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Find Clinical Drug Pipeline Developments & Deals for OTT166

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                          Top Deals by Deal Size (USD bn)

                          01

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : OTT166 is an investigational, novel, potent and selective small molecule RGD integrin inhibitor to allow it to distribute to the retina in high concentrations after topical (eye drop) administration to the eye.

                          Brand Name : OTT166

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          July 18, 2023

                          Lead Product(s) : OTT166

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : OTT166,an investigational, novel, patented, potent and selective small molecule RGD integrin inhibitor demonstrated ability to reach retina from eye drop application and produced robust biological activity signal in patients.

                          Brand Name : OTT166

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 19, 2022

                          Lead Product(s) : OTT166

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : OTT166 has demonstrated tolerability and promising evidence of biological activity in patients in Phase 1b and has potential to dramatically change treatment paradigm by enabling earlier, non-invasive, active treatment for patients with diabetic retinopa...

                          Brand Name : OTT166

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          August 02, 2022

                          Lead Product(s) : OTT166

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : Proceeds will support the DR-EAM (Diabetic Retinopathy - Early Active Management) Phase 2 study of OTT166 in patients with moderate to severe non-proliferative and mild proliferative diabetic retinopathy. The study is expected to commence early next year...

                          Brand Name : OTT166

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          November 09, 2021

                          Lead Product(s) : OTT166

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase I

                          Sponsor : Undisclosed

                          Deal Size : $35.0 million

                          Deal Type : Series B Financing

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