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    [{"orgOrder":0,"company":"Orum Therapeutics","sponsor":"IMM Investment","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2021","type":"Series B Financing","leadProduct":"ORM-5029","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"Orum Therapeutics","amount2":0.080000000000000002,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0.080000000000000002,"dosageForm":"","sponsorNew":"Orum Therapeutics \/ IMM Investment","highestDevelopmentStatusID":"6","companyTruncated":"Orum Therapeutics \/ IMM Investment"},{"orgOrder":0,"company":"Orum Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2022","type":"Not Applicable","leadProduct":"ORM-5029","moa":"","graph1":"Oncology","graph2":"IND Enabling","graph3":"Orum Therapeutics","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Orum Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"5","companyTruncated":"Orum Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Orum Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2022","type":"Not Applicable","leadProduct":"ORM-5029","moa":"","graph1":"Oncology","graph2":"IND Enabling","graph3":"Orum Therapeutics","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Orum Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"5","companyTruncated":"Orum Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Orum Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2022","type":"Not Applicable","leadProduct":"ORM-5029","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"Orum Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Orum Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Orum Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Orum Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2022","type":"Not Applicable","leadProduct":"ORM-6151","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"Orum Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Orum Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Orum Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Orum Therapeutics","sponsor":"Bristol Myers Squibb","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2023","type":"Acquisition","leadProduct":"ORM-6151","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"Orum Therapeutics","amount2":0.28000000000000003,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0.28000000000000003,"dosageForm":"","sponsorNew":"Orum Therapeutics \/ Bristol Myers Squibb","highestDevelopmentStatusID":"6","companyTruncated":"Orum Therapeutics \/ Bristol Myers Squibb"}]

    Find Clinical Drug Pipeline Developments & Deals by Orum Therapeutics

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                            01

                            Orum Therapeutics

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                            Lead Product(s) : ORM-6151

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Bristol Myers Squibb

                            Deal Size : $280.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Orum Therapeutics Announces Acquisition of ORM-6151 Program by Bristol Myers Squibb

                            Details : BMS has acquired Orum’s ORM-6151, a first-in-class, anti-CD33 antibody-enabled GSPT1 degrader that has received the FDA’s clearance for Phase 1 for the treatment of patients with acute myeloid leukemia or high-risk myelodysplastic syndromes.

                            Brand Name : ORM-6151

                            Molecule Type : Large molecule

                            Upfront Cash : $100.0 million

                            November 06, 2023

                            Lead Product(s) : ORM-6151

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Bristol Myers Squibb

                            Deal Size : $280.0 million

                            Deal Type : Acquisition

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                            02

                            Orum Therapeutics

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                            Lead Product(s) : ORM-6151

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Orum Therapeutics Presents Positive Preclinical Data of ORM-6151, a First-in-Class, CD33-GSPT1 Dual-Precision ...

                            Details : ORM-6151 is the second drug candidate from Orum’s Dual-Precision Targeted Protein Degradation (TPD2 TM) approach, which combines the catalytic mechanism of TPDs with the precision of tumor-targeting therapeutic antibodies.

                            Brand Name : ORM-6151

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            December 10, 2022

                            Lead Product(s) : ORM-6151

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

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                            Lead Product(s) : ORM-5029

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Orum Therapeutics Announces First Patient Dosed in Phase 1 Clinical Trial of ORM-5029 in Development to Treat ...

                            Details : ORM-5029 is a first-in-class drug candidate designed to selectively deliver catalytic GSPT1 protein degraders to HER2-expressing tumor cells via antibody targeting. The study is designed to evaluate the safety, pharmacokinetics, and preliminary anti-tumo...

                            Brand Name : ORM-5029

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            October 31, 2022

                            Lead Product(s) : ORM-5029

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : ORM-5029

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Orum Therapeutics Presents Preclinical Data at AACR 2022 Highlighting Novel Dual-Precision Targeted Protein De...

                            Details : ORM-5029, a potential first-in-class TPD therapy for HER2-positive cancer, displays robust efficacy both in vitro and in vivo compared to other small molecule GSPT1 degraders and approved antibody drug conjugates (ADCs).

                            Brand Name : ORM-5029

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            April 08, 2022

                            Lead Product(s) : ORM-5029

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : ORM-5029

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Orum Therapeutics to Present Preclinical Data for ORM-5029, a Novel Antibody Neodegrader Conjugate, at the AAC...

                            Details : ORM-5029, a potential first-in-class targeted protein degrader therapy is built on novel targeted protein degrader combined with the precise tumor cell delivery mechanisms of antibodies for HER2-expressing breast cancer.

                            Brand Name : ORM-5029

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            March 08, 2022

                            Lead Product(s) : ORM-5029

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : ORM-5029

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : IMM Investment

                            Deal Size : $84.0 million

                            Deal Type : Series B Financing

                            DEALS_DEV arrow-down

                            Orum Therapeutics Closes $84 Million Series B Financing to Advance Novel Targeted Protein Degrader Payloads in...

                            Details : The lead therapeutic programs from Orum’s AnDC platform are ORM-5029 for the treatment of solid tumors and ORM-6151 for the treatment of hematological cancers.

                            Brand Name : ORM-5029

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            June 24, 2021

                            Lead Product(s) : ORM-5029

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : IMM Investment

                            Deal Size : $84.0 million

                            Deal Type : Series B Financing

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