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    [{"orgOrder":0,"company":"Oranomed","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2023","type":"Not Applicable","leadProduct":"\u00b2\u00b9\u00b2Pb-DOTAM-GRPR1","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"Oranomed","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Oranomed \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Oranomed \/ Not Applicable"},{"orgOrder":0,"company":"Oranomed","sponsor":"RadioMedix","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Peptide","year":"2023","type":"Not Applicable","leadProduct":"Alphamedix","moa":"","graph1":"Oncology","graph2":"Phase II","graph3":"Oranomed","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injectable\/Injection","sponsorNew":"Oranomed \/ Oranomed","highestDevelopmentStatusID":"8","companyTruncated":"Oranomed \/ Oranomed"},{"orgOrder":0,"company":"Oranomed","sponsor":"Orbit Discovery","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"UNITED KINGDOM","productType":"Peptide","year":"2023","type":"Collaboration","leadProduct":"Undisclosed","moa":"","graph1":"Oncology","graph2":"Discovery","graph3":"Oranomed","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Oranomed \/ Oranomed","highestDevelopmentStatusID":"2","companyTruncated":"Oranomed \/ Oranomed"},{"orgOrder":0,"company":"Oranomed","sponsor":"RadioMedix","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Peptide","year":"2024","type":"Not Applicable","leadProduct":"212Pb-DOTAMTATE","moa":"","graph1":"Oncology","graph2":"Phase II","graph3":"Oranomed","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Oranomed \/ Oranomed","highestDevelopmentStatusID":"8","companyTruncated":"Oranomed \/ Oranomed"},{"orgOrder":0,"company":"Oranomed","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"NVL-655","moa":"","graph1":"Oncology","graph2":"Phase II","graph3":"Oranomed","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Oranomed \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Oranomed \/ Not Applicable"},{"orgOrder":0,"company":"Oranomed","sponsor":"Sanofi","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Peptide","year":"2024","type":"Licensing Agreement","leadProduct":"212Pb-DOTAMTATE","moa":"","graph1":"Technology","graph2":"Approved","graph3":"Oranomed","amount2":0.35999999999999999,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"Oranomed \/ Sanofi","highestDevelopmentStatusID":"12","companyTruncated":"Oranomed \/ Sanofi"},{"orgOrder":0,"company":"Oranomed","sponsor":"Sanofi","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2024","type":"Agreement","leadProduct":"212Pb-based Radioligand Therapy","moa":"","graph1":"Technology","graph2":"Approved","graph3":"Oranomed","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"Oranomed \/ Sanofi","highestDevelopmentStatusID":"12","companyTruncated":"Oranomed \/ Sanofi"}]

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                            01

                            Oranomed

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                            Lead Product(s) : 212Pb-based Radioligand Therapy

                            Therapeutic Area : Oncology

                            Study Phase : Discovery

                            Sponsor : Sanofi

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Sanofi and Orano Join Forces to Develop Next-Generation Radioligand Medicines

                            Details : The agreement aims to combine Sanofi and Orano's expertise against rare cancers and accelerate the development of next-generation radioligand medicines based on 212Pb alpha-emitting isotopes.

                            Brand Name : Undisclosed

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            October 17, 2024

                            Lead Product(s) : 212Pb-based Radioligand Therapy

                            Therapeutic Area : Oncology

                            Highest Development Status : Discovery

                            Sponsor : Sanofi

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            02

                            Oranomed

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                            Lead Product(s) : Alphamedix

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Sanofi

                            Deal Size : $357.1 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Sanofi, RadioMedix, Orano Med Announce Agreement on Radioligand Medicine for Cancers

                            Details : Sanofi will be responsible for the global commercialization of AlphaMedix, while Orano will manufacture AlphaMedix through its global industrial platform currently under development.

                            Brand Name : AlphaMedix

                            Molecule Type : Peptide

                            Upfront Cash : $111.6 million

                            September 12, 2024

                            Lead Product(s) : Alphamedix

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Sanofi

                            Deal Size : $357.1 million

                            Deal Type : Licensing Agreement

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                            03

                            Oranomed

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                            Lead Product(s) : Alphamedix

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Recipient : RadioMedix

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            RadioMedix and Orano Med Receive Breakthrough Designation for AlphaMedixTM

                            Details : AlphaMedix (212Pb-DOTAMTATE) is a targeted alpha therapy for unresectable, metastatic gastroenteropancreatic neuroendocrine tumors, naïve to peptide receptor therapy.

                            Brand Name : AlphaMedix

                            Molecule Type : Peptide

                            Upfront Cash : Not Applicable

                            February 12, 2024

                            Lead Product(s) : Alphamedix

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Recipient : RadioMedix

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Oranomed

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                            Lead Product(s) : NVL-655

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Nuvalent Initiates Phase 2 of ALKOVE-1 Trial for ALK-Positive NSCLC and Other Solid Tumors

                            Details : NVL-655 is a novel brain-penetrant ALK-selective tyrosine kinase inhibitor. It is being developed for the treatment of ALK-positive non-small cell lung cancer and other solid tumors.

                            Brand Name : NVL-655

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            February 12, 2024

                            Lead Product(s) : NVL-655

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Oranomed

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Discovery

                            Recipient : Orbit Discovery

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Orano Med and Orbit Discovery Enter Collaboration to Discover Novel Targeted Radioligand Therapies for Cancer

                            Details : Under the terms of the collaboration, Orbit will deploy its bead-based peptide display engine to discover peptide leads specific to targets related to specific tumours.

                            Brand Name : Undisclosed

                            Molecule Type : Peptide

                            Upfront Cash : Undisclosed

                            September 11, 2023

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Discovery

                            Recipient : Orbit Discovery

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            Lead Product(s) : Alphamedix

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Recipient : RadioMedix

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            RadioMedix and Orano Med Complete Patient Enrolment in Phase II Trial of Targeted Alpha-Emitter AlphaMedix in ...

                            Details : AlphaMedixTM is a radiolabeled SSTR-targeting therapeutic investigational drug for the treatment of NETs patients. The product consists of SSTR-targeting peptide complex radiolabeled with 212Pb dotamtate that serves as an in vivo generator of alpha-emitt...

                            Brand Name : AlphaMedix

                            Molecule Type : Peptide

                            Upfront Cash : Not Applicable

                            May 16, 2023

                            Lead Product(s) : Alphamedix

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Recipient : RadioMedix

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : ²¹²Pb-DOTAM-GRPR1

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Orano Med Starts Phase I Trial With Alpha Radioligand Therapy 212Pb-GRPR in Patients With Solid Tumors

                            Details : 212Pb-DOTAM-G is a 212Pb-conjugated anti-GRPR (Gastrin-Releasing Peptide Receptor) targeting different types of solid tumors including several breast and prostate cancers tumor types.

                            Brand Name : ²¹²Pb-DOTAM-GRPR1

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            January 04, 2023

                            Lead Product(s) : ²¹²Pb-DOTAM-GRPR1

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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