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Find Clinical Drug Pipeline Developments & Deals by Orgenesis

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Lead Product(s) : Autologous mesenchymal stem cells infected oncolytic virus

                          Therapeutic Area : Oncology

                          Study Phase : Phase I

                          Recipient : Hospital Infantil Universitario Niño Jesús

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

                          Details : The POCare Platform has been designed by Orgenesis to enable hospitals and healthcare facilities globally to develop, optimize and manufacture cell and gene therapies throughout a POC Network of global healthcare facilities.

                          Brand Name : Celyvir

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          March 11, 2021

                          Lead Product(s) : Autologous mesenchymal stem cells infected oncolytic virus

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Recipient : Hospital Infantil Universitario Niño Jesús

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          02

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Following closing of the Transaction, Orgenesis plans to accelerate the commercial scaleup of KYSLECEL throughout the United States and, subject to regulatory and logistical considerations, in international markets as well.

                          Brand Name : Kyslecel

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          September 29, 2020

                          Lead Product(s) : Autologous pancreatic islets cells

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Approved

                          Recipient : Koligo Therapeutics

                          Deal Size : $16.3 million

                          Deal Type : Acquisition

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                          03

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : The agreement is part of the Orgenesis strategy of growing and expanding the POCare Network. The first collaboration under the agreement will focus on the clinical development of CAR-T and whole cell-based vaccine platform for use in cancer immunotherapi...

                          Brand Name : Undisclosed

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          July 14, 2020

                          Lead Product(s) : CAR-T cell therapy

                          Therapeutic Area : Oncology

                          Highest Development Status : Undisclosed

                          Recipient : Educell

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          04

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Orgenesis has entered into a preliminary, non-binding term sheet with Leidos to develop and potentially obtain FDA marketing approval of Orgenesis’ Ranpirnase for the systemic treatment of patients suffering with SARS-CoV-2 the virus that causes COVID-...

                          Brand Name : Undisclosed

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          June 24, 2020

                          Lead Product(s) : Ranpirnase

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Sponsor : Leidos

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          05

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Clinical study will be undertaken with goal of utilizing and validating a number of Orgenesis’ proprietary POCare Technologies, including an automated cell culturing system for the generation and expansion tumor infiltrating lymphocytes for use in adop...

                          Brand Name : Undisclosed

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          June 01, 2020

                          Lead Product(s) : Tumor infiltrating lymphocytes

                          Therapeutic Area : Oncology

                          Highest Development Status : Undisclosed

                          Recipient : Edith Wolfson Medical Center

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          06

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Orgenesis and TamirBio plan to combine ranpirnase with Bioxomes, which have shown the ability to fuse with cell membranes and deliver an intracellular cargo, in a similar manner to natural exosomes.

                          Brand Name : Undisclosed

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          April 14, 2020

                          Lead Product(s) : Ranpirnase

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I/ Phase II

                          Recipient : Tamir Biotechnology

                          Deal Size : $19.0 million

                          Deal Type : Acquisition

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