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Find Clinical Drug Pipeline Developments & Deals for Oteseconazole

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                          Top Deals by Deal Size (USD bn)

                          01

                          Jiangsu Hengrui Pharmaceuticals

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                          Antibody Engineering
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                          Jiangsu Hengrui Pharmaceuticals

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                          Antibody Engineering
                          Not Confirmed

                          Details : Vivjoa (oteseconazole) is a selective and orally bioavailable CYP51 inhibitor antifungal, which is approved in China for the treatment of severe vulvovaginal candidiasis.

                          Brand Name : Vivjoa

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          February 07, 2024

                          Lead Product(s) : Oteseconazole

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Mycovia Pharmaceuticals

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : VIVJOA® (oteseconazole) is an azole antifungal and designed to selectively inhibit fungal CYP51, which is indicated for the treatment of severe vulvovaginal candidiasis (VVC).

                          Brand Name : Vivjoa

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          August 21, 2023

                          Lead Product(s) : Oteseconazole

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Jiangsu Hengrui Medicine

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : VIVJOA (oteseconazole) was statistically superior to placebo in preventing recurrence of infection in women with RVVC and noninferior to fluconazole in treating acute VVC in women with RVVC.

                          Brand Name : Vivjoa

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          August 25, 2022

                          Lead Product(s) : Oteseconazole

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Of the 71 VIVJOA (oteseconazole) treated participants in the observational extension study, 85% completed 96 weeks without a recurrent VVC episode, where they had experienced at least three episodes in the year prior to study entry.

                          Brand Name : Vivjoa

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          August 02, 2022

                          Lead Product(s) : Oteseconazole

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Two global VIOLET Phase 3 studies met primary and key secondary endpoints, with authors concluding VIVJOA (oteseconazole) is highly efficacious in preventing recurrence of VVC through 48 weeks in participants with a history of RVVC.

                          Brand Name : Vivjoa

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          July 26, 2022

                          Lead Product(s) : Oteseconazole

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : VIVJOA™ (oteseconazole) capsules are an azole antifungal indicated to reduce the incidence of recurrent vulvovaginal candidiasis (RVVC) in females with a history of RVVC who are NOT of reproductive potential.

                          Brand Name : Vivjoa

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          July 18, 2022

                          Lead Product(s) : Oteseconazole

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : 85% of patients who took a 12-week course of Vivjoa (oteseconazole) completed 96 weeks without a recurrent VVC episode, with an average time of 92 weeks without recurrence.

                          Brand Name : Vivjoa

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          June 22, 2022

                          Lead Product(s) : Oteseconazole

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Approval of VIVJOA™ marks a significant therapeutic advancement for reducing the incidence of RVVC, a condition with substantial unmet need, in permanently infertile and postmenopausal women.

                          Brand Name : Vivjoa

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          April 28, 2022

                          Lead Product(s) : Oteseconazole

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Oteseconazole (VT-1161) is a novel, oral therapy for RVVC that is designed with the goal of having greater selectivity, fewer side effects and improved efficacy for treatment of recurrent vulvovaginal candidiasis (RVVC).

                          Brand Name : VT-1161

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 29, 2021

                          Lead Product(s) : Oteseconazole

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Oteseconazole’s clinical development plan was comprised of three trials – two global VIOLET studies and one U.S.-focused ultraVIOLET study, including more than 870 patients at 232 sites across 11 countries.

                          Brand Name : VT-1161

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          June 01, 2021

                          Lead Product(s) : Oteseconazole

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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