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                          Top Deals by Deal Size (USD bn)

                          01

                          BioFlorida Conference
                          Not Confirmed
                          BioFlorida Conference
                          Not Confirmed

                          Details : The financing will advance the development of Osteal’s portfolio of therapies, including the submission of NDA and accelerated commercial launch of VT-X7 for treating PJI of the hip and knee.

                          Brand Name : VT-X7

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          June 05, 2024

                          Lead Product(s) : Vancomycin Hydrochloride,Tobramycin Sulfate

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Johnson & Johnson

                          Deal Size : Undisclosed

                          Deal Type : Series D Financing

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                          02

                          BioFlorida Conference
                          Not Confirmed
                          BioFlorida Conference
                          Not Confirmed

                          Details : VT-X7 (vancomycin hydrochloride and tobramycin sulfate) for irrigation is a novel drug/device combination product which is delivers broad-spectrum antibiotics, directly to the joint space and surrounding tissue to treat periprosthetic joint infection (PJ...

                          Brand Name : VT-X7

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          December 05, 2023

                          Lead Product(s) : Vancomycin Hydrochloride,Tobramycin Sulfate

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          BioFlorida Conference
                          Not Confirmed
                          BioFlorida Conference
                          Not Confirmed

                          Details : The proceeds will support NDA submission and preparation for commercial launch of company's VT-X7, a novel drug/device combination product designed to deliver therapeutic concentrations of vancomycin hydrochloride and tobramycin, for periprosthetic joint...

                          Brand Name : VT-X7

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          September 21, 2023

                          Lead Product(s) : Vancomycin Hydrochloride,Tobramycin Sulfate

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Asteroid Partners

                          Deal Size : $23.0 million

                          Deal Type : Series C Financing

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                          04

                          BioFlorida Conference
                          Not Confirmed
                          BioFlorida Conference
                          Not Confirmed

                          Details : VT-X7 (vancomycin hydrochloride and tobramycin sulfate) for irrigation is a novel drug/device combination product which is delivers broad-spectrum antibiotics, directly to the joint space and surrounding tissue to treat periprosthetic joint infection (PJ...

                          Brand Name : VT-X7

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          February 07, 2023

                          Lead Product(s) : Vancomycin Hydrochloride,Tobramycin Sulfate

                          Therapeutic Area : Musculoskeletal

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          BioFlorida Conference
                          Not Confirmed
                          BioFlorida Conference
                          Not Confirmed

                          Details : VT-X7, (Vancomycin Hydrochloride), a drug/device combination product that locally delivers, via irrigation, highly targeted antibiotic therapy to the hip or knee during an accelerated seven-day interstage period of a two-stage exchange arthroplasty.

                          Brand Name : VT-X7

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          November 04, 2022

                          Lead Product(s) : Vancomycin Hydrochloride,Tobramycin

                          Therapeutic Area : Musculoskeletal

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          BioFlorida Conference
                          Not Confirmed
                          BioFlorida Conference
                          Not Confirmed

                          Details : The proceeds will enable Osteal to continue development of its integrated technologies, advance the clinical development of its lead candidate, VT-X7 for treatment of periprosthetic joint infection and fund new research programs.

                          Brand Name : VT-X7

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          March 08, 2022

                          Lead Product(s) : Vancomycin Hydrochloride,Tobramycin

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : HM Capital

                          Deal Size : $30.0 million

                          Deal Type : Series B Financing

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