Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : OQL025
Therapeutic Area : Dermatology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
OnQuality Gets FDA Clearance for IND Application Of OQL025 for Acneiform Rash
Details : OQL025 is a first-in disease topical agent to treat moderate to severe acneiform rash in patients receiving EGFR inhibitors.
Brand Name : OQL025
Molecule Type : Undisclosed
Upfront Cash : Not Applicable
January 04, 2024
Lead Product(s) : OQL025
Therapeutic Area : Dermatology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : OQL051
Therapeutic Area : Gastroenterology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : OQL051 sia first-in-disease, oral, gut-restricted CDK4/6 inhibitor – is designed to prevent the development of CID in patients receiving cytotoxic chemotherapies. The drug works by temporarily arresting the rapidly dividing intestinal mucosal cells in ...
Brand Name : OQL051
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 06, 2023
Lead Product(s) : OQL051
Therapeutic Area : Gastroenterology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : OQL036
Therapeutic Area : Dermatology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
OnQuality Announces FDA Clearance of IND Application for OQL036
Details : OQL036 is a novel topical agent that locally alleviates the toxicities induced by capecitabine metabolites, and reduces the inflammation associated with capecitabine-induced hand-foot syndrome (HFS).
Brand Name : OQL036
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 28, 2023
Lead Product(s) : OQL036
Therapeutic Area : Dermatology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : OQL011
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
OnQuality Pharmaceuticals Expands Part 2 of the NOVA-II Phase 2 Clinical Trial to China and India
Details : OQL011 is a proprietary ointment that locally activates VEGF downstream signaling pathways to treat HFSR in cancer patients. OQL011 improves or restores VEGF signaling in cell viability and functionality to alleviate HFSR symptoms.
Brand Name : OQL011
Molecule Type : Large molecule
Upfront Cash : Not Applicable
January 05, 2023
Lead Product(s) : OQL011
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : OQL011
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NOVA-II trial is evaluating OQL011, a topical ointment for the management of Hand-Foot Skin Reaction (HFSR) in cancer patients receiving vascular endothelial growth factor receptor inhibitor(s) (VEGFRi) as part of their treatment.
Brand Name : OQL011
Molecule Type : Large molecule
Upfront Cash : Not Applicable
November 08, 2022
Lead Product(s) : OQL011
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : OQL051
Therapeutic Area : Gastroenterology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Preclinical data from in vitro and in vivo experiments showing that OQL051, a gut-restricted CDK4/6 inhibitor, had significant efficacy in protecting gastrointestinal tissues from damage and decreasing diarrhea caused by chemotherapy for prevention of CI...
Brand Name : OQL051
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 08, 2022
Lead Product(s) : OQL051
Therapeutic Area : Gastroenterology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : OQL011
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : OnQuality will present an update on its NOVA-II Phase 2 clinical trial investigating OQL011, a proprietary ointment designed to treat HFSR, including findings from Part 1 and plans for Part 2 of the study.
Brand Name : OQL011
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 14, 2022
Lead Product(s) : OQL011
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : OQL011
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Part 1 of Phase 2 NOVA-II clinical trial evaluating OQL011 met the company's primary safety and efficacy expectations, after the favorable results OnQuality is all set to begin Part 2 of NOVA-II in Q1 2022.
Brand Name : OQL011
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 04, 2022
Lead Product(s) : OQL011
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : OQL011
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : Shiyu Capital
Deal Size : $35.0 million
Deal Type : Series A Financing
OnQuality Pharmaceuticals Announces Closing of $35 Million Series A and A+ Financing
Details : Proceeds from the financing will support the Phase II clinical trial of the company's leading compound OQL011, as well as multiple additional targeted cancer supportive care programs anticipated to enter different phases of clinical development over the ...
Brand Name : OQL011
Molecule Type : Undisclosed
Upfront Cash : Undisclosed
March 31, 2021
Lead Product(s) : OQL011
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : Shiyu Capital
Deal Size : $35.0 million
Deal Type : Series A Financing
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