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Details:
Under the collaboration, Novartis will increase the size of the ongoing Phase 1/2 study testing OP-1250 (palazestrant), an orally-available small molecule with dual activity as both a complete ER antagonist and a selective ER degrader, in combination with ribociclib.
Lead Product(s): Palazestrant,Ribociclib
Therapeutic Area: Oncology Product Name: OP-1250
Highest Development Status: Phase I Product Type: Small molecule
Partner/Sponsor/Collaborator: Novartis Pharmaceuticals Corporation
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Expanded Collaboration October 10, 2023
Details:
Olema intends to use the net proceeds to fund research and development of palazestrant OP-1250 (palazestrant), a proprietary, orally-available small molecule with dual activity as both a complete estrogen receptor (ER) antagonist and a selective ER degrader.
Lead Product(s): Palazestrant,Palbociclib
Therapeutic Area: Oncology Product Name: OP-1250
Highest Development Status: Phase I Product Type: Small molecule
Partner/Sponsor/Collaborator: Paradigm BioCapital
Deal Size: $130.0 million Upfront Cash: Undisclosed
Deal Type: Private Placement September 05, 2023