[{"orgOrder":0,"company":"Adlai Nortye","sponsor":"Merck & Co","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Palupiprant","moa":"||EP4 receptor","graph1":"Oncology","graph2":"Phase I","graph3":"Adlai Nortye","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Adlai Nortye \/ Merck & Co","highestDevelopmentStatusID":"6","companyTruncated":"Adlai Nortye \/ Merck & Co"},{"orgOrder":0,"company":"Adlai Nortye","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Palupiprant","moa":"EP4 receptor","graph1":"Oncology","graph2":"Phase II","graph3":"Adlai Nortye","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Adlai Nortye \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Adlai Nortye \/ Inapplicable"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          WRIB
                          Not Confirmed
                          WRIB
                          Not Confirmed

                          Details : AN0025 is a small molecule prostaglandin E receptor 4 antagonist, which is being in the phase II clinical trials studies for the treatment of locally advanced rectal cancer.

                          Product Name : AN0025

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          May 22, 2024

                          Lead Product(s) : Palupiprant

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          WRIB
                          Not Confirmed
                          WRIB
                          Not Confirmed

                          Details : First patient has been dosed in a phase 1b clinical trial (AN0025S0103) to evaluate AN0025, an investigational, potentially first in class oral EP4 antagonist, in combination with Merck's KEYTRUDA® (pembrolizumab) in patients with locally advanced/metas...

                          Product Name : AN0025

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          August 24, 2020

                          Lead Product(s) : Palupiprant,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Merck & Co

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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