra

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          February 15, 2022

                          Lead Product(s) : Omadacycline

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Paratek Pharmaceuticals

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

                          Axplora CB

                          02

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Nuzyra (omadacycline) is a USFDA approved novel antibiotic, being investigated in adults with Nontuberculous Mycobacterial pulmonary disease caused by Mycobacterium abscessus complex.

                          Brand Name : Nuzyra

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          November 08, 2024

                          Lead Product(s) : Omadacycline

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Nuzyra (omadacycline) is a USFDA approved novel antibiotic for the treatment of community-acquired bacterial pneumonia.

                          Brand Name : Nuzyra

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          July 31, 2024

                          Lead Product(s) : Omadacycline

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Nuzyra (omadacycline tosylate) is a USFDA approved novel antibiotic for the treatment of community-acquired bacterial pneumonia.

                          Brand Name : Nuzyra

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          July 18, 2024

                          Lead Product(s) : Omadacycline

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase IV

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Nuzyra (omadacycline) is a USFDA approved novel antibiotic for community-acquired bacterial pneumonia. Now it is being evaluated for post-exposure prophylaxis of inhalational anthrax.

                          Brand Name : Nuzyra

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          March 05, 2024

                          Lead Product(s) : Omadacycline

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : The proceeds from the acquisition will advance the commercialization of Nuzyra (omadacycline), a tetracycline antibiotic, indicated for the treatment of adult patients with community-acquired bacterial pneumonia, and support the development of additional...

                          Brand Name : Nuzyra

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          September 21, 2023

                          Lead Product(s) : Omadacycline

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Sponsor : Gurnet Point Capital

                          Deal Size : $462.0 million

                          Deal Type : Acquisition

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                          07

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : The agreement aims to support the development of omadacycline for post-exposure prophylaxis and pulmonary anthrax and the US-based commercial manufacturing of Nuzyra, a novel once-daily antibiotic approved for the treatment of community-acquired bacteria...

                          Brand Name : Nuzyra

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          July 10, 2023

                          Lead Product(s) : Omadacycline

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : BARDA

                          Deal Size : $304.0 million

                          Deal Type : Agreement

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                          08

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Nuzyra (omadacycline tosylate) is a novel antibiotic which binds to the 30S ribosomal subunit and blocks protein synthesis and is available for the treatment of of community-acquired bacterial pneumonia and acute bacterial skin and skin structure infecti...

                          Brand Name : Nuzyra

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          June 27, 2023

                          Lead Product(s) : Omadacycline

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : The proceeds from the acquisition will advance the commercialization of Nuzyra (omadacycline), a tetracycline antibiotic, indicated for the treatment of adult patients with community-acquired bacterial pneumonia, and support the development of additional...

                          Brand Name : Nuzyra

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          June 06, 2023

                          Lead Product(s) : Omadacycline

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Gurnet Point Capital

                          Deal Size : $287.0 million

                          Deal Type : Acquisition

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                          10

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Nuzyra (omadacycline tosylate) is a novel antibiotic which binds to the 30S ribosomal subunit and blocks protein synthesis, available for the treatment of community-acquired bacterial pneumonia and acute bacterial skin and skin structure infections.

                          Brand Name : Nuzyra

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          January 19, 2023

                          Lead Product(s) : Omadacycline

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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