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                          Therapeutic Area by Lead Product

                          Study Phase by Lead Product

                          Company by Lead Product

                          Top Deals by Deal Size (USD bn)

                          01

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : VIS649 (sibeprenlimab) is an investigational monoclonal antibody that blocks the action of APRIL (A PRoliferation-Inducing Ligand) for the treatment of immunoglobulin a nephropathy in adults.

                          Brand Name : VIS649

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          October 22, 2024

                          Lead Product(s) : Sibeprenlimab

                          Therapeutic Area : Nephrology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Through the acquisition, Otsuka will leverage Jana pipelines, which include JNT-517 an allosteric small molecule inhibitor of SLC6A19. It is being evaluated for the treatment of phenylketonuria.

                          Brand Name : JNT-517

                          Molecule Type : Small molecule

                          Upfront Cash : $800.0 million

                          August 01, 2024

                          Lead Product(s) : JNT-517

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Recipient : Jnana Therapeutics

                          Deal Size : $1,125.0 million

                          Deal Type : Acquisition

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                          03

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Rexulti (brexpiprazole) is an partial agonist of serotonin 5-HT1A, which is being investigated in combination therapy with sertraline for the treatment of post-traumatic stress disorder (PTSD).

                          Brand Name : Rexulti

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          June 25, 2024

                          Lead Product(s) : Brexpiprazole,Sertraline Hydrochloride

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase III

                          Sponsor : H. Lundbeck AS

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Ionis entered into a license agreement with Otsuka & obtained exclusive rights across the Asia-Pacific region for IONIS-PKK-LRx (donidalorsen) for treating hereditary angioedema.

                          Brand Name : IONIS-PKK-LRx

                          Molecule Type : Large molecule

                          Upfront Cash : $20.0 million

                          June 18, 2024

                          Lead Product(s) : Donidalorsen

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Recipient : Ionis Pharmaceuticals

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          05

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Rexulti (brexpiprazole) is an partial agonist activity at serotonin 5-HT1A, which is being investigated in combination therapy with sertraline for the treatment of post-traumatic stress disorder.

                          Brand Name : Rexulti

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          April 09, 2024

                          Lead Product(s) : Brexpiprazole,Sertraline Hydrochloride

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase III

                          Sponsor : H. Lundbeck AS

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Rexulti (brexpiprazole) 5-HT2A receptor, is being evaluated in combination with sertraline in late-stage clinical trials with adult patients for the treatment of post-traumatic stress disorder.

                          Brand Name : Rexulti

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          April 09, 2024

                          Lead Product(s) : Brexpiprazole,Sertraline Hydrochloride

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase III

                          Sponsor : H. Lundbeck AS

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Abilify Maintena (aripiprazole) is an atypical antipsychotic approved for maintaining treatment of schizophrenia in adults stabilized with aripiprazole.

                          Brand Name : Abilify Maintena

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          March 27, 2024

                          Lead Product(s) : Aripiprazole

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Entresto (sacubitril and valsartan) is an oral angiotensin receptor neprilysin inhibitor, which is approved for the treatment of additional indication of pediatric chronic heart failure.

                          Brand Name : Entresto

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          March 26, 2024

                          Lead Product(s) : Sacubitril Sodium,Valsartan

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Approved

                          Recipient : Novartis Pharmaceuticals Corporation

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : OPC-167832 (quabodepistat) is a potent and orally active dprE1 inhibitor, which is being evaluated in combination with delamanid & bedaquiline for the treatment of pulmonary tuberculosis.

                          Brand Name : OPC-167832

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          March 22, 2024

                          Lead Product(s) : OPC-167832,Delamanid,Bedaquiline

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Under the license agreement, Otsuka holds exclusive rights to develop, manufacture, and commercialize SEP-363856 (ulotaront), TAAR1 agonist. It is being evaluated with the patient for Schizophrenia.

                          Brand Name : SEP-363856

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          March 15, 2024

                          Lead Product(s) : Ulotaront

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase III

                          Recipient : Sumitomo Pharma

                          Deal Size : $30.0 million

                          Deal Type : Licensing Agreement

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