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Therapeutix","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Axitinib","moa":"VEGFR","graph1":"Ophthalmology","graph2":"Phase I","graph3":"Ocular Therapeutix","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Intravitreal Implant","sponsorNew":"Ocular Therapeutix \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Ocular Therapeutix \/ Inapplicable"},{"orgOrder":0,"company":"Ocugen","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Protein","year":"2025","type":"Inapplicable","leadProduct":"OCU200","moa":"Undisclosed","graph1":"Ophthalmology","graph2":"Phase I","graph3":"Ocugen","amount2":0,"highestDevelopmentShortName":"Ph 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Nanomerics","highestDevelopmentStatusID":"6","companyTruncated":"Quotient Sciences \/ Nanomerics"},{"orgOrder":0,"company":"Nanomerics","sponsor":"Quotient Sciences","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"UNITED KINGDOM","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"OC134","moa":"Undisclosed","graph1":"Ophthalmology","graph2":"Phase I","graph3":"Nanomerics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Nanomerics \/ Quotient Sciences","highestDevelopmentStatusID":"6","companyTruncated":"Nanomerics \/ Quotient Sciences"}]

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                          01

                          Lead Product(s) : OC134

                          Therapeutic Area : Ophthalmology

                          Study Phase : Phase I

                          Sponsor : Nanomerics

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : OC134 is an eye drop medicine candidate indicated for the topical treatment of moderate to severe allergic conjunctivitis, a condition for which a suitable non-steroidal topical ocular treatment.

                          Product Name : OC134

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          December 11, 2024

                          Lead Product(s) : OC134

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase I

                          Sponsor : Nanomerics

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Quotient

                          02

                          Lead Product(s) : Laquinimod

                          Therapeutic Area : Ophthalmology

                          Study Phase : Phase I

                          Sponsor : Active Biotech

                          Deal Size : Undisclosed

                          Deal Type : Agreement

                          Details : Through the agreement, Active Biotech will get the material for the clinical development of the eye-drop formulation of ABR-215062 (laquinimod), which is used for the treatment of non-infectious non-anterior uveitis.

                          Product Name : ABR-215062

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          April 02, 2021

                          Lead Product(s) : Laquinimod

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase I

                          Sponsor : Active Biotech

                          Deal Size : Undisclosed

                          Deal Type : Agreement

                          Famar

                          03

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                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details : The combined company will focus on the development of TH103, a fully humanized, recombinant fusion protein, for patients with neovascular age-related macular degeneration.

                          Product Name : TH103

                          Product Type : Protein

                          Upfront Cash : Undisclosed

                          March 18, 2025

                          Lead Product(s) : TH103

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase I

                          Sponsor : Kalaris Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Merger

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                          04

                          AAN
                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details : OCU200 is a recombinant fusion protein that consists tumstatin, anti-VEGF agent and transferrin, which targets the drug to the choroid and retina. It is being developed for diabetic macular edema.

                          Product Name : OCU200

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          March 18, 2025

                          Lead Product(s) : OCU200

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          AAN
                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details : OC134 is an eye drop medicine candidate indicated for the topical treatment of moderate to severe allergic conjunctivitis, a condition for which a suitable non-steroidal topical ocular treatment.

                          Product Name : OC134

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          March 10, 2025

                          Lead Product(s) : OC134

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase I

                          Sponsor : Quotient Sciences

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          AAN
                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details : OCU200 is a recombinant fusion protein that consists tumstatin, anti-VEGF agent and transferrin, which targets the drug to the choroid and retina. It is being developed for diabetic macular edema.

                          Product Name : OCU200

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          January 16, 2025

                          Lead Product(s) : OCU200

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          AAN
                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details : SOM-401 (kamuvudine-8) is a novel, first-in-class, dual inflammasome inhibitor, being investigated for geographic atrophy (GA), the most serious form of dry age-related macular degeneration.

                          Product Name : SOM-401

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          January 15, 2025

                          Lead Product(s) : Kamuvudine-8

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          AAN
                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details : OC134 is an eye drop medicine candidate indicated for the topical treatment of moderate to severe allergic conjunctivitis, a condition for which a suitable non-steroidal topical ocular treatment.

                          Product Name : OC134

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          January 09, 2025

                          Lead Product(s) : OC134

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase I

                          Sponsor : Quotient Sciences

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          AAN
                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details :

                          Product Name : DF-003

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          December 19, 2024

                          Lead Product(s) : 8-Bromo-pet-cyclic gmps

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase I

                          Sponsor : NIAID

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          10

                          AAN
                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details : OC134 is an eye drop medicine candidate indicated for the topical treatment of moderate to severe allergic conjunctivitis, a condition for which a suitable non-steroidal topical ocular treatment.

                          Product Name : OC134

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          December 11, 2024

                          Lead Product(s) : OC134

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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