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Hoffmann-La Roche"},{"orgOrder":0,"company":"Laminar Pharma","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"2-Hydroxyoleic Acid","moa":"","graph1":"Oncology","graph2":"Phase II\/ Phase III","graph3":"Laminar Pharma","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Laminar Pharma \/ Not Applicable","highestDevelopmentStatusID":"9","companyTruncated":"Laminar Pharma \/ Not Applicable"},{"orgOrder":0,"company":"Fusion Pharma","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"Ac225-PSMA","moa":"","graph1":"Oncology","graph2":"Phase II\/ Phase III","graph3":"Fusion Pharma","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Fusion Pharma \/ Not Applicable","highestDevelopmentStatusID":"9","companyTruncated":"Fusion Pharma \/ Not Applicable"},{"orgOrder":0,"company":"Panbela Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"Ivospemin","moa":"","graph1":"Oncology","graph2":"Phase II\/ Phase III","graph3":"Panbela Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Panbela Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"9","companyTruncated":"Panbela Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Ionctura","sponsor":"Syncona Limited","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2024","type":"Series B Financing","leadProduct":"Roginolisib","moa":"","graph1":"Oncology","graph2":"Phase II\/ Phase III","graph3":"Ionctura","amount2":0.089999999999999997,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Oncology","amount2New":0.089999999999999997,"dosageForm":"","sponsorNew":"Ionctura \/ Syncona Limited","highestDevelopmentStatusID":"9","companyTruncated":"Ionctura \/ Syncona Limited"},{"orgOrder":0,"company":"Hutchmed","sponsor":"HengRui","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2024","type":"Collaboration","leadProduct":"Surufatinib","moa":"","graph1":"Oncology","graph2":"Phase II\/ Phase III","graph3":"Hutchmed","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Hutchmed \/ Hengrui","highestDevelopmentStatusID":"9","companyTruncated":"Hutchmed \/ Hengrui"}]

    Find Oncology Drugs in Phase II/III Clinical Development

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                            01

                            Immutep

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                            Immutep

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                            Lead Product(s) : Eftilagimod Alpha,Paclitaxel

                            Therapeutic Area : Oncology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Immutep Completes Patient Enrolment in Phase II AIPAC-003 Trial in Breast Cancer

                            Details : IMP321 (eftilagimod alpha) a soluble LAG-3 protein and MHC Class II agonist is being evaluated in combination with paclitaxel under evaluation for treatment of metastatic breast carcinoma.

                            Brand Name : IMP321

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            October 03, 2024

                            Lead Product(s) : Eftilagimod Alpha,Paclitaxel

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Gritstone bio

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                            Gritstone bio

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                            Lead Product(s) : GRT-C901,GRT-R902,Bevacizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Gritstone bio Reports Interim Phase 2 Data for GRANITE Immunotherapy in Colorectal Cancer

                            Details : Granite (GRT-C901/GRT-R902) is patient-specific neoantigen cancer vaccine. It is being evaluated for the treatment of front-line metastatic microsatellite stable colorectal cancer.

                            Brand Name : Granite

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            September 30, 2024

                            Lead Product(s) : GRT-C901,GRT-R902,Bevacizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            TC BioPharm

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                            TC BioPharm

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                            Lead Product(s) : Allogeneic Gamma Delta T Cell Therapy,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Undisclosed

                            Deal Size : Undisclosed

                            Deal Type : Public Offering

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                            TC BioPharm Announces Closing of Upsized $6.0 Million Public Offering

                            Details : The Company intends to use the net proceeds to support its upcoming clinical trial focusing on relapse/refractory Acute Myeloid Leukemia evaluating OmnImmune, an allogeneic gamma delta T cell product.

                            Brand Name : OmnImmune

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            August 28, 2024

                            Lead Product(s) : Allogeneic Gamma Delta T Cell Therapy,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Undisclosed

                            Deal Size : Undisclosed

                            Deal Type : Public Offering

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                            04

                            Compass Therapeutics

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                            Compass Therapeutics

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                            Lead Product(s) : CTX-009,Paclitaxel

                            Therapeutic Area : Oncology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Compass Completes Enrollment in COMPANION-002 Study of CTX-009 in Biliary Tract Cancer

                            Details : CTX-009 is a bispecific DLL4/VEGF-A antibody, it is being evaluated in combination with paclitaxel for the treatment of patients with metastatic or locally advanced biliary tract tumors.

                            Brand Name : CTX-009

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            August 06, 2024

                            Lead Product(s) : CTX-009,Paclitaxel

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            ALX Oncology

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                            ALX Oncology

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                            Lead Product(s) : Evorpacept,Trastuzumab,Ramucirumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            ALX Reports Phase 2 Data Showing Evorpacept Improves HER2-Positive Gastric Cancer Response

                            Details : ALX148 (evorpacept) is a next generation CD47 blocker, which is being investigated in combination with trastuzumab in patients with HER2-positive gastric/gastroesophageal junction (“GEJ”) cancer.

                            Brand Name : ALX148

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            July 31, 2024

                            Lead Product(s) : Evorpacept,Trastuzumab,Ramucirumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Kazia Therapeutics

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                            Kazia Therapeutics

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                            Lead Product(s) : Paxalisib

                            Therapeutic Area : Oncology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Kazia Therapeutics Announces Phase II/III Results for Paxalisib in Glioblastoma

                            Details : GDC-0084 (paxalisib) is a PI3K/mTOR inhibitor small molecule drug candidate, which is being evaluated for the treatment of newly diagnosed glioblastoma.

                            Brand Name : GDC-0084

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            July 10, 2024

                            Lead Product(s) : Paxalisib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Iteos Therapeutics

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                            Iteos Therapeutics

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                            Lead Product(s) : Belrestotug,Dostarlimab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II/ Phase III

                            Sponsor : GSK

                            Deal Size : $2,075.0 million

                            Deal Type : Collaboration

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                            iTeos Doses First Patient in GALAXIES Lung-301 Phase 3, Earns $35M from GSK

                            Details : The collaboration aims to advance the clinical development of late-stage product EOS-448 (belrestotug) in combination with Dostarlimab for the treatment of PD-L1 high Non-small Cell Lung Cancer.

                            Brand Name : EOS-448

                            Molecule Type : Large molecule

                            Upfront Cash : $625.0 million

                            July 08, 2024

                            Lead Product(s) : Belrestotug,Dostarlimab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : GSK

                            Deal Size : $2,075.0 million

                            Deal Type : Collaboration

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                            08

                            Genentech

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                            Genentech

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                            Lead Product(s) : Tiragolumab,Atezolizumab,Pemetrexed

                            Therapeutic Area : Oncology

                            Study Phase : Phase II/ Phase III

                            Sponsor : F. Hoffmann-La Roche

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Genentech Updates on Phase II/III SKYSCRAPER-06 Study in Metastatic NSCLC

                            Details : MTIG7192A (tiragolumab) is an antibody, whch selectively binds to TIGIT. It is currently being evaluated for the treatment of unresectable or metastatic non-squamous non-small cell lung cancer.

                            Brand Name : MTIG7192A

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            July 04, 2024

                            Lead Product(s) : Tiragolumab,Atezolizumab,Pemetrexed

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : F. Hoffmann-La Roche

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Panbela Therapeutics

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                            Panbela Therapeutics

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                            Lead Product(s) : Ivospemin,Paclitaxel,Gemcitabine

                            Therapeutic Area : Oncology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Panbela Reports Third Safety Review Recommending Continuation of ASPIRE Trial

                            Details : SBP-101 (ivospemin) is a small molecule AMD1/ODC1 inhibitor, being evaluated in combination with gemcitabine & nab-paclitaxel for the treatment of metastatic pancreatic ductal adenocarcinoma.

                            Brand Name : SBP-101

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            June 24, 2024

                            Lead Product(s) : Ivospemin,Paclitaxel,Gemcitabine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            Ionctura

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                            Lead Product(s) : Roginolisib

                            Therapeutic Area : Oncology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Syncona Limited

                            Deal Size : $85.9 million

                            Deal Type : Series B Financing

                            DEALS_DEV arrow-down

                            iOnctura Announces €80 Million Series B Financing to Progress Pipeline Through Phase II

                            Details : The financing will be used to accelerate the development of IOA-244 (roginolisib), which is being evaluated in the mid-stage clinical trial studies for the treatment of uveal melanoma.

                            Brand Name : IOA-244

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            June 20, 2024

                            Lead Product(s) : Roginolisib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Syncona Limited

                            Deal Size : $85.9 million

                            Deal Type : Series B Financing

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