Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Imetelstat
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Geron
Deal Size : Undisclosed
Deal Type : Partnership
Onco360 Chosen as Specialty Pharmacy Partner for Rytelo™ (Imetelstat)
Details : Onco360 partner by Geron for the distribution of Rytelo (imetelstat)l, telomerase inhibitor, approved for the treatment of adult patients with low to intermediate-risk myelodysplastic syndromes.
Product Name : Rytelo
Product Type : Oligonucleotide
Upfront Cash : Undisclosed
December 07, 2024
Lead Product(s) : Imetelstat
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Geron
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : Futibatinib
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Lytgobi (futibatinib) is a small molecule kinase inhibitor of FGFR. It has demonstrated anti-tumor activity by inhibiting FGFR phosphorylation and downstream signaling and decreased cell viability in cancer cell lines with FGFR alterations.
Product Name : Lytgobi
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
February 13, 2023
Lead Product(s) : Futibatinib
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Elacestrant
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Orserdu (elacestrant) is an estrogen receptor antagonist that binds to estrogen receptor-alpha (ERα). It inhibits 17β-estradiol mediated cell proliferation at concentrations inducing degradation of ERα protein mediated through proteasomal pathway.
Product Name : Orserdu
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
February 02, 2023
Lead Product(s) : Elacestrant
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Pirtobrutinib
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Jaypirca (pirtobrutinib) is a small molecule and a highly selective non-covalent inhibitor of Bruton’s tyrosine kinase (BTK). Its high selectivity has been associated with lower discontinuation rates due to adverse events and a lower incidence of atria...
Product Name : Jaypirca
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 02, 2023
Lead Product(s) : Pirtobrutinib
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Ivosidenib
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Servier
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : TIBSOVO® (ivosidenib), which is an isocitrate dehydrogenase-1 (IDH1) inhibitor indicated for patients with a susceptible IDH1 mutation as detected by an FDA-approved test with newly diagnosed acute myeloid leukemia (AML).
Product Name : Tibsovo
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
September 15, 2022
Lead Product(s) : Ivosidenib
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Servier
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Relugolix
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Myovant Sciences
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ORGOVYX® (relugolix), which is a gonadotropin-releasing hormone (GnRH) antagonist that is approved by the U.S. Food and Drug Administration (FDA) for the treatment of adult patients with advanced prostate cancer.
Product Name : Orgovyx
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
June 06, 2022
Lead Product(s) : Relugolix
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Myovant Sciences
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Pacritinib
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : CTI BioPharma Corp
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : FDA’s approval of VONJO (pacritinib) is based upon results of PERSIST-2 clinical trial indicate that 29% of myelofibrosis patients with baseline platelet levels of less than 50 x 109/L obtained spleen volume reductions of at least 35% during first six ...
Product Name : Vonjo
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 03, 2022
Lead Product(s) : Pacritinib
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : CTI BioPharma Corp
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Belumosudil
Therapeutic Area : Immunology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The FDA’s approval of REZUROCK comes as a result of the Phase II KD025-213 clinical trial which demonstrated 75% overall response rate after six cycles of therapy at a dose of 200mg orally once daily in patients with chronic GVHD disease.
Product Name : Rezurock
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
July 21, 2021
Lead Product(s) : Belumosudil
Therapeutic Area : Immunology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable