Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : KYV-101
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Kyverna Therapeutics
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Under the agreement, Kyverna gains access to LentiVector® platform, the first commercially approved lentiviral-based gene delivery system, to use with any Kyverna product, including its anti-CD19 CAR T-cell therapies, KYV-101 and KYV-201 which specifica...
Brand Name : KYV-101
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
September 20, 2023
Lead Product(s) : KYV-101
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Kyverna Therapeutics
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Study Phase : Undisclosed
Sponsor : Undisclosed
Deal Size : Undisclosed
Deal Type : Partnership
Oxford Biomedica Solutions Forms New Partnerships With Three Biotechnology Companies
Details : Oxford Biomedica Solutions will provide its full platform offering to support the new partners’ pre-clinical gene therapy programmes, which cover development programmes including CNS, autoimmune disease, oncology, muscular disorder, and rare metabolic ...
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
December 14, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Highest Development Status : Undisclosed
Sponsor : Undisclosed
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : CAR-T Therapy
Therapeutic Area : Technology
Study Phase : Undisclosed
Sponsor : LSA
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : The LSA grants the new partner a non-exclusive licence to utilise Oxford Biomedica’s LentiVector® platform for its application in their lead CAR-T programme, and puts in place a three-year Clinical Supply Agreement.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
July 26, 2022
Lead Product(s) : CAR-T Therapy
Therapeutic Area : Technology
Highest Development Status : Undisclosed
Sponsor : LSA
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : OTL-203
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : Orchard Therapeutics
Deal Size : Not Applicable
Deal Type : Not Applicable
Oxford Biomedica Initiates New Project With Orchard Therapeutics Utilising LentiStable™ Technology
Details : OTL-203, an investigational hemopoietic stem cell (HSC) gene therapy in development for the potential treatment of mucopolysaccharidosis type I Hurler’s syndrome (MPS-IH).
Brand Name : OTL-203
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
July 26, 2022
Lead Product(s) : OTL-203
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : Orchard Therapeutics
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Recombinant ChAdOx1-S
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved
Sponsor : AstraZeneca
Deal Size : Undisclosed
Deal Type : Agreement
Oxford Biomedica Signs New Three Year Agreement with AstraZeneca
Details : The manufacture of COVID-19 vaccines, Vaxzevria (Recombinant ChAdOx1-S), at Oxford Biomedica’s Oxbox facility is expected to complete in the last quarter of 2022, will be available to AstraZeneca on an as needed basis beyond 2022.
Brand Name : Vaxzevria
Molecule Type : Vaccine
Upfront Cash : Undisclosed
July 01, 2022
Lead Product(s) : Recombinant ChAdOx1-S
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved
Sponsor : AstraZeneca
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : AXO-Lenti-PD
Therapeutic Area : Neurology
Study Phase : Phase I/ Phase II
Sponsor : Sio Gene Therapies
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Sio intends to return the global rights for AXO-Lenti-PD and that they intend to cease work on this gene therapy programme in Parkinson’s Disease. Sio is currently conducting a Phase 2 SUNRISE-PD trial with AXO-Lenti-PD.
Brand Name : OXB-102
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
January 31, 2022
Lead Product(s) : AXO-Lenti-PD
Therapeutic Area : Neurology
Highest Development Status : Phase I/ Phase II
Sponsor : Sio Gene Therapies
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Tisagenlecleucel
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Oxford Biomedica In License and Supply Deals With Novartis and Arcellx
Details : Under the terms of the agreement, Oxford Biomedica will receive payments related to the development and manufacturing of lentiviral vectors for use in clinical trials with also allowing for payments for the manufacture and supply of lentiviral vectors fo...
Brand Name : Kymriah
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
December 13, 2021
Lead Product(s) : Tisagenlecleucel
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : ChAdOx1 nCoV-19
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved
Sponsor : AstraZeneca
Deal Size : Undisclosed
Deal Type : Agreement
Details : Oxford Biomedica announced an 18 month supply agreement in September 2020 under a three year Master Supply and Development Agreement with AstraZeneca for large-scale manufacture of the adenovirus vector-based COVID-19 vaccine, AZD1222.
Brand Name : AZD1222
Molecule Type : Vaccine
Upfront Cash : Undisclosed
May 18, 2021
Lead Product(s) : ChAdOx1 nCoV-19
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved
Sponsor : AstraZeneca
Deal Size : Undisclosed
Deal Type : Agreement
PhoreMost, Oxford Biomedica Enter Discovery Collaboration for Next-Gen CAR-T Therapies
Details : PhoreMost will deploy its in-house expertise and next-generation phenotypic screening platform, SITESEEKER®, to identify therapeutic candidates for Oxford Biomedica’s LentiVector® gene therapy delivery system.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
November 09, 2020
Lead Product(s) : AXO-Lenti-PD
Therapeutic Area : Neurology
Study Phase : Phase II
Recipient : Sio Gene Therapies
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : AXO-Lenti-PD gene therapy demonstrate consistent treatment outcomes including Favorable safety and tolerability profile, with no serious adverse events attributable to gene therapy; Improvement in Hauser diary “Good ON time” and “OFF time” and ot...
Brand Name : OXB-102
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
October 29, 2020
Lead Product(s) : AXO-Lenti-PD
Therapeutic Area : Neurology
Highest Development Status : Phase II
Recipient : Sio Gene Therapies
Deal Size : Not Applicable
Deal Type : Not Applicable
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