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Find Clinical Drug Pipeline Developments & Deals for Palazestrant

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                          Top Deals by Deal Size (USD bn)

                          01

                          BioAsia
                          Not Confirmed
                          BioAsia
                          Not Confirmed

                          Details : Through collaboration, Novartis will provide Olema with ribociclib for the planned late-stage OP-1250 (palazestrant) trial with ribociclib in ER+/HER2-metastatic breast cancer.

                          Product Name : OP-1250

                          Product Type : Small molecule

                          Upfront Cash : Undisclosed

                          December 02, 2024

                          Lead Product(s) : Palazestrant,Ribociclib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Novartis Pharmaceuticals Corporation

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          02

                          BioAsia
                          Not Confirmed
                          BioAsia
                          Not Confirmed

                          Details : The net proceeds will be used to fund the clinical development of company's lead product OP-1250 (palazestrant), which is being evaluated for the treatment of ER+/HER2-metastatic breast cancer.

                          Product Name : OP-1250

                          Product Type : Small molecule

                          Upfront Cash : Undisclosed

                          December 02, 2024

                          Lead Product(s) : Palazestrant,Ribociclib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Adage Capital Partners LP

                          Deal Size : $250.0 million

                          Deal Type : Private Placement

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                          03

                          BioAsia
                          Not Confirmed
                          BioAsia
                          Not Confirmed

                          Details : Under the collaboration, Novartis will increase the size of the ongoing Phase 1/2 study testing OP-1250 (palazestrant), an orally-available small molecule with dual activity as both a complete ER antagonist and a selective ER degrader, in combination wit...

                          Product Name : OP-1250

                          Product Type : Small molecule

                          Upfront Cash : Undisclosed

                          October 10, 2023

                          Lead Product(s) : Palazestrant,Ribociclib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Novartis Pharmaceuticals Corporation

                          Deal Size : Undisclosed

                          Deal Type : Expanded Collaboration

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                          04

                          BioAsia
                          Not Confirmed
                          BioAsia
                          Not Confirmed

                          Details : Olema intends to use the net proceeds to fund research and development of palazestrant OP-1250 (palazestrant), a proprietary, orally-available small molecule with dual activity as both a complete estrogen receptor (ER) antagonist and a selective ER degra...

                          Product Name : OP-1250

                          Product Type : Small molecule

                          Upfront Cash : Undisclosed

                          September 05, 2023

                          Lead Product(s) : Palazestrant,Palbociclib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Paradigm BioCapital

                          Deal Size : $130.0 million

                          Deal Type : Private Placement

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