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Find Clinical Drug Pipeline Developments & Deals by ONK Therapeutics

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The partnership aims to explore the combination of ONK’s ONKT105, CISH + TGFβR2 double knock-out (KO), sIL-15 knock-in (KI) allogeneic NK cell therapy with NAYA’s GPC3-targeted NY-303 FLEX-NK™ bispecific antibody for the treatment of cancer.

                          Brand Name : ONKT105

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          December 06, 2023

                          Lead Product(s) : ONKT105,NY-303

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Naya Biosciences

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          02

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : ONKT102 is the company’s most advanced program, and is being advanced towards clinical development as a potential treatment for patients with relapsed or refractory multiple myeloma (MM).

                          Brand Name : ONKT102

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          August 29, 2022

                          Lead Product(s) : ONKT102

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The financing will enable ONK to maintain its strong momentum as it advances pre-clinical programs including ONKT102, through comprehensive IND-enabling studies, including in-vivo proof-of-concept models across multiple programs.

                          Brand Name : ONKT102

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          January 06, 2022

                          Lead Product(s) : ONKT102

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Sponsor : Acorn Bioventures

                          Deal Size : $21.5 million

                          Deal Type : Series A Financing

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                          04

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : ONKT102 combines an optimized affinity CD38 CAR and a TRAILv targeting DR5, intended for the treatment of patients with relapsed/refractory multiple myeloma.

                          Brand Name : ONKT102

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          September 09, 2021

                          Lead Product(s) : ONKT102

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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