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    [{"orgOrder":0,"company":"Flexion Therapeutics","sponsor":"HK Tainuo","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Licensing Agreement","leadProduct":"Omadacycline","moa":"Glucocorticoid receptor","graph1":"Neurology","graph2":"Approved","graph3":"Flexion Therapeutics","amount2":0.040000000000000001,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Neurology","amount2New":0.040000000000000001,"dosageForm":"Intra-articular Injection","sponsorNew":"Flexion Therapeutics \/ HK Tainuo","highestDevelopmentStatusID":"12","companyTruncated":"Flexion Therapeutics \/ HK Tainuo"},{"orgOrder":0,"company":"Flexion Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Funapide","moa":"","graph1":"Neurology","graph2":"Preclinical","graph3":"Flexion 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I","therapeuticAreaShortName":"Musculoskeletal","amount2New":0,"dosageForm":"Intraarticular Injection","sponsorNew":"Flexion Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Flexion Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Pacira BioSciences","sponsor":"Eurofarma Laboratorios S.A","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Small molecule","year":"2021","type":"Agreement","leadProduct":"Bupivacaine","moa":"Sodium channel","graph1":"Neurology","graph2":"Approved","graph3":"Pacira BioSciences","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Injectable Suspension","sponsorNew":"Pacira BioSciences \/ Eurofarma","highestDevelopmentStatusID":"12","companyTruncated":"Pacira BioSciences \/ Eurofarma"},{"orgOrder":0,"company":"Pacira BioSciences","sponsor":"Flexion Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Small molecule","year":"2021","type":"Acquisition","leadProduct":"Triamcinolone Acetonide","moa":"Glucocorticoid receptor","graph1":"Neurology","graph2":"Approved","graph3":"Pacira BioSciences","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Intra-articular Injection","sponsorNew":"Pacira BioSciences \/ Pacira","highestDevelopmentStatusID":"12","companyTruncated":"Pacira BioSciences \/ Pacira"},{"orgOrder":0,"company":"Pacira BioSciences","sponsor":"Genascence","pharmaFlowCategory":"D","therapeuticArea":"Musculoskeletal","country":"U.S.A","productType":"Cell and Gene therapy","year":"2022","type":"Series A Financing","leadProduct":"sc-rAAV2.5IL-1Ra","moa":"","graph1":"Musculoskeletal","graph2":"Phase II","graph3":"Pacira BioSciences","amount2":0.01,"highestDevelopmentShortName":"Ph 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BioSciences","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"Pacira BioSciences \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Pacira BioSciences \/ Not Applicable"}]

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                            01

                            Pacira BioSciences

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                            Lead Product(s) : Enekinragene Inzadenovec

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Pacira Presents 104-Week Safety and Efficacy Data of PCRX-201 for Osteoarthritis

                            Details : PCRX-201 (enekinragene inzadenovec), is a adenoviral gene therapy vector codes for IL-1Ra expression, which is being evaluated for moderate to severe osteoarthritis of the knee.

                            Brand Name : PCRX-201

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            September 26, 2024

                            Lead Product(s) : Enekinragene Inzadenovec

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Pacira BioSciences

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                            Lead Product(s) : Enekinragene Inzadenovec

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Pacira Announces RMAT Designation for PCRX-201 in Osteoarthritis Treatment

                            Details : PCRX-201 (enekinragene inzadenovec) is a high-capacity gene therapy vector coding for IL-1Ra to block inflammation in osteoarthritis and disease progression.

                            Brand Name : PCRX-201

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            March 13, 2024

                            Lead Product(s) : Enekinragene Inzadenovec

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Pacira BioSciences

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                            Lead Product(s) : Bupivacaine

                            Therapeutic Area : Neurology

                            Study Phase : Approved

                            Sponsor : Premier

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Pacira BioSciences Awarded Brand Pharmaceuticals Agreement with Premier, Inc.

                            Details : Through the agreement, Premier will have access of EXPAREL (bupivacaine), a single-dose regional analgesic that provides prolonged postsurgical pain control while reducing reliance on opioids.

                            Brand Name : Exparel

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            February 07, 2024

                            Lead Product(s) : Bupivacaine

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved

                            Sponsor : Premier

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            04

                            Pacira BioSciences

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                            Pacira BioSciences

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                            Lead Product(s) : Bupivacaine

                            Therapeutic Area : Neurology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Pacira Announces FDA Approval of Expanded EXPAREL Label to Include Two Additional Nerve Block Indications

                            Details : EXPAREL® (bupivacaine liposome injectable suspension) expand label to include administration in adults as an adductor canal block and a sciatic nerve block in the popliteal fossa.

                            Brand Name : Exparel

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            November 10, 2023

                            Lead Product(s) : Bupivacaine

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Pacira BioSciences

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                            Pacira BioSciences

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                            Lead Product(s) : Bupivacaine

                            Therapeutic Area : Neurology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Pacira BioSciences Announces Positive Topline Data from Phase 3 Study of EXPAREL as a Single-Dose Sciatic Nerv...

                            Details : Second Phase 3 study of EXPAREL (bupivacaine) achieves primary and key secondary endpoints; safely demonstrating statistically significant reductions in postsurgical pain and opioid consumption through 96 hours.

                            Brand Name : Exparel

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 22, 2022

                            Lead Product(s) : Bupivacaine

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Pacira BioSciences

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                            Pacira BioSciences

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                            Lead Product(s) : Bupivacaine

                            Therapeutic Area : Neurology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Pacira BioSciences Announces Positive Topline Data from Phase 3 Study of EXPAREL as a Single-dose Femoral Nerv...

                            Details : EXPAREL achieved the study’s primary endpoint demonstrating a statistically significant reduction in cumulative pain scores from 0 to 96 hours compared with bupivacaine HCl (p<0.01).

                            Brand Name : Exparel

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 07, 2022

                            Lead Product(s) : Bupivacaine

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Pacira BioSciences

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                            Pacira BioSciences

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                            Lead Product(s) : sc-rAAV2.5IL-1Ra

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Phase II

                            Recipient : Genascence

                            Deal Size : $10.5 million

                            Deal Type : Series A Financing

                            DEALS_DEV arrow-down

                            Genascence Announces First Close in Series A Financing led by Pacira BioSciences and Expands Board of Director...

                            Details : GNSC-001 is an adeno-associated vector (AAV) carrying a coding sequence for interleukin-1 receptor antagonist (IL-1Ra), a potent inhibitor of interleukin-1 (IL-1) signaling.

                            Brand Name : GNSC-001

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            May 10, 2022

                            Lead Product(s) : sc-rAAV2.5IL-1Ra

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Phase II

                            Recipient : Genascence

                            Deal Size : $10.5 million

                            Deal Type : Series A Financing

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                            08

                            Pacira BioSciences

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                            Pacira BioSciences

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                            Lead Product(s) : Triamcinolone Acetonide

                            Therapeutic Area : Neurology

                            Study Phase : Approved

                            Recipient : Flexion Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Pacira BioSciences to Acquire Flexion Therapeutics Further Expanding Leadership Position in Non-Opioid Pain Ma...

                            Details : This acquisition is a major milestone to build a robust offering of novel, non-opioid treatments to improve patient care along the neural pain pathway while simultaneously providing a complementary commercial asset in ZILRETTA for the treatment of OA kne...

                            Brand Name : Zilretta

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            October 11, 2021

                            Lead Product(s) : Triamcinolone Acetonide

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved

                            Recipient : Flexion Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            09

                            Pacira BioSciences

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                            Pacira BioSciences

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                            Lead Product(s) : Bupivacaine

                            Therapeutic Area : Neurology

                            Study Phase : Approved

                            Sponsor : Eurofarma Laboratorios S.A

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Pacira BioSciences Signs Exparel Distribution Agreement With Eurofarma in Latin America

                            Details : Under the terms of the agreement, Eurofarma obtains the exclusive right to market and distribute EXPAREL in 19 countries in Latin America, including Argentina, Brazil, Colombia, and Mexico.

                            Brand Name : Exparel

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            June 22, 2021

                            Lead Product(s) : Bupivacaine

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved

                            Sponsor : Eurofarma Laboratorios S.A

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            10

                            Flexion Therapeutics

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                            Lead Product(s) : Humantakinogene hadenovec

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Flexion Therapeutics to Advance Investigational Gene Therapy FX201 into High Dose Cohort of Phase 1 Clinical T...

                            Details : Company to expand FX201 low dose and mid dose cohorts to include up to 20 additional patients in each treatment group. Clinical data from the first two cohorts indicate that FX201 appears to be generally safe and well-tolerated at the low and mid doses.

                            Brand Name : FX201

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            February 18, 2021

                            Lead Product(s) : Humantakinogene hadenovec

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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