Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Sanofi and Orano Join Forces to Develop Next-Generation Radioligand Medicines
Details : The agreement aims to combine Sanofi and Orano's expertise against rare cancers and accelerate the development of next-generation radioligand medicines based on 212Pb alpha-emitting isotopes.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
October 17, 2024
Lead Product(s) : Alphamedix
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Sanofi
Deal Size : $357.1 million
Deal Type : Licensing Agreement
Sanofi, RadioMedix, Orano Med Announce Agreement on Radioligand Medicine for Cancers
Details : Sanofi will be responsible for the global commercialization of AlphaMedix, while Orano will manufacture AlphaMedix through its global industrial platform currently under development.
Brand Name : AlphaMedix
Molecule Type : Peptide
Upfront Cash : $111.6 million
September 12, 2024
Lead Product(s) : Alphamedix
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Sanofi
Deal Size : $357.1 million
Deal Type : Licensing Agreement
Lead Product(s) : Alphamedix
Therapeutic Area : Oncology
Study Phase : Phase II
Recipient : RadioMedix
Deal Size : Not Applicable
Deal Type : Not Applicable
RadioMedix and Orano Med Receive Breakthrough Designation for AlphaMedixTM
Details : AlphaMedix (212Pb-DOTAMTATE) is a targeted alpha therapy for unresectable, metastatic gastroenteropancreatic neuroendocrine tumors, naïve to peptide receptor therapy.
Brand Name : AlphaMedix
Molecule Type : Peptide
Upfront Cash : Not Applicable
February 12, 2024
Lead Product(s) : Alphamedix
Therapeutic Area : Oncology
Highest Development Status : Phase II
Recipient : RadioMedix
Deal Size : Not Applicable
Deal Type : Not Applicable
Nuvalent Initiates Phase 2 of ALKOVE-1 Trial for ALK-Positive NSCLC and Other Solid Tumors
Details : NVL-655 is a novel brain-penetrant ALK-selective tyrosine kinase inhibitor. It is being developed for the treatment of ALK-positive non-small cell lung cancer and other solid tumors.
Brand Name : NVL-655
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 12, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Discovery
Recipient : Orbit Discovery
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Under the terms of the collaboration, Orbit will deploy its bead-based peptide display engine to discover peptide leads specific to targets related to specific tumours.
Brand Name : Undisclosed
Molecule Type : Peptide
Upfront Cash : Undisclosed
September 11, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Discovery
Recipient : Orbit Discovery
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Alphamedix
Therapeutic Area : Oncology
Study Phase : Phase II
Recipient : RadioMedix
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : AlphaMedixTM is a radiolabeled SSTR-targeting therapeutic investigational drug for the treatment of NETs patients. The product consists of SSTR-targeting peptide complex radiolabeled with 212Pb dotamtate that serves as an in vivo generator of alpha-emitt...
Brand Name : AlphaMedix
Molecule Type : Peptide
Upfront Cash : Not Applicable
May 16, 2023
Lead Product(s) : Alphamedix
Therapeutic Area : Oncology
Highest Development Status : Phase II
Recipient : RadioMedix
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : 212Pb-DOTAM-G is a 212Pb-conjugated anti-GRPR (Gastrin-Releasing Peptide Receptor) targeting different types of solid tumors including several breast and prostate cancers tumor types.
Brand Name : ²¹²Pb-DOTAM-GRPR1
Molecule Type : Large molecule
Upfront Cash : Not Applicable
January 04, 2023
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