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India \/ Inapplicable"},{"orgOrder":0,"company":"Serum Institute of India","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"INDIA","productType":"Vaccine","year":"2022","type":"Inapplicable","leadProduct":"4-Valent HPV Vaccine","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase II\/ Phase III","graph3":"Serum Institute of India","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Serum Institute of India \/ Inapplicable","highestDevelopmentStatusID":"9","companyTruncated":"Serum Institute of India \/ Inapplicable"},{"orgOrder":0,"company":"Replimune","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2025","type":"Inapplicable","leadProduct":"Nivolumab","moa":"||Immunostimulant","graph1":"Oncology","graph2":"Phase II\/ Phase III","graph3":"Replimune","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intralesional Injection","sponsorNew":"Replimune \/ Inapplicable","highestDevelopmentStatusID":"9","companyTruncated":"Replimune \/ Inapplicable"},{"orgOrder":0,"company":"Ionctura","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"SWITZERLAND","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Roginolisib","moa":"PI3K delta","graph1":"Oncology","graph2":"Phase II\/ Phase III","graph3":"Ionctura","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Ionctura \/ Inapplicable","highestDevelopmentStatusID":"9","companyTruncated":"Ionctura \/ Inapplicable"},{"orgOrder":0,"company":"Ionctura","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"SWITZERLAND","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Roginolisib","moa":"PI3K delta","graph1":"Oncology","graph2":"Phase II\/ Phase III","graph3":"Ionctura","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Ionctura \/ Inapplicable","highestDevelopmentStatusID":"9","companyTruncated":"Ionctura \/ Inapplicable"},{"orgOrder":0,"company":"Ionctura","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"SWITZERLAND","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Roginolisib","moa":"PI3K delta","graph1":"Oncology","graph2":"Phase II\/ Phase III","graph3":"Ionctura","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Ionctura \/ Inapplicable","highestDevelopmentStatusID":"9","companyTruncated":"Ionctura \/ Inapplicable"},{"orgOrder":0,"company":"Ionctura","sponsor":"Syncona Limited","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"SWITZERLAND","productType":"Other Small Molecule","year":"2024","type":"Series B Financing","leadProduct":"Roginolisib","moa":"PI3K delta","graph1":"Oncology","graph2":"Phase II\/ Phase III","graph3":"Ionctura","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Ionctura \/ Syncona Limited","highestDevelopmentStatusID":"9","companyTruncated":"Ionctura \/ Syncona Limited"}]

    Find Oncology Drugs in Phase II/III Clinical Development

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                            01

                            Moleculin Biotech

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                            German Wound Congress
                            Not Confirmed

                            Moleculin Biotech

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                            German Wound Congress
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                            Lead Product(s) : Annamycin,Cytarabine

                            Therapeutic Area : Oncology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Moleculin Doses First Patient in Pivotal, Adaptive Phase 3 MIRACLE Trial

                            Details : Annamycin is a next-generation anthracycline, which is being evaluated in combination with cytarabine for the treatment of subjects with relapsed/refractory acute myeloid leukemia.

                            Product Name : AnnAraC

                            Product Type : Antibiotic

                            Upfront Cash : Inapplicable

                            April 01, 2025

                            Lead Product(s) : Annamycin,Cytarabine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            InnoCare Pharma

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                            German Wound Congress
                            Not Confirmed

                            InnoCare Pharma

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : ICP-248,Orelabrutinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            InnoCare Doses First Patient in Phase 3 trial of ICP-248 + Orelabrutinib for CLL/SLL

                            Details : ICP-248 is a novel, orally bioavailable, small molecule drug which is BCL2-selective inhibitor. It is currently being evaluated for the treatment of chronic lymphocytic leukemia.

                            Product Name : ICP-248

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            March 27, 2025

                            Lead Product(s) : ICP-248,Orelabrutinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Linnaeus Therapeutics

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                            German Wound Congress
                            Not Confirmed

                            Linnaeus Therapeutics

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : LNS8801

                            Therapeutic Area : Oncology

                            Study Phase : Phase II/ Phase III

                            Sponsor : National Cancer Institute

                            Deal Size : $2.0 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Linnaeus Wins Fourth NCI SBIR Grant, Total SBIR Funding Reaches $8.3M

                            Details : The fund will support the clinical development of its lead compound, LNS8801, which targets a G protein-coupled receptor (GPER), for the treatment of metastatic cutaneous melanoma.

                            Product Name : LNS8801

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            March 26, 2025

                            Lead Product(s) : LNS8801

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : National Cancer Institute

                            Deal Size : $2.0 million

                            Deal Type : Funding

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                            04

                            Innovent Biologics

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                            German Wound Congress
                            Not Confirmed

                            Innovent Biologics

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Fruquintinib,Sintilimab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Hutchmed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Innovent-HUTCHMED's FRUSICA-2 Study Hits Endpoint in Renal Cancer

                            Details : HMPL-013 (fruquintinib) in combination with IBI308 (sintilimab) is currently being evaluated for the treatment of advanced renal cell carcinoma.

                            Product Name : HMPL-013

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            March 18, 2025

                            Lead Product(s) : Fruquintinib,Sintilimab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Hutchmed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Eikon Therapeutics

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                            German Wound Congress
                            Not Confirmed

                            Eikon Therapeutics

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : EIK1001,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Lux Capital

                            Deal Size : $350.7 million

                            Deal Type : Series D Financing

                            DEALS_DEV arrow-down

                            Eikon Secures $350.7M Series D to Advance Clinical Programs, Future Pipeline

                            Details : The financing aims to advance the company's pipeline, which includes lead product EIK1001, a systemically administered co-agonist of toll-like receptors 7/8 now in a Phase III for advanced melanoma.

                            Product Name : EIK1001

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            February 26, 2025

                            Lead Product(s) : EIK1001,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Lux Capital

                            Deal Size : $350.7 million

                            Deal Type : Series D Financing

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                            06

                            InnoCare Pharma

                            China arrow
                            German Wound Congress
                            Not Confirmed

                            InnoCare Pharma

                            China arrow
                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Mesutoclax,Orelabrutinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            InnoCare Starts Phase III Trial of ICP-248 Plus Orelabrutinib for CLL/SLL

                            Details : ICP-248 is a B-cell lymphoma-2 (BCL2) inhibitor. It is being evaluated in combination with orelabrutinib for the treatment of chronic lymphocytic leukemia in China.

                            Product Name : ICP-248

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            February 17, 2025

                            Lead Product(s) : Mesutoclax,Orelabrutinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Moleculin Biotech

                            U.S.A arrow
                            German Wound Congress
                            Not Confirmed

                            Moleculin Biotech

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Annamycin,Cytarabine

                            Therapeutic Area : Oncology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Moleculin Gains FDA Support to Accelerate MIRACLE Trial for R/R AML Treatment

                            Details : Annamycin is a next-generation anthracycline, which is being evaluated in combination with cytarabine for the treatment of subjects with relapsed/refractory acute myeloid leukemia.

                            Product Name : AnnAraC

                            Product Type : Antibiotic

                            Upfront Cash : Inapplicable

                            February 13, 2025

                            Lead Product(s) : Annamycin,Cytarabine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Bicara Therapeutics

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                            German Wound Congress
                            Not Confirmed

                            Bicara Therapeutics

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Ficerafusp Alpha,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Bicara Begins Ficerafusp Alfa Phase 2/3 Trial in 1L R/M Head & Neck Cancer

                            Details : BCA101 (ficerafusp alfa) is a first-in-class bifunctional antibody which is being evaluated in combination with pembrolizumab in first line recurrent/metastatic head and neck squamous cell carcinoma.

                            Product Name : BCA101

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            February 11, 2025

                            Lead Product(s) : Ficerafusp Alpha,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Moleculin Biotech

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                            German Wound Congress
                            Not Confirmed

                            Moleculin Biotech

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Annamycin,Cytarabine

                            Therapeutic Area : Oncology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Moleculin Gains First EU Approval to Recruit for MIRACLE Phase 3 AML Trial

                            Details : Annamycin is a next-generation anthracycline, which is being evaluated in combination with cytarabine for the treatment of subjects with relapsed/refractory acute myeloid leukemia.

                            Product Name : AnnAraC

                            Product Type : Antibiotic

                            Upfront Cash : Inapplicable

                            February 11, 2025

                            Lead Product(s) : Annamycin,Cytarabine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Immunome

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                            German Wound Congress
                            Not Confirmed

                            Immunome

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                            Lead Product(s) : Varegacestat

                            Therapeutic Area : Oncology

                            Study Phase : Phase II/ Phase III

                            Sponsor : J.P. Morgan

                            Deal Size : $172.5 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Immunome Closes Upsized Public Offering, Underwriters’ Option Fully Exercised

                            Details : The proceeds will fund the clinical and preclinical development of pipeline assets, including AL102 (varegacestat), a gamma secretase and pan-Notch inhibitor, with potential antineoplastic activity.

                            Product Name : AL102

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            January 31, 2025

                            Lead Product(s) : Varegacestat

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : J.P. Morgan

                            Deal Size : $172.5 million

                            Deal Type : Public Offering

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