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therapy","year":"2024","type":"Partnership","leadProduct":"MGB-001","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Matica Biotechnology","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Matica Biotechnology \/ Mongoose Bio","highestDevelopmentStatusID":"4","companyTruncated":"Matica Biotechnology \/ Mongoose Bio"},{"orgOrder":0,"company":"Isotope Technologies Munich","sponsor":"Technical University of Munich","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"GERMANY","productType":"Large molecule","year":"2024","type":"Agreement","leadProduct":"Radiopharmaceutical","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Isotope Technologies Munich","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Isotope Technologies Munich \/ Technical University of Munich","highestDevelopmentStatusID":"4","companyTruncated":"Isotope Technologies Munich \/ Technical University of Munich"},{"orgOrder":0,"company":"Pluri","sponsor":"Bar-Ilan University","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"ISRAEL","productType":"Cell and Gene therapy","year":"2024","type":"Collaboration","leadProduct":"MAIT Cell-based Therapy","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Pluri","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Pluri \/ Bar-Ilan University","highestDevelopmentStatusID":"4","companyTruncated":"Pluri \/ Bar-Ilan University"},{"orgOrder":0,"company":"GlycoMimetics","sponsor":"Crescent Biopharma","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2024","type":"Merger","leadProduct":"CR-001","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"GlycoMimetics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"GlycoMimetics \/ Crescent Biopharma","highestDevelopmentStatusID":"4","companyTruncated":"GlycoMimetics \/ Crescent Biopharma"},{"orgOrder":0,"company":"Aileron Therapeutics","sponsor":"Advancium Health","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2024","type":"Acquisition","leadProduct":"Sulanemadlin","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Aileron Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Aileron Therapeutics \/ Advancium Health","highestDevelopmentStatusID":"4","companyTruncated":"Aileron Therapeutics \/ Advancium Health"},{"orgOrder":0,"company":"Valo Therapeutics","sponsor":"Lisata Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"UNITED KINGDOM","productType":"Peptide","year":"2024","type":"Collaboration","leadProduct":"Certepetide","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Valo Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Valo Therapeutics \/ Lisata Therapeutics","highestDevelopmentStatusID":"4","companyTruncated":"Valo Therapeutics \/ Lisata Therapeutics"},{"orgOrder":0,"company":"Alteogen","sponsor":"Daiichi Sankyo","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"SOUTH KOREA","productType":"Large molecule","year":"2024","type":"Licensing Agreement","leadProduct":"Trastuzumab Deruxtecan","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Alteogen","amount2":0.29999999999999999,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0.29999999999999999,"dosageForm":"","sponsorNew":"Alteogen \/ Daiichi Sankyo","highestDevelopmentStatusID":"4","companyTruncated":"Alteogen \/ Daiichi Sankyo"},{"orgOrder":0,"company":"AtomVie Global Radiopharma","sponsor":"Radiopharm Ventures","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2024","type":"Agreement","leadProduct":"177Lu-BetaBart","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"AtomVie Global Radiopharma","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"AtomVie Global Radiopharma \/ Radiopharm Ventures","highestDevelopmentStatusID":"4","companyTruncated":"AtomVie Global Radiopharma \/ Radiopharm Ventures"},{"orgOrder":0,"company":"Entero Therapeutics","sponsor":"Journey Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2024","type":"Merger","leadProduct":"Nano-Immunoconjugate","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Entero Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Entero Therapeutics \/ Journey Therapeutics","highestDevelopmentStatusID":"4","companyTruncated":"Entero Therapeutics \/ Journey Therapeutics"},{"orgOrder":0,"company":"KisoJi Biotechnology","sponsor":"Cancer Research UK","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"CANADA","productType":"Large molecule","year":"2024","type":"Collaboration","leadProduct":"KJ-103","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"KisoJi Biotechnology","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"KisoJi Biotechnology \/ Cancer Research UK","highestDevelopmentStatusID":"4","companyTruncated":"KisoJi Biotechnology \/ Cancer Research UK"},{"orgOrder":0,"company":"Sterling Pharma Solutions","sponsor":"GlycoNex","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"UNITED KINGDOM","productType":"Large molecule","year":"2024","type":"Agreement","leadProduct":"GNX102-ADC","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Sterling Pharma Solutions","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Sterling Pharma Solutions \/ GlycoNex","highestDevelopmentStatusID":"4","companyTruncated":"Sterling Pharma Solutions \/ GlycoNex"},{"orgOrder":0,"company":"Reverb Therapeutics","sponsor":"Royalmount Laboratories","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"CANADA","productType":"Large molecule","year":"2024","type":"Collaboration","leadProduct":"Bispecific Antibody-based Therapy","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Reverb Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Reverb Therapeutics \/ Royalmount Laboratories","highestDevelopmentStatusID":"4","companyTruncated":"Reverb Therapeutics \/ Royalmount Laboratories"},{"orgOrder":0,"company":"3B Pharmaceuticals","sponsor":"ARTBIO","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"GERMANY","productType":"Peptide","year":"2024","type":"Licensing Agreement","leadProduct":"212Pb-based Alpha Radioligand Therapy","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"3B Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"3B Pharmaceuticals \/ ARTBIO","highestDevelopmentStatusID":"4","companyTruncated":"3B Pharmaceuticals \/ ARTBIO"},{"orgOrder":0,"company":"Peak Bio","sponsor":"Akari Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2024","type":"Merger","leadProduct":"ADC-based Therapy","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Peak Bio","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Peak Bio \/ Akari Therapeutics","highestDevelopmentStatusID":"4","companyTruncated":"Peak Bio \/ Akari Therapeutics"},{"orgOrder":0,"company":"ATB Therapeutics","sponsor":"EQT Life Sciences","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"BELGIUM","productType":"Large molecule","year":"2024","type":"Series A Financing","leadProduct":"Antibody","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"ATB Therapeutics","amount2":0.059999999999999998,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0.059999999999999998,"dosageForm":"","sponsorNew":"ATB Therapeutics \/ EQT Life Sciences","highestDevelopmentStatusID":"4","companyTruncated":"ATB Therapeutics \/ EQT Life Sciences"},{"orgOrder":0,"company":"Ratio Therapeutics","sponsor":"Novartis Pharmaceuticals Corporation","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2024","type":"Licensing Agreement","leadProduct":"Radiopharmaceutical Therapy","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Ratio Therapeutics","amount2":0.75,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0.75,"dosageForm":"","sponsorNew":"Ratio Therapeutics \/ Novartis Pharmaceuticals Corporation","highestDevelopmentStatusID":"4","companyTruncated":"Ratio Therapeutics \/ Novartis Pharmaceuticals Corporation"},{"orgOrder":0,"company":"Alligator Bioscience","sponsor":"Orion Corporation","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"SWEDEN","productType":"Large molecule","year":"2024","type":"Collaboration","leadProduct":"Bispecific Antibody","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Alligator Bioscience","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Alligator Bioscience \/ Orion Corporation","highestDevelopmentStatusID":"4","companyTruncated":"Alligator Bioscience \/ Orion Corporation"},{"orgOrder":0,"company":"DP Technology","sponsor":"Lepu Biopharma","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"CHINA","productType":"Large molecule","year":"2024","type":"Collaboration","leadProduct":"ADC-based Therapy","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"DP Technology","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"DP Technology \/ Lepu Biopharma","highestDevelopmentStatusID":"4","companyTruncated":"DP Technology \/ Lepu Biopharma"},{"orgOrder":0,"company":"NorthStar Medical Radioisotopes","sponsor":"Cellectar","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2024","type":"Agreement","leadProduct":"CLR 121225","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"NorthStar Medical Radioisotopes","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"NorthStar Medical Radioisotopes \/ Cellectar","highestDevelopmentStatusID":"4","companyTruncated":"NorthStar Medical Radioisotopes \/ Cellectar"},{"orgOrder":0,"company":"PrimeFour Therapeutics","sponsor":"Transposon Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2024","type":"Acquisition","leadProduct":"Nucleoside-based Chemotherapy","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"PrimeFour Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"PrimeFour Therapeutics \/ Transposon Therapeutics","highestDevelopmentStatusID":"4","companyTruncated":"PrimeFour Therapeutics \/ Transposon Therapeutics"},{"orgOrder":0,"company":"Rakovina Therapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"CANADA","productType":"Small molecule","year":"2024","type":"Private Placement","leadProduct":"KT-3000","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Rakovina 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Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Carisma Therapeutics \/ Moderna Therapeutics","highestDevelopmentStatusID":"4","companyTruncated":"Carisma Therapeutics \/ Moderna Therapeutics"},{"orgOrder":0,"company":"Ideaya Biosciences","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"IDE034","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Ideaya Biosciences","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Ideaya Biosciences \/ Not Applicable","highestDevelopmentStatusID":"4","companyTruncated":"Ideaya Biosciences \/ Not Applicable"},{"orgOrder":0,"company":"Siren Biotechnology","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Cell and Gene therapy","year":"2024","type":"Not Applicable","leadProduct":"SRN-101","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Siren Biotechnology","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Siren Biotechnology \/ Not Applicable","highestDevelopmentStatusID":"4","companyTruncated":"Siren Biotechnology \/ Not Applicable"},{"orgOrder":0,"company":"Trogenix","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Undisclosed","year":"2024","type":"Not Applicable","leadProduct":"Undisclosed","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Trogenix","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Trogenix \/ Not 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Ltd","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2024","type":"Collaboration","leadProduct":"Humabody Based Radiopharmaceutical","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Oranomed","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Oranomed \/ Crescendo Biologics Ltd","highestDevelopmentStatusID":"4","companyTruncated":"Oranomed \/ Crescendo Biologics Ltd"},{"orgOrder":0,"company":"Molecular Partners","sponsor":"Oranomed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"MP0712","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Molecular Partners","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Molecular Partners \/ Oranomed","highestDevelopmentStatusID":"4","companyTruncated":"Molecular Partners \/ Oranomed"},{"orgOrder":0,"company":"Biomunex Pharmaceutical","sponsor":"Ipsen","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2024","type":"Licensing Agreement","leadProduct":"BMX-502","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Biomunex Pharmaceutical","amount2":0.60999999999999999,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0.60999999999999999,"dosageForm":"","sponsorNew":"Biomunex Pharmaceutical \/ Ipsen","highestDevelopmentStatusID":"4","companyTruncated":"Biomunex Pharmaceutical \/ Ipsen"},{"orgOrder":0,"company":"Scancell","sponsor":"Genmab","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2024","type":"Licensing Agreement","leadProduct":"Monoclonal Antibody","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Scancell","amount2":0.63,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0.63,"dosageForm":"","sponsorNew":"Scancell \/ Genmab","highestDevelopmentStatusID":"4","companyTruncated":"Scancell \/ Genmab"},{"orgOrder":0,"company":"WuXi Biologics","sponsor":"Aadi Bioscience","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2024","type":"Licensing Agreement","leadProduct":"PTK7-CPT113","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"WuXi Biologics","amount2":0.84999999999999998,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0.84999999999999998,"dosageForm":"","sponsorNew":"WuXi Biologics \/ Aadi Bioscience","highestDevelopmentStatusID":"4","companyTruncated":"WuXi Biologics \/ Aadi Bioscience"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : RVU120

                          Therapeutic Area : Oncology

                          Study Phase : Preclinical

                          Sponsor : Ryvu Therapeutics

                          Deal Size : $1.0 million

                          Deal Type : Agreement

                          Details : RVU120 is a selective, first-in-class dual CDK8/CDK19 kinase inhibitor that has shown signs of clinical activity in treated patients, as well as efficacy in numerous in vitro and in vivo models of hematologic malignancies and solid tumors.

                          Brand Name : RVU120

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          July 06, 2023

                          Lead Product(s) : RVU120

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Ryvu Therapeutics

                          Deal Size : $1.0 million

                          Deal Type : Agreement

                          Polpharma CB

                          02

                          Details : IMGN632 (pivekimab sunirine) is a CD123-targeting ADC in clinical development for hematological malignancies, including blastic plasmacytoid dendritic cell neoplasm (BPDCN), acute myeloid leukemia (AML), and other CD123+ hematologic malignancies.

                          Brand Name : IMGN632

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          December 09, 2022

                          Lead Product(s) : Pivekimab Sunirine,Magrolimab

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Gilead Sciences

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

                          Immunogen

                          03

                          Lead Product(s) : Mesenchymal Stem Cells-based Therapy

                          Therapeutic Area : Oncology

                          Study Phase : Preclinical

                          Sponsor : Rohto Pharmaceutical

                          Deal Size : Undisclosed

                          Deal Type : Partnership

                          Details : The joint venture will be settled in the Haikou National High-tech Zone of south China's Hainan Province, and will focus on research in regenerative medicine and cell culture medium, mesenchymal stem cells-based therapies, as well as related commercial o...

                          Brand Name : Undisclosed

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          June 24, 2022

                          Lead Product(s) : Mesenchymal Stem Cells-based Therapy

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Rohto Pharmaceutical

                          Deal Size : Undisclosed

                          Deal Type : Partnership

                          Bloomage Company Banner

                          04

                          Lead Product(s) : OXL001

                          Therapeutic Area : Oncology

                          Study Phase : Preclinical

                          Sponsor : Oxilio

                          Deal Size : Undisclosed

                          Deal Type : Agreement

                          Details : Oxilio has since progressed the product and now signed a significant service contract with Quotient Sciences, a drug development and manufacturing accelerator, to support the formulation development and preparation of clinical trials for OXL001.

                          Brand Name : OXL001

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          February 18, 2022

                          Lead Product(s) : OXL001

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Oxilio

                          Deal Size : Undisclosed

                          Deal Type : Agreement

                          Quotient

                          05

                          Details : Poseida will apply licensed UniDab binders, which possess significant advantages over traditional single chain variable antibody fragment (scFv) binders, to develop its next generation CAR-T therapies. Targets were not disclosed.

                          Brand Name : Undisclosed

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          November 23, 2020

                          Lead Product(s) : CAR-T therapies

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Amgen Inc

                          Deal Size : $250.0 million

                          Deal Type : Licensing Agreement

                          Abbvie Company Banner

                          06

                          Lead Product(s) : Denileukin Diftitox,Anti-PD-1 agent

                          Therapeutic Area : Oncology

                          Study Phase : Preclinical

                          Sponsor : Eisai

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Details : Combination of E7777 with an anti-PD-1 agent provided clear benefit both in terms of tumor growth control, and a highly significant improvement in overall survival.

                          Brand Name : E7777

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          November 09, 2020

                          Lead Product(s) : Denileukin Diftitox,Anti-PD-1 agent

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Eisai

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Dr Reddy Company Banner

                          07

                          Lead Product(s) : K-NK004,Isatuximab-irfc

                          Therapeutic Area : Oncology

                          Study Phase : Preclinical

                          Sponsor : Sanofi

                          Deal Size : $359.0 million

                          Deal Type : Acquisition

                          Details : Kiadis’ proprietary platform is based on allogeneic or ‘off-the-shelf' NK cells from a healthy donor. NK cells seek and identify malignant cancer cells and have broad application across various tumor types.

                          Brand Name : K-NK004

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          November 02, 2020

                          Lead Product(s) : K-NK004,Isatuximab-irfc

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Sanofi

                          Deal Size : $359.0 million

                          Deal Type : Acquisition

                          Sanofi Company Banner

                          08

                          Lead Product(s) : K-NK cells,Isatuximab-irfc

                          Therapeutic Area : Oncology

                          Study Phase : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Details : The article describes the synergy of mbIL21 expanded NK cells (FC21-NK) modified with a CD38 gene knockout together with an anti-CD38 monoclonal antibody (mAb) for enhanced killing of multiple myeloma cells.

                          Brand Name : K-NK004

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          July 22, 2020

                          Lead Product(s) : K-NK cells,Isatuximab-irfc

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Sanofi Company Banner

                          09

                          Lead Product(s) : K-NK004,Isatuximab-irfc

                          Therapeutic Area : Oncology

                          Study Phase : Preclinical

                          Sponsor : Sanofi

                          Deal Size : $986.0 million

                          Deal Type : Collaboration

                          Details : Combination of Kiadis’ CD38 knock out K-NK cells with Sanofi’s anti-CD38 antibody Sarclisa® enables optimal tumor cell killing, and offers a potential first-in-class treatment for patients with multiple myeloma.

                          Brand Name : K-NK004

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : $20.4 million

                          July 08, 2020

                          Lead Product(s) : K-NK004,Isatuximab-irfc

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Sanofi

                          Deal Size : $986.0 million

                          Deal Type : Collaboration

                          Sanofi Company Banner

                          10

                          Details : Next Generation FRα- Targeting ADC engineered to maximize potential clinical benefit for patients with lower FRα expression. potent anti-tumor activity exhibited in ovarian cancer and other tumor types regardless of FRα expression level.

                          Brand Name : IMGN151

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          June 22, 2020

                          Lead Product(s) : IMGN151

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Immunogen