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    [{"orgOrder":0,"company":"Crinetics Pharmaceuticals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Paltusotine","moa":"","graph1":"Endocrinology","graph2":"Phase II","graph3":"Crinetics Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Crinetics Pharmaceuticals \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Crinetics Pharmaceuticals \/ Not Applicable"},{"orgOrder":0,"company":"Crinetics Pharmaceuticals","sponsor":"SVB Leerink","pharmaFlowCategory":"D","therapeuticArea":"Endocrinology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Public Offering","leadProduct":"Paltusotine","moa":"","graph1":"Endocrinology","graph2":"Phase III","graph3":"Crinetics 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Pharmaceuticals","amount2":0.46000000000000002,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"Crinetics Pharmaceuticals \/ Leerink Partners","highestDevelopmentStatusID":"12","companyTruncated":"Crinetics Pharmaceuticals \/ Leerink Partners"}]

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                            01

                            Crinetics Pharmaceuticals

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                            Lead Product(s) : Paltusotine

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase III

                            Sponsor : Leerink Partners

                            Deal Size : $500.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Crinetics Pharmaceuticals Announces Pricing of Upsized Public Offering of Common Stock

                            Details : The company will fund research and development of its clinical stage product candidates, including CRN00808 (paltusotine), first once-daily, oral, SST2 agonist in development for acromegaly.

                            Brand Name : CRN00808

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            October 08, 2024

                            Lead Product(s) : Paltusotine

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase III

                            Sponsor : Leerink Partners

                            Deal Size : $500.0 million

                            Deal Type : Public Offering

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                            02

                            Crinetics Pharmaceuticals

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                            Lead Product(s) : Paltusotine

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase III

                            Sponsor : Leerink Partners

                            Deal Size : $460.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Crinetics Pharmaceuticals Announces Proposed Public Offering of Common Stock

                            Details : The company will fund research and development of its clinical stage product candidates, including CRN00808 (paltusotine), first once-daily, oral, SST2 agonist in development for acromegaly.

                            Brand Name : CRN00808

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            October 08, 2024

                            Lead Product(s) : Paltusotine

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase III

                            Sponsor : Leerink Partners

                            Deal Size : $460.0 million

                            Deal Type : Public Offering

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                            03

                            Crinetics Pharmaceuticals

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                            Lead Product(s) : Paltusotine

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Crinetics Submits New Drug Application for Paltusotine for the Treatment of Acromegaly

                            Details : CRN00808 (paltusotine) is an oral selective nonpeptide somatostatin receptor type 2 biased agonist, being evaluated for the treatment of patients with non-pharmacologically treated acromegaly.

                            Brand Name : CRN00808

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 26, 2024

                            Lead Product(s) : Paltusotine

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Crinetics Pharmaceuticals

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                            Lead Product(s) : Paltusotine

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Crinetics’ Paltusotine Achieves Primary and All Secondary Endpoints for Acromegaly

                            Details : CRN00808 (paltusotine) is an oral selective nonpeptide somatostatin receptor type 2 biased agonist, being evaluated for the treatment of patients with non-pharmacologically treated acromegaly.

                            Brand Name : CRN00808

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            March 19, 2024

                            Lead Product(s) : Paltusotine

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Crinetics Pharmaceuticals

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                            Crinetics Pharmaceuticals

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                            Lead Product(s) : Paltusotine

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Crinetics Reports Positive Topline Data from Phase 2 of Paltusotine for Carcinoid Syndrome

                            Details : Crinetics lead product candidate CRN00808 (paltusotine), an SST2 agonist. Currently, it is being evaluated in the Phase II clinical trial studies for the treatment of Carcinoid Syndrome.

                            Brand Name : CRN00808

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            March 12, 2024

                            Lead Product(s) : Paltusotine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Crinetics Pharmaceuticals

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                            Lead Product(s) : Paltusotine

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase III

                            Sponsor : Adage Capital Partners

                            Deal Size : $350.0 million

                            Deal Type : Private Placement

                            DEALS_DEV arrow-down

                            Crinetics Pharmaceuticals Announces Oversubscribed $350 Million Private Placement

                            Details : Crinetics intends to use the net proceeds from the private placement to fund research and development of its clinical-stage product CRN00808 (paltusotine) for Acromegaly rare hormonal disorder.

                            Brand Name : CRN00808

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            February 28, 2024

                            Lead Product(s) : Paltusotine

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase III

                            Sponsor : Adage Capital Partners

                            Deal Size : $350.0 million

                            Deal Type : Private Placement

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                            07

                            Crinetics Pharmaceuticals

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                            Crinetics Pharmaceuticals

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                            Lead Product(s) : Paltusotine

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Crinetics Announces Positive Initial Findings from Ongoing Open-Label Phase 2 Study of Paltusotine for the Tre...

                            Details : CRN-00808 (paltusotine) is the first oral, once-daily selectively-targeted somatostatin receptor type 2 (SST2) agonist and is currently in investigational Phase 3 studies for acromegaly and a Phase 2 study for carcinoid syndrome.

                            Brand Name : CRN-00808

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            December 18, 2023

                            Lead Product(s) : Paltusotine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            Crinetics Pharmaceuticals

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                            Lead Product(s) : Paltusotine

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase III

                            Sponsor : J.P. Morgan

                            Deal Size : $350.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Crinetics Pharmaceuticals Announces Pricing of Upsized Public Offering of Common Stock

                            Details : The proceeds will fund development of CRN00808 (paltusotine), a small molecule SST2 agonist, in Phase 3 for acromegaly and Phase 2 for carcinoid syndrome and CRN04894, a small molecule ACTH antagonist, in Phase 2 for Cushing’s disease and congenital ad...

                            Brand Name : CRN00808

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            September 12, 2023

                            Lead Product(s) : Paltusotine

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase III

                            Sponsor : J.P. Morgan

                            Deal Size : $350.0 million

                            Deal Type : Public Offering

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                            09

                            Crinetics Pharmaceuticals

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                            Lead Product(s) : Paltusotine

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase III

                            Sponsor : J.P. Morgan

                            Deal Size : $250.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Crinetics Pharmaceuticals Announces Proposed Public Offering of Common Stock

                            Details : The proceeds will fund development of CRN00808 (paltusotine), a small molecule SST2 agonist, in Phase 3 for acromegaly and Phase 2 for carcinoid syndrome and CRN04894, a small molecule ACTH antagonist, in Phase 2 for Cushing’s disease and congenital ad...

                            Brand Name : CRN00808

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            September 11, 2023

                            Lead Product(s) : Paltusotine

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase III

                            Sponsor : J.P. Morgan

                            Deal Size : $250.0 million

                            Deal Type : Public Offering

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                            Crinetics Pharmaceuticals

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                            Lead Product(s) : Paltusotine

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Crinetics’ Once-Daily Oral Paltusotine Achieved The Primary and All Secondary Endpoints in The Phase 3 Pathf...

                            Details : CRN00808 (paltusotine) is the first oral, once-daily selectively targeted somatostatin receptor type 2 (SST2) agonist and is currently in Phase 3 investigational studies for acromegaly.

                            Brand Name : CRN00808

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 10, 2023

                            Lead Product(s) : Paltusotine

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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