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                            Lead Product(s) : Vorolanib

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase II

                            Sponsor : J.P. Morgan

                            Deal Size : $161.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            EyePoint Closes Upsized Offering And Option for Additional Shares

                            Details : The intends to use the net proceeds from the offering to advance clinical development of Duravyu (Vorolanib) for wet age related macular degeneration (wet AMD) and diabetic macular edema.

                            Brand Name : Duravyu

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            October 31, 2024

                            Lead Product(s) : Vorolanib

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase II

                            Sponsor : J.P. Morgan

                            Deal Size : $161.0 million

                            Deal Type : Public Offering

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                            02

                            EyePoint Pharmaceuticals

                            U.S.A arrow
                            Medlab Asia & Asia Health
                            Not Confirmed

                            EyePoint Pharmaceuticals

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                            Medlab Asia & Asia Health
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Vorolanib

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            EyePoint Reports Positive 16-Week Data for DURAVYU in Phase 2 Study

                            Details : Duravyu (vorolanib) is a selective TKI formulated in a solid bioerodible insert. It is under development for the treatment of non-proliferative diabetic macular edema.

                            Brand Name : Duravyu

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 28, 2024

                            Lead Product(s) : Vorolanib

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Opus Genetics

                            U.S.A arrow
                            Medlab Asia & Asia Health
                            Not Confirmed

                            Opus Genetics

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                            Medlab Asia & Asia Health
                            Not Confirmed
                            • fda
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                            Lead Product(s) : APX3330

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase II

                            Sponsor : Ocuphire Pharma

                            Deal Size : Undisclosed

                            Deal Type : Merger

                            DEALS_DEV arrow-down

                            Ocuphire Pharma Announces Acquisition of Opus Genetics

                            Details : The acquisition creates a leading, clinical-stage company focused on developing gene therapies, including APX3330, an oral small-molecule inhibitor of Ref-1 for non-proliferative diabetic retinopathy.

                            Brand Name : APX3330

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            October 22, 2024

                            Lead Product(s) : APX3330

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase II

                            Sponsor : Ocuphire Pharma

                            Deal Size : Undisclosed

                            Deal Type : Merger

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                            04

                            Clearside Biomedical

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                            Medlab Asia & Asia Health
                            Not Confirmed

                            Clearside Biomedical

                            U.S.A arrow
                            Medlab Asia & Asia Health
                            Not Confirmed
                            • fda
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                            • WHO-GMP
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                            Lead Product(s) : Axitinib

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Clearside Announces Positive Results in ODYSSEY Phase 2b Trial For Wet AMD

                            Details : CLS-AX (axitinib injectable suspension) is a tyrosine kinase inhibitor (TKI), is under Phase 2b clinical trial for the treatment of wet AMD.

                            Brand Name : CLS-AX

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 09, 2024

                            Lead Product(s) : Axitinib

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Aviceda Therapeutics

                            U.S.A arrow
                            Medlab Asia & Asia Health
                            Not Confirmed

                            Aviceda Therapeutics

                            U.S.A arrow
                            Medlab Asia & Asia Health
                            Not Confirmed
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                            Lead Product(s) : AVD-104

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Aviceda Completes Enrollment in Phase 2b SIGLEC Study for Geographic Atrophy

                            Details : AVD-104 is a novel small molecule, neutrophil/macrophage activation inhibitor, being evaluated for the treatment of patients with geographic atrophy secondary to macular degeneration.

                            Brand Name : AVD-104

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 24, 2024

                            Lead Product(s) : AVD-104

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Clearside Biomedical

                            U.S.A arrow
                            Medlab Asia & Asia Health
                            Not Confirmed

                            Clearside Biomedical

                            U.S.A arrow
                            Medlab Asia & Asia Health
                            Not Confirmed
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                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Axitinib

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Clearside Biomedical Completes ODYSSEY Phase 2b Trial for CLS-AX in Wet AMD

                            Details : CLS-AX (axitinib injectable suspension) is a tyrosine kinase inhibitor (TKI), is under Phase 2b clinical trial for the treatment of wet AMD.

                            Brand Name : CLS-AX

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            August 27, 2024

                            Lead Product(s) : Axitinib

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            OKYO Pharma

                            United Kingdom arrow
                            Medlab Asia & Asia Health
                            Not Confirmed

                            OKYO Pharma

                            United Kingdom arrow
                            Medlab Asia & Asia Health
                            Not Confirmed
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                            Lead Product(s) : OK-101

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            OKYO Pharma Reports Positive Data from OK-101 Phase 2 Trial in Dry Eye Disease

                            Details : OK-101 is a lipid conjugated chemerin peptide agonist of the ChemR23 G-protein coupled receptor which is typically found on immune cells of the eye. It is being evaluated for Dry Eye Disease.

                            Brand Name : OK-101

                            Molecule Type : Peptide

                            Upfront Cash : Not Applicable

                            July 10, 2024

                            Lead Product(s) : OK-101

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            OKYO Pharma

                            United Kingdom arrow
                            Medlab Asia & Asia Health
                            Not Confirmed

                            OKYO Pharma

                            United Kingdom arrow
                            Medlab Asia & Asia Health
                            Not Confirmed
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                            Lead Product(s) : OK-101

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            OKYO Pharma Announces Data from OK-101 Phase 2 Dry Eye Disease Trial

                            Details : OK-101 is a lipid-conjugated chemerin peptide agonist of the ChemR23 G-protein coupled receptor. It is being evaluated in phase 2 clinical trials to treat Dry Eye Disease.

                            Brand Name : OK-101

                            Molecule Type : Peptide

                            Upfront Cash : Not Applicable

                            July 10, 2024

                            Lead Product(s) : OK-101

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            EyePoint Pharmaceuticals

                            U.S.A arrow
                            Medlab Asia & Asia Health
                            Not Confirmed

                            EyePoint Pharmaceuticals

                            U.S.A arrow
                            Medlab Asia & Asia Health
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Vorolanib

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            EyePoint Pharmaceuticals Reports Topline Data from Phase 2 PAVIA Trial Of DURAVYU™

                            Details : Duravyu delivers vorolanib, a selective TKI in a bioerodible insert using EyePoint’s Durasert E™ technology, under phase 2 development for treating non-proliferative diabetic retinopathy.

                            Brand Name : Duravyu

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            May 06, 2024

                            Lead Product(s) : Vorolanib

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            Qlaris Bio

                            U.S.A arrow
                            Medlab Asia & Asia Health
                            Not Confirmed

                            Qlaris Bio

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                            Medlab Asia & Asia Health
                            Not Confirmed
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                            Lead Product(s) : QLS-111

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase II

                            Sponsor : Canaan

                            Deal Size : $24.0 million

                            Deal Type : Series B Financing

                            DEALS_DEV arrow-down

                            Qlaris Bio Completes $24 Million Series B Financing Round To Advance Qls-111

                            Details : The proceeds will support clinical development of QLS-111, a first-in-class therapeutic that targets episcleral venous pressure to reduce intraocular pressure in glaucoma and ocular hypertension.

                            Brand Name : QLS-111

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            April 30, 2024

                            Lead Product(s) : QLS-111

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase II

                            Sponsor : Canaan

                            Deal Size : $24.0 million

                            Deal Type : Series B Financing

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