Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Loncastuximab Tesirine
Therapeutic Area : Oncology
Study Phase : Approved FDF
Recipient : ADC Therapeutics
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Zynlonta (loncastuximab tesirine-lpyl), an antibody-drug conjugate (ADC) targeting CD19, is approved by FDA and EU for the treatment of adult patients with relapsed or refractory (r/r) diffuse large B-cell lymphoma (DLBCL).
Product Name : Zynlonta
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
July 24, 2023
Lead Product(s) : Loncastuximab Tesirine
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Recipient : ADC Therapeutics
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Loncastuximab Tesirine,Rituximab
Therapeutic Area : Oncology
Study Phase : Phase III
Recipient : ADC Therapeutics
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ZYNLONTA® (loncastuximab tesirine-lpyl) is a CD19-directed antibody drug conjugate (ADC). Once bound to a CD19-expressing cell, ZYNLONTA is internalized by the cell, where enzymes release a pyrrolobenzodiazepine (PBD) payload.
Product Name : Zynlonta
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
July 11, 2022
Lead Product(s) : Loncastuximab Tesirine,Rituximab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Recipient : ADC Therapeutics
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Loncastuximab Tesirine,Rituximab
Therapeutic Area : Oncology
Study Phase : Phase III
Recipient : Overland ADCT BioPharma
Deal Size : $50.0 million
Deal Type : Agreement
ADC Therapeutics and Overland Pharmaceuticals Announce Formation of Overland ADCT BioPharma
Details : ADC Therapeutics licensed exclusive development and commercialization rights to Lonca, ADCT-602, ADCT-601 and ADCT-901 for greater China and Singapore to Overland ADCT BioPharma. Overland Pharmaceuticals will have a 51% stake and ADC Therapeutics, 49%.
Product Name : Lonca
Product Type : Antibody-drug Conjugate
Upfront Cash : Undisclosed
December 14, 2020
Lead Product(s) : Loncastuximab Tesirine,Rituximab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Recipient : Overland ADCT BioPharma
Deal Size : $50.0 million
Deal Type : Agreement