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    [{"orgOrder":0,"company":"Flexion Therapeutics","sponsor":"HK Tainuo","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Licensing Agreement","leadProduct":"Omadacycline","moa":"Glucocorticoid receptor","graph1":"Neurology","graph2":"Approved","graph3":"Flexion Therapeutics","amount2":0.040000000000000001,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Neurology","amount2New":0.040000000000000001,"dosageForm":"Intra-articular Injection","sponsorNew":"Flexion Therapeutics \/ HK Tainuo","highestDevelopmentStatusID":"12","companyTruncated":"Flexion Therapeutics \/ HK Tainuo"},{"orgOrder":0,"company":"Flexion Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Funapide","moa":"","graph1":"Neurology","graph2":"Preclinical","graph3":"Flexion 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BioSciences","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Bupivacaine","moa":"Sodium channel","graph1":"Neurology","graph2":"Approved","graph3":"Pacira BioSciences","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Injectable Suspension","sponsorNew":"Pacira BioSciences \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Pacira BioSciences \/ Not Applicable"},{"orgOrder":0,"company":"Flexion Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Musculoskeletal","country":"U.S.A","productType":"Cell and Gene therapy","year":"2020","type":"Not Applicable","leadProduct":"Humantakinogene hadenovec","moa":"IL-1 receptor","graph1":"Musculoskeletal","graph2":"Phase I","graph3":"Flexion Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Musculoskeletal","amount2New":0,"dosageForm":"Injection","sponsorNew":"Flexion Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Flexion Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Pacira BioSciences","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Bupivacaine","moa":"Sodium channel","graph1":"Neurology","graph2":"Approved","graph3":"Pacira BioSciences","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Injectable Suspension","sponsorNew":"Pacira BioSciences \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Pacira BioSciences \/ Not Applicable"},{"orgOrder":0,"company":"Flexion Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Funapide","moa":"","graph1":"Neurology","graph2":"Preclinical","graph3":"Flexion Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Hydrogel","sponsorNew":"Flexion Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"4","companyTruncated":"Flexion Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Flexion Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Musculoskeletal","country":"U.S.A","productType":"Cell and Gene therapy","year":"2021","type":"Not Applicable","leadProduct":"Humantakinogene hadenovec","moa":"IL-1 receptor","graph1":"Musculoskeletal","graph2":"Phase I","graph3":"Flexion Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Musculoskeletal","amount2New":0,"dosageForm":"Intraarticular Injection","sponsorNew":"Flexion Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Flexion Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Pacira BioSciences","sponsor":"Eurofarma Laboratorios S.A","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Small molecule","year":"2021","type":"Agreement","leadProduct":"Bupivacaine","moa":"Sodium channel","graph1":"Neurology","graph2":"Approved","graph3":"Pacira BioSciences","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Injectable Suspension","sponsorNew":"Pacira BioSciences \/ Eurofarma Laboratorios S.A","highestDevelopmentStatusID":"12","companyTruncated":"Pacira BioSciences \/ Eurofarma Laboratorios S.A"},{"orgOrder":0,"company":"Pacira BioSciences","sponsor":"Flexion Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Small molecule","year":"2021","type":"Acquisition","leadProduct":"Triamcinolone Acetonide","moa":"Glucocorticoid receptor","graph1":"Neurology","graph2":"Approved","graph3":"Pacira BioSciences","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Intra-articular Injection","sponsorNew":"Pacira BioSciences \/ Pacira BioSciences","highestDevelopmentStatusID":"12","companyTruncated":"Pacira BioSciences \/ Pacira BioSciences"},{"orgOrder":0,"company":"Pacira BioSciences","sponsor":"Genascence","pharmaFlowCategory":"D","therapeuticArea":"Musculoskeletal","country":"U.S.A","productType":"Cell and Gene therapy","year":"2022","type":"Series A Financing","leadProduct":"sc-rAAV2.5IL-1Ra","moa":"","graph1":"Musculoskeletal","graph2":"Phase II","graph3":"Pacira BioSciences","amount2":0.01,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Musculoskeletal","amount2New":0.01,"dosageForm":"Inhalation","sponsorNew":"Pacira BioSciences \/ Pacira BioSciences","highestDevelopmentStatusID":"8","companyTruncated":"Pacira BioSciences \/ Pacira BioSciences"},{"orgOrder":0,"company":"Pacira BioSciences","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Small molecule","year":"2022","type":"Not Applicable","leadProduct":"Bupivacaine","moa":"SCN10A","graph1":"Neurology","graph2":"Approved","graph3":"Pacira BioSciences","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Prolonged-release Suspension for Injection","sponsorNew":"Pacira BioSciences \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Pacira BioSciences \/ Not Applicable"},{"orgOrder":0,"company":"Pacira BioSciences","sponsor":"Not 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BioSciences","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Suspension, Liposomal","sponsorNew":"Pacira BioSciences \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Pacira BioSciences \/ Not Applicable"},{"orgOrder":0,"company":"Pacira BioSciences","sponsor":"Premier","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Small molecule","year":"2024","type":"Agreement","leadProduct":"Bupivacaine","moa":"","graph1":"Neurology","graph2":"Approved","graph3":"Pacira BioSciences","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Pacira BioSciences \/ Premier","highestDevelopmentStatusID":"12","companyTruncated":"Pacira BioSciences \/ Premier"},{"orgOrder":0,"company":"Pacira BioSciences","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Musculoskeletal","country":"U.S.A","productType":"Cell and Gene therapy","year":"2024","type":"Not Applicable","leadProduct":"Enekinragene Inzadenovec","moa":"","graph1":"Musculoskeletal","graph2":"Phase I","graph3":"Pacira BioSciences","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Musculoskeletal","amount2New":0,"dosageForm":"","sponsorNew":"Pacira BioSciences \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Pacira BioSciences \/ Not Applicable"},{"orgOrder":0,"company":"Pacira BioSciences","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Musculoskeletal","country":"U.S.A","productType":"Cell and Gene therapy","year":"2024","type":"Not Applicable","leadProduct":"Enekinragene Inzadenovec","moa":"","graph1":"Musculoskeletal","graph2":"Phase I","graph3":"Pacira BioSciences","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Musculoskeletal","amount2New":0,"dosageForm":"","sponsorNew":"Pacira BioSciences \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Pacira BioSciences \/ Not Applicable"},{"orgOrder":0,"company":"Pacira BioSciences","sponsor":"Kineta","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Large Molecule","year":"2025","type":"Agreement","leadProduct":"KCP506","moa":"Alpha 9\/10 nAChR","graph1":"Neurology","graph2":"Phase I","graph3":"Pacira BioSciences","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Pacira BioSciences \/ Pacira BioSciences","highestDevelopmentStatusID":"6","companyTruncated":"Pacira BioSciences \/ Pacira BioSciences"},{"orgOrder":0,"company":"Pacira BioSciences","sponsor":"GQ Bio Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Musculoskeletal","country":"GERMANY","productType":"Cell and Gene therapy","year":"2025","type":"Acquisition","leadProduct":"GQ-501","moa":"PRG4","graph1":"Musculoskeletal","graph2":"IND Enabling","graph3":"Pacira BioSciences","amount2":0.029999999999999999,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Musculoskeletal","amount2New":0.029999999999999999,"dosageForm":"Intra-articular Injection","sponsorNew":"Pacira BioSciences \/ Pacira BioSciences","highestDevelopmentStatusID":"5","companyTruncated":"Pacira BioSciences \/ Pacira BioSciences"}]

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                            01

                            Pacira BioSciences

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                            Lead Product(s) : GQ-501

                            Therapeutic Area : Musculoskeletal

                            Study Phase : IND Enabling

                            Recipient : GQ Bio Therapeutics

                            Deal Size : $32.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Pacira BioSciences Acquires Remaining Equity Stake of GQ Bio

                            Details : Through the acquisition, Pacira will leverage musculoskeletal portfolio, which includes GQ-501 is a helper-dependent adenoviral vector expressing proteoglycan 4 & being developed for osteoarthritis.

                            Product Name : GQ-501

                            Product Type : Cell and Gene therapy

                            Upfront Cash : $18.0 million

                            February 27, 2025

                            Lead Product(s) : GQ-501

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : IND Enabling

                            Recipient : GQ Bio Therapeutics

                            Deal Size : $32.0 million

                            Deal Type : Acquisition

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                            02

                            Pacira BioSciences

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                            Lead Product(s) : KCP506

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Recipient : Kineta

                            Deal Size : $0.4 million

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Kineta Entered Into an Asset Purchase Agreement with Pacira Pharmaceuticals

                            Details : Under the agreement, Pacira will hold the exclusive rights for the development of KCP506, a product candidate for pain treatment.

                            Product Name : KCP506

                            Product Type : Other Large Molecule

                            Upfront Cash : Undisclosed

                            February 04, 2025

                            Lead Product(s) : KCP506

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Recipient : Kineta

                            Deal Size : $0.4 million

                            Deal Type : Agreement

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                            03

                            Pacira BioSciences

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                            Lead Product(s) : Enekinragene Inzadenovec

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Pacira Presents 104-Week Safety and Efficacy Data of PCRX-201 for Osteoarthritis

                            Details : PCRX-201 (enekinragene inzadenovec), is a adenoviral gene therapy vector codes for IL-1Ra expression, which is being evaluated for moderate to severe osteoarthritis of the knee.

                            Product Name : PCRX-201

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            September 26, 2024

                            Lead Product(s) : Enekinragene Inzadenovec

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Pacira BioSciences

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                            Lead Product(s) : Enekinragene Inzadenovec

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Pacira Announces RMAT Designation for PCRX-201 in Osteoarthritis Treatment

                            Details : PCRX-201 (enekinragene inzadenovec) is a high-capacity gene therapy vector coding for IL-1Ra to block inflammation in osteoarthritis and disease progression.

                            Product Name : PCRX-201

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            March 13, 2024

                            Lead Product(s) : Enekinragene Inzadenovec

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Pacira BioSciences

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                            Lead Product(s) : Bupivacaine

                            Therapeutic Area : Neurology

                            Study Phase : Approved

                            Sponsor : Premier

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Pacira BioSciences Awarded Brand Pharmaceuticals Agreement with Premier, Inc.

                            Details : Through the agreement, Premier will have access of EXPAREL (bupivacaine), a single-dose regional analgesic that provides prolonged postsurgical pain control while reducing reliance on opioids.

                            Product Name : Exparel

                            Product Type : Small molecule

                            Upfront Cash : Undisclosed

                            February 07, 2024

                            Lead Product(s) : Bupivacaine

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved

                            Sponsor : Premier

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            06

                            Pacira BioSciences

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                            Lead Product(s) : Bupivacaine

                            Therapeutic Area : Neurology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Pacira Announces FDA Approval of Expanded EXPAREL Label to Include Two Additional Nerve Block Indications

                            Details : EXPAREL® (bupivacaine liposome injectable suspension) expand label to include administration in adults as an adductor canal block and a sciatic nerve block in the popliteal fossa.

                            Product Name : Exparel

                            Product Type : Small molecule

                            Upfront Cash : Not Applicable

                            November 10, 2023

                            Lead Product(s) : Bupivacaine

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Pacira BioSciences

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                            Lead Product(s) : Bupivacaine

                            Therapeutic Area : Neurology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Pacira BioSciences Announces Positive Topline Data from Phase 3 Study of EXPAREL as a Single-Dose Sciatic Nerv...

                            Details : Second Phase 3 study of EXPAREL (bupivacaine) achieves primary and key secondary endpoints; safely demonstrating statistically significant reductions in postsurgical pain and opioid consumption through 96 hours.

                            Product Name : Exparel

                            Product Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 22, 2022

                            Lead Product(s) : Bupivacaine

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            Pacira BioSciences

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                            Lead Product(s) : Bupivacaine

                            Therapeutic Area : Neurology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Pacira BioSciences Announces Positive Topline Data from Phase 3 Study of EXPAREL as a Single-dose Femoral Nerv...

                            Details : EXPAREL achieved the study’s primary endpoint demonstrating a statistically significant reduction in cumulative pain scores from 0 to 96 hours compared with bupivacaine HCl (p<0.01).

                            Product Name : Exparel

                            Product Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 07, 2022

                            Lead Product(s) : Bupivacaine

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Pacira BioSciences

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                            BePharma
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                            Lead Product(s) : sc-rAAV2.5IL-1Ra

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Phase II

                            Recipient : Genascence

                            Deal Size : $10.5 million

                            Deal Type : Series A Financing

                            DEALS_DEV arrow-down

                            Genascence Announces First Close in Series A Financing led by Pacira BioSciences and Expands Board of Director...

                            Details : GNSC-001 is an adeno-associated vector (AAV) carrying a coding sequence for interleukin-1 receptor antagonist (IL-1Ra), a potent inhibitor of interleukin-1 (IL-1) signaling.

                            Product Name : GNSC-001

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            May 10, 2022

                            Lead Product(s) : sc-rAAV2.5IL-1Ra

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Phase II

                            Recipient : Genascence

                            Deal Size : $10.5 million

                            Deal Type : Series A Financing

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                            10

                            Pacira BioSciences

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                            Lead Product(s) : Triamcinolone Acetonide

                            Therapeutic Area : Neurology

                            Study Phase : Approved

                            Recipient : Flexion Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Pacira BioSciences to Acquire Flexion Therapeutics Further Expanding Leadership Position in Non-Opioid Pain Ma...

                            Details : This acquisition is a major milestone to build a robust offering of novel, non-opioid treatments to improve patient care along the neural pain pathway while simultaneously providing a complementary commercial asset in ZILRETTA for the treatment of OA kne...

                            Product Name : Zilretta

                            Product Type : Small molecule

                            Upfront Cash : Undisclosed

                            October 11, 2021

                            Lead Product(s) : Triamcinolone Acetonide

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved

                            Recipient : Flexion Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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