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    [{"orgOrder":0,"company":"Palvella Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"U.S.A","productType":"Antibiotic","year":"2025","type":"Inapplicable","leadProduct":"Sirolimus","moa":"mTOR","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase II","graph3":"Palvella Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Topical Gel","sponsorNew":"Palvella Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Palvella Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Palvella Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibiotic","year":"2023","type":"Inapplicable","leadProduct":"Sirolimus","moa":"mTOR","graph1":"Oncology","graph2":"Phase III","graph3":"Palvella Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Topical Gel","sponsorNew":"Palvella Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Palvella Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Palvella Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibiotic","year":"2023","type":"Inapplicable","leadProduct":"Sirolimus","moa":"mTOR","graph1":"Oncology","graph2":"Phase III","graph3":"Palvella Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Topical Gel","sponsorNew":"Palvella Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Palvella Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Palvella Therapeutics","sponsor":"Ligand 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Diseases and Disorders","country":"U.S.A","productType":"Antibiotic","year":"2025","type":"Inapplicable","leadProduct":"Sirolimus","moa":"mTOR","graph1":"Rare Diseases and Disorders","graph2":"Phase III","graph3":"Palvella Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Rare Diseases","amount2New":0,"dosageForm":"Topical Gel","sponsorNew":"Palvella Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Palvella Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Palvella Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Antibiotic","year":"2023","type":"Inapplicable","leadProduct":"Sirolimus","moa":"mTOR","graph1":"Genetic Disease","graph2":"Phase III","graph3":"Palvella Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Topical 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Financing","leadProduct":"Sirolimus","moa":"mTOR","graph1":"Genetic Disease","graph2":"Phase III","graph3":"Palvella Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Topical Gel","sponsorNew":"Palvella Therapeutics \/ Petrichor Healthcare","highestDevelopmentStatusID":"10","companyTruncated":"Palvella Therapeutics \/ Petrichor Healthcare"}]

    Find Clinical Drug Pipeline Developments & Deals by Palvella Therapeutics

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                            01

                            Palvella Therapeutics

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                            Lead Product(s) : Sirolimus

                            Therapeutic Area : Rare Diseases and Disorders

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Palvella Expands Phase 3 SELVA Trial of Qtorin Rapamycin Gel to Younger Kids

                            Details : Qtorin rapamycin has the potential to be the first approved therapy and standard of care in the U.S. for the treatment of microcystic lymphatic malformations.

                            Product Name : Qtorin Rapamycin

                            Product Type : Antibiotic

                            Upfront Cash : Inapplicable

                            February 10, 2025

                            Lead Product(s) : Sirolimus

                            Therapeutic Area : Rare Diseases and Disorders

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Palvella Therapeutics

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                            Lead Product(s) : Sirolimus

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Palvella Doses First Patients in Phase 2 QTORIN Rapamycin Trial for Venous Malformations

                            Details : Qtorin (rapamycin) is a macrocyclic lactone antibiotic produced by bacteria Streptomyces hygroscopicus. It is being evaluated for the treatment of cutaneous venous malformations.

                            Product Name : Qtorin

                            Product Type : Antibiotic

                            Upfront Cash : Inapplicable

                            January 08, 2025

                            Lead Product(s) : Sirolimus

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Palvella Therapeutics

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                            Palvella Therapeutics

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                            Lead Product(s) : Sirolimus

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : BVF Partners

                            Deal Size : $78.9 million

                            Deal Type : Private Placement

                            DEALS_DEV arrow-down

                            Palvella Merges with Pieris and Raises $78.9M in Concurrent Private Placement

                            Details : The financing will be used to fund the clinical development of the company's lead product Qtorin (Rapamycin), which is being evaluated for the treatment of Microcystic Lymphatic Malformations.

                            Product Name : Qtorin

                            Product Type : Antibiotic

                            Upfront Cash : Undisclosed

                            December 13, 2024

                            Lead Product(s) : Sirolimus

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : BVF Partners

                            Deal Size : $78.9 million

                            Deal Type : Private Placement

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                            04

                            Palvella Therapeutics

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                            Palvella Therapeutics

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                            Lead Product(s) : SGN-BB228

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Pieris Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Merger

                            DEALS_DEV arrow-down

                            Palvella Closes Pieris Merger and $78.9M Private Placement

                            Details : Through the merger, Palvella will acquire the Pieris pipeline, including oncology products such as PRS-346 (SGN-BB228), which is being evaluated for the treatment of advanced melanoma.

                            Product Name : PRS-346

                            Product Type : Other Large Molecule

                            Upfront Cash : Undisclosed

                            December 13, 2024

                            Lead Product(s) : SGN-BB228

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Pieris Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Merger

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                            05

                            Palvella Therapeutics

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                            Palvella Therapeutics

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                            Lead Product(s) : Sirolimus

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Palvella Therapeutics Doses First Patient in SELVA Trial for Lymphatic Malformations

                            Details : Qtorin (rapamycin) is a macrocyclic lactone antibiotic produced by bacteria Streptomyces hygroscopicus. It is being evaluated for the treatment of microcystic lymphatic malformations.

                            Product Name : Qtorin

                            Product Type : Antibiotic

                            Upfront Cash : Inapplicable

                            July 11, 2024

                            Lead Product(s) : Sirolimus

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Palvella Therapeutics

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                            Palvella Therapeutics

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                            Lead Product(s) : Sirolimus

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : FDA

                            Deal Size : $2.6 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Palvella Wins $2.6M FDA Grant for Phase 3 Trial in Microcystic Lymphatic Malformations

                            Details : The proceeds will support the ongoing Phase 3 of QTORIN rapamycin anhydrous gel for the treatment of microcystic lymphatic malformations (microcystic LMs).

                            Product Name : Qtorin

                            Product Type : Antibiotic

                            Upfront Cash : Undisclosed

                            March 10, 2024

                            Lead Product(s) : Sirolimus

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : FDA

                            Deal Size : $2.6 million

                            Deal Type : Funding

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                            07

                            Palvella Therapeutics

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                            Palvella Therapeutics

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                            Lead Product(s) : Sirolimus

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Palvella Therapeutics Announces U.S. FDA Breakthrough Therapy Designation Granted to QTORIN™ 3.9% Rapamycin ...

                            Details : Qtorin (rapamycin) is a macrocyclic lactone antibiotic produced by bacteria Streptomyces hygroscopicus. It is being evaluated for the treatment of microcystic lymphatic malformations.

                            Product Name : Qtorin

                            Product Type : Antibiotic

                            Upfront Cash : Inapplicable

                            November 16, 2023

                            Lead Product(s) : Sirolimus

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Palvella Therapeutics

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                            Palvella Therapeutics

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                            Lead Product(s) : Sirolimus

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Palvella Therapeutics Announces Positive Topline Results from Phase 2 Study of QTORIN 3.9% Rapamycin Anhydrous...

                            Details : Qtorin™ (rapamycin) is the lead product candidate from Palvella’s QTORIN™ platform and is initially under evaluation for for the treatment of individuals with Pachyonychia Congenita and Microcystic LM, as well as for the prevention of BCCs in indiv...

                            Product Name : Qtorin

                            Product Type : Antibiotic

                            Upfront Cash : Inapplicable

                            September 03, 2023

                            Lead Product(s) : Sirolimus

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Palvella Therapeutics

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                            Palvella Therapeutics

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                            Lead Product(s) : Sirolimus

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Palvella Therapeutics Announces Planned Pivotal Phase 3 Study Design of QTORIN™ 3.9% Rapamycin Anhydrous Gel...

                            Details : Qtorin (rapamycin) a topical mTOR inhibitor, which is being investigated for the treatment of microcystic lymphatic malformations and in individuals with basal cell carcinomas (BCCs) in gorlin syndrome (GS).

                            Product Name : Qtorin

                            Product Type : Antibiotic

                            Upfront Cash : Inapplicable

                            July 20, 2023

                            Lead Product(s) : Sirolimus

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Palvella Therapeutics

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                            Palvella Therapeutics

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                            Lead Product(s) : Sirolimus

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Palvella Therapeutics Reports Topline Results from Pivotal Phase 3 VAPAUS Study of QTORIN™ 3.9% Rapamycin An...

                            Details : Qtorin (rapamycin), a topical mTOR inhibitor and the lead product candidate from the QTORIN™ platform, is being investigated in Phase 3 clinical trial for the treatment of Pachyonychia Congenita (PC).

                            Product Name : Qtorin

                            Product Type : Antibiotic

                            Upfront Cash : Inapplicable

                            July 20, 2023

                            Lead Product(s) : Sirolimus

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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