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Find Clinical Drug Pipeline Developments & Deals by Oxurion
Details :
Targets are derived from a cutting-edge CRISPR-based platform have successfully confirmed the potential of several of these targets across various relevant in vitro models of Geographic Atrophy.
Details :
THR-149 is a novel plasma kallikrein (PKal) inhibitor which is being evaluated under phase 2 clinical trials for the treatment of diabetic macular edema (DME).
Details :
The financing will be used for the development of THR-149, a bicyclic peptide that selectively inhibits human plasma kallikrein, for the treatment of patients with diabetic macular edema.
Details :
The financing from the agreement will enable Oxurion to progress the Phase 2, Part B KALAHARI trial of THR-149, a potent PKal inhibitor, in Diabetic Macular Edema (DME).
Details :
The financing will be used for the development of THR-149, a bicyclic peptide that selectively inhibits human plasma kallikrein, for the treatment of patients with diabetic macular edema.
Details :
Under the agreement, VIB acquired Oxurion's preclinical oncology asset and will use the upfront in the development of THR-149, being evaluated in a Phase 2 clinical trial as a potential treatment for of diabetic macular edema.
Details :
The net proceeds will be used to fund the Phase 2, KALAHARI trial evaluating Oxurion’s THR-149, a bicyclic peptide that selectively inhibits human plasma kallikrein, for treating the up to 50% of patients with diabetic macular edema (DME).
Details :
THR-149 is a bicyclic peptide that selectively inhibits human plasma kallikrein (PKal) with an inhibition constant of 0.22 nM. THR-149 is currently being evaluated for Diabetic Macular Edema.
Details :
THR-149 is a bicyclic peptide that selectively inhibits human plasma kallikrein (PKal) with an inhibition constant of 0.22 nM. Through the inhibition of the kallikrein-kinin system (KKS), THR-149 prevents the induction of retinal vascular permeability an...
Details :
The financing will be used to progress towards finishing patient recruitment for the Phase 2, Part B KALAHARI trial evaluating Oxurion’s THR-149 for treating the up to 50% of patients with diabetic macular edema (DME).
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