Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Undisclosed
Therapeutic Area : Hematology
Study Phase : Discovery
Sponsor : Vertex Pharmaceuticals
Deal Size : $700.0 million
Deal Type : Collaboration
Orna, Vertex Partner on SCD, Beta Thalassemia Gene Therapy Development
Details : Through the collaboration, Vertex will utilize Orna's proprietary LNP delivery solutions to enhance it's efforts in developing next-gen gene editing therapies for patients with SCD and TDT.
Product Name : Undisclosed
Product Type : Cell and Gene therapy
Upfront Cash : $65.0 million
January 07, 2025
Lead Product(s) : Undisclosed
Therapeutic Area : Hematology
Highest Development Status : Discovery
Sponsor : Vertex Pharmaceuticals
Deal Size : $700.0 million
Deal Type : Collaboration
Lead Product(s) : Circular RNA-based Vaccine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Discovery Platform
Sponsor : Merck & Co
Deal Size : $3,650.0 million
Deal Type : Collaboration
Merck and Orna Therapeutics Collaborate to Advance Orna’s Next Generation of RNA Technology
Details : Under the agreement, Merck will discover, develop, and commercialize multiple programs, including vaccines and therapeutics in the areas of infectious disease and oncology by using Orna’s proprietary oRNA technology.
Product Name : Undisclosed
Product Type : Vaccine
Upfront Cash : $150.0 million
August 16, 2022
Lead Product(s) : Circular RNA-based Vaccine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Discovery Platform
Sponsor : Merck & Co
Deal Size : $3,650.0 million
Deal Type : Collaboration
Lead Product(s) : ORN-101
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : First in vivo studies for ORN-101, demonstrated the potential of Orna's circular RNA (oRNA™) platform in cancer, genetic disorders, and infectious diseases.
Product Name : ORN-101
Product Type : Cell and Gene therapy
Upfront Cash : Not Applicable
May 02, 2022
Lead Product(s) : ORN-101
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable