Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Oteseconazole
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved
Sponsor : Mycovia Pharmaceuticals
Deal Size : Not Applicable
Deal Type : Not Applicable
Mycovia Announces VIVJOA® Launch for Severe Vulvovaginal Candidiasis in China
Details : Vivjoa (oteseconazole) is a selective and orally bioavailable CYP51 inhibitor antifungal, which is approved in China for the treatment of severe vulvovaginal candidiasis.
Brand Name : Vivjoa
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 07, 2024
Lead Product(s) : Oteseconazole
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved
Sponsor : Mycovia Pharmaceuticals
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Oteseconazole
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved
Sponsor : Jiangsu Hengrui Medicine
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : VIVJOA® (oteseconazole) is an azole antifungal and designed to selectively inhibit fungal CYP51, which is indicated for the treatment of severe vulvovaginal candidiasis (VVC).
Brand Name : Vivjoa
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 21, 2023
Lead Product(s) : Oteseconazole
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved
Sponsor : Jiangsu Hengrui Medicine
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Oteseconazole
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : VIVJOA (oteseconazole) was statistically superior to placebo in preventing recurrence of infection in women with RVVC and noninferior to fluconazole in treating acute VVC in women with RVVC.
Brand Name : Vivjoa
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 25, 2022
Lead Product(s) : Oteseconazole
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Oteseconazole
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Of the 71 VIVJOA (oteseconazole) treated participants in the observational extension study, 85% completed 96 weeks without a recurrent VVC episode, where they had experienced at least three episodes in the year prior to study entry.
Brand Name : Vivjoa
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 02, 2022
Lead Product(s) : Oteseconazole
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Oteseconazole
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Two global VIOLET Phase 3 studies met primary and key secondary endpoints, with authors concluding VIVJOA (oteseconazole) is highly efficacious in preventing recurrence of VVC through 48 weeks in participants with a history of RVVC.
Brand Name : Vivjoa
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 26, 2022
Lead Product(s) : Oteseconazole
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Oteseconazole
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : VIVJOA™ (oteseconazole) capsules are an azole antifungal indicated to reduce the incidence of recurrent vulvovaginal candidiasis (RVVC) in females with a history of RVVC who are NOT of reproductive potential.
Brand Name : Vivjoa
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 18, 2022
Lead Product(s) : Oteseconazole
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Oteseconazole
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : 85% of patients who took a 12-week course of Vivjoa (oteseconazole) completed 96 weeks without a recurrent VVC episode, with an average time of 92 weeks without recurrence.
Brand Name : Vivjoa
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 22, 2022
Lead Product(s) : Oteseconazole
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Oteseconazole
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Approval of VIVJOA™ marks a significant therapeutic advancement for reducing the incidence of RVVC, a condition with substantial unmet need, in permanently infertile and postmenopausal women.
Brand Name : Vivjoa
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 28, 2022
Lead Product(s) : Oteseconazole
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Oteseconazole
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Oteseconazole (VT-1161) is a novel, oral therapy for RVVC that is designed with the goal of having greater selectivity, fewer side effects and improved efficacy for treatment of recurrent vulvovaginal candidiasis (RVVC).
Brand Name : VT-1161
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 29, 2021
Lead Product(s) : Oteseconazole
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Oteseconazole
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Oteseconazole’s clinical development plan was comprised of three trials – two global VIOLET studies and one U.S.-focused ultraVIOLET study, including more than 870 patients at 232 sites across 11 countries.
Brand Name : VT-1161
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 01, 2021
Lead Product(s) : Oteseconazole
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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