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    [{"orgOrder":0,"company":"Oxford Biomedica","sponsor":"AstraZeneca","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Vaccine","year":"2020","type":"Agreement","leadProduct":"AZD1222","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Phase II\/ Phase III","graph3":"Oxford Biomedica","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Intramuscular Injection","sponsorNew":"Oxford Biomedica \/ Astrazeneca","highestDevelopmentStatusID":"9","companyTruncated":"Oxford Biomedica \/ Astrazeneca"},{"orgOrder":0,"company":"Oxford Biomedica","sponsor":"Vaccines Manufacturing and Innovation Centre","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Vaccine","year":"2020","type":"Collaboration","leadProduct":"AZD1222","moa":"","graph1":"Infections and Infectious 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    Find Clinical Drug Pipeline Developments & Deals by Oxford Biomedica

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                            01

                            Oxford Biomedica

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                            Lead Product(s) : KYV-101

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Kyverna Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Kyverna Therapeutics and Oxford Biomedica Sign License and Supply Agreement for LentiVector® Platform

                            Details : Under the agreement, Kyverna gains access to LentiVector® platform, the first commercially approved lentiviral-based gene delivery system, to use with any Kyverna product, including its anti-CD19 CAR T-cell therapies, KYV-101 and KYV-201 which specifica...

                            Brand Name : KYV-101

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            September 20, 2023

                            Lead Product(s) : KYV-101

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Kyverna Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            02

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Study Phase : Undisclosed

                            Sponsor : Undisclosed

                            Deal Size : Undisclosed

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            Oxford Biomedica Solutions Forms New Partnerships With Three Biotechnology Companies

                            Details : Oxford Biomedica Solutions will provide its full platform offering to support the new partners’ pre-clinical gene therapy programmes, which cover development programmes including CNS, autoimmune disease, oncology, muscular disorder, and rare metabolic ...

                            Brand Name : Undisclosed

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            December 14, 2022

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Highest Development Status : Undisclosed

                            Sponsor : Undisclosed

                            Deal Size : Undisclosed

                            Deal Type : Partnership

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                            Lead Product(s) : CAR-T Therapy

                            Therapeutic Area : Technology

                            Study Phase : Undisclosed

                            Sponsor : LSA

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Oxford Biomedica Signs Licence & Supply Agreement with New Partner for LentiVector® Platform for CAR-T Therap...

                            Details : The LSA grants the new partner a non-exclusive licence to utilise Oxford Biomedica’s LentiVector® platform for its application in their lead CAR-T programme, and puts in place a three-year Clinical Supply Agreement.

                            Brand Name : Undisclosed

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            July 26, 2022

                            Lead Product(s) : CAR-T Therapy

                            Therapeutic Area : Technology

                            Highest Development Status : Undisclosed

                            Sponsor : LSA

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            Lead Product(s) : OTL-203

                            Therapeutic Area : Genetic Disease

                            Study Phase : Preclinical

                            Sponsor : Orchard Therapeutics

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Oxford Biomedica Initiates New Project With Orchard Therapeutics Utilising LentiStable™ Technology

                            Details : OTL-203, an investigational hemopoietic stem cell (HSC) gene therapy in development for the potential treatment of mucopolysaccharidosis type I Hurler’s syndrome (MPS-IH).

                            Brand Name : OTL-203

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            July 26, 2022

                            Lead Product(s) : OTL-203

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Preclinical

                            Sponsor : Orchard Therapeutics

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

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                            Lead Product(s) : Recombinant ChAdOx1-S

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved

                            Sponsor : AstraZeneca

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Oxford Biomedica Signs New Three Year Agreement with AstraZeneca

                            Details : The manufacture of COVID-19 vaccines, Vaxzevria (Recombinant ChAdOx1-S), at Oxford Biomedica’s Oxbox facility is expected to complete in the last quarter of 2022, will be available to AstraZeneca on an as needed basis beyond 2022.

                            Brand Name : Vaxzevria

                            Molecule Type : Vaccine

                            Upfront Cash : Undisclosed

                            July 01, 2022

                            Lead Product(s) : Recombinant ChAdOx1-S

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved

                            Sponsor : AstraZeneca

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            Lead Product(s) : AXO-Lenti-PD

                            Therapeutic Area : Neurology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Sio Gene Therapies

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Oxford Biomedica Announces that Sio Gene Therapies Intends to Cease the License Agreement for Gene Therapy Pro...

                            Details : Sio intends to return the global rights for AXO-Lenti-PD and that they intend to cease work on this gene therapy programme in Parkinson’s Disease. Sio is currently conducting a Phase 2 SUNRISE-PD trial with AXO-Lenti-PD.

                            Brand Name : OXB-102

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            January 31, 2022

                            Lead Product(s) : AXO-Lenti-PD

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Sio Gene Therapies

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            07

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                            Lead Product(s) : Tisagenlecleucel

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Novartis Pharmaceuticals Corporation

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Oxford Biomedica In License and Supply Deals With Novartis and Arcellx

                            Details : Under the terms of the agreement, Oxford Biomedica will receive payments related to the development and manufacturing of lentiviral vectors for use in clinical trials with also allowing for payments for the manufacture and supply of lentiviral vectors fo...

                            Brand Name : Kymriah

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            December 13, 2021

                            Lead Product(s) : Tisagenlecleucel

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Novartis Pharmaceuticals Corporation

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            08

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                            Lead Product(s) : ChAdOx1 nCoV-19

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved

                            Sponsor : AstraZeneca

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Oxford Biomedica Upgrades Financial Guidance for Supply Agreement With AstraZeneca for Manufacture of COVID-19...

                            Details : Oxford Biomedica announced an 18 month supply agreement in September 2020 under a three year Master Supply and Development Agreement with AstraZeneca for large-scale manufacture of the adenovirus vector-based COVID-19 vaccine, AZD1222.

                            Brand Name : AZD1222

                            Molecule Type : Vaccine

                            Upfront Cash : Undisclosed

                            May 18, 2021

                            Lead Product(s) : ChAdOx1 nCoV-19

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved

                            Sponsor : AstraZeneca

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            Lead Product(s) : LentiVector based gene therapy

                            Therapeutic Area : Oncology

                            Study Phase : Discovery

                            Recipient : PhoreMost

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            PhoreMost, Oxford Biomedica Enter Discovery Collaboration for Next-Gen CAR-T Therapies

                            Details : PhoreMost will deploy its in-house expertise and next-generation phenotypic screening platform, SITESEEKER®, to identify therapeutic candidates for Oxford Biomedica’s LentiVector® gene therapy delivery system.

                            Brand Name : Undisclosed

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            November 09, 2020

                            Lead Product(s) : LentiVector based gene therapy

                            Therapeutic Area : Oncology

                            Highest Development Status : Discovery

                            Recipient : PhoreMost

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            Lead Product(s) : AXO-Lenti-PD

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Recipient : Sio Gene Therapies

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Axovant Gene Therapies to Present AXO-Lenti-PD Program Update During Virtual Parkinson’s Disease R&D Day on ...

                            Details : AXO-Lenti-PD gene therapy demonstrate consistent treatment outcomes including Favorable safety and tolerability profile, with no serious adverse events attributable to gene therapy; Improvement in Hauser diary “Good ON time” and “OFF time” and ot...

                            Brand Name : OXB-102

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            October 29, 2020

                            Lead Product(s) : AXO-Lenti-PD

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Recipient : Sio Gene Therapies

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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