Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Orca Bio Completes Enrollment for Precision-T Phase 3 Study
Details : Orca-T is an investigational allogeneic T-cell immunotherapy being evaluated in clinical trials for the treatment of multiple hematologic malignancies, such as AML.
Brand Name : Orca-T
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
June 05, 2024
Details : Orca-Q is an investigational allogeneic cellular therapy consisting of a single infusion containing a proprietary composition of stem and immune cells derived from peripheral blood from either related or unrelated matched, unmatched or haploidentical don...
Brand Name : OrcaGraft
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
November 03, 2022
Details : TregGraft (Orca-T) is an investigational high-precision allogeneic cellular therapy consisting of infusions containing regulatory T-cells, conventional T-cells and CD34+ stem cells derived from peripheral blood from either related or unrelated matched do...
Brand Name : TregGraft
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
August 02, 2022
Orca Bio to Present New Clinical Data on Orca-T at the European Hematology Association 2022 Congress
Details : TregGraft (Orca-T) , an investigational, high-precision allogeneic cell therapy derived from stem and immune cells from either related or unrelated HLA-matched donors, is intended to safely replace a patient’s compromised blood and immune system with t...
Brand Name : TregGraft
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
May 12, 2022
Details : Pooled data from 137 patients show Orca-T, an investigational high-precision allogeneic cellular therapy improved overall survival and reduced chronic graft versus host disease compared to standard of care.
Brand Name : TregGraft
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
April 25, 2022
Lead Product(s) : TregGraft
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Early multi-center results indicate that Orca-T, a novel approach to HSCT, improves time-to-engraftment, markedly reduces the incidence and severity of GvHD, and significantly improved GRFS at 1 year.
Brand Name : Orca-T
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
December 06, 2020
Lead Product(s) : TregGraft
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : TregGraft
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Preliminary data from the Phase I/II clinical trials of Orca-T will be presented at the 62nd American Society of Hematology Annual Meeting. Data provide insights into manufacturing efficiency, logistics and early clinical outcomes of Orca-T for patients ...
Brand Name : Orca-T
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
November 04, 2020
Lead Product(s) : TregGraft
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : TregGraft
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Orca Bio Receives Regenerative Medicine Advanced Therapy (RMAT) Designation for Orca-T
Details : Orca-T is an allogeneic, high-precision cell therapy for patients with blood cancers who are eligible for a hematopoietic stem cell transplant. Orca-T has received ODD from the FDA for enhancing cell engraftment in patients who qualify for a hematopoieti...
Brand Name : Orca-T
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
October 14, 2020
Lead Product(s) : TregGraft
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : T cell therapies
Therapeutic Area : Oncology
Study Phase : Undisclosed
Sponsor : Lyell Immunopharma
Deal Size : Undisclosed
Deal Type : Partnership
Orca Bio and Lyell Immunopharma Announce Research Partnership
Details : The partnership promotes complementary scientific technologies to develop next generation cell-based therapies for patients with solid cancers.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
September 02, 2020
Lead Product(s) : T cell therapies
Therapeutic Area : Oncology
Highest Development Status : Undisclosed
Sponsor : Lyell Immunopharma
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : TRGFT-201
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Lightspeed Venture
Deal Size : $300.0 million
Deal Type : Series D Financing
Orca Bio Raises $192m to Support Cell Therapies Development
Details : The financing will support the continued advancement of Orca Bio’s cell therapy pipeline and its novel manufacturing platform, which sorts blood with single-cell precision and a high level of purity and speed to create optimal therapeutic mixtures of i...
Brand Name : TRGFT-201
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
June 17, 2020
Lead Product(s) : TRGFT-201
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Lightspeed Venture
Deal Size : $300.0 million
Deal Type : Series D Financing
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