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                          01

                          BePharma
                          Not Confirmed
                          BePharma
                          Not Confirmed

                          Details : CPP-1X-S (eflornithine) sachets is an ornithine decarboxylase inhibitor being evaluated in the IND stage for treating STK11 mutant non-small cell lung cancer (NSCLC).

                          Product Name : CPP-1X-T

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          September 24, 2024

                          Lead Product(s) : Eflornithine Hydrochloride,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          BePharma
                          Not Confirmed
                          BePharma
                          Not Confirmed

                          Details : SBP-101 (ivospemin) is a small molecule AMD1/ODC1 inhibitor, being evaluated in combination with gemcitabine & nab-paclitaxel for the treatment of metastatic pancreatic ductal adenocarcinoma.

                          Product Name : SBP-101

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          June 24, 2024

                          Lead Product(s) : Ivospemin,Gemcitabine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          BePharma
                          Not Confirmed
                          BePharma
                          Not Confirmed

                          Details : The company intends to use the net proceeds for the clinical development of SBP-101 (ivospemin), which is designed to induce PMI for metastatic pancreatic ductal adenocarcinoma.

                          Product Name : SBP-101

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          January 29, 2024

                          Lead Product(s) : Ivospemin,Gemcitabine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Roth Capital Partners

                          Deal Size : $9.0 million

                          Deal Type : Public Offering

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                          04

                          BePharma
                          Not Confirmed
                          BePharma
                          Not Confirmed

                          Details : The net proceeds will be used for the development of SBP-101 (ivospemin), designed to induce polyamine metabolic inhibition (PMI) for metastatic pancreatic ductal adenocarcinoma.

                          Product Name : SBP-101

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          January 29, 2024

                          Lead Product(s) : Ivospemin,Gemcitabine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Roth Capital Partners

                          Deal Size : $9.0 million

                          Deal Type : Public Offering

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                          05

                          BePharma
                          Not Confirmed
                          BePharma
                          Not Confirmed

                          Details : SBP-101 (ivospemin) is a small molecule AMD1/ODC1 inhibitor currently evaluated in Phase 2/3 in combination with gemcitabine and nab-paclitaxel for metastatic pancreatic ductal adenocarcinoma.

                          Product Name : SBP-101

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          January 25, 2024

                          Lead Product(s) : Ivospemin,Gemcitabine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          blank

                          06

                          BePharma
                          Not Confirmed
                          BePharma
                          Not Confirmed

                          Details : The net proceeds will be used for the development of SBP-101 (ivospemin), designed to induce polyamine metabolic inhibition (PMI) for metastatic pancreatic ductal adenocarcinoma.

                          Product Name : SBP-101

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          January 02, 2024

                          Lead Product(s) : Ivospemin,Gemcitabine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Roth Capital Partners

                          Deal Size : $9.0 million

                          Deal Type : Public Offering

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                          07

                          BePharma
                          Not Confirmed
                          BePharma
                          Not Confirmed

                          Details : CPP-1X-T (eflornithine) is a single agent tablet or high dose powder sachet for several indications including prevention of gastric cancer, treatment of neuroblastoma and recent onset type 1 diabetes. It is approved by USFDA for the treatment of Pediatri...

                          Product Name : CPP-1X-T

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          December 18, 2023

                          Lead Product(s) : Eflornithine Hydrochloride

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : US WorldMeds

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          BePharma
                          Not Confirmed
                          BePharma
                          Not Confirmed

                          Details : CPP-1X-T (eflornithine) is being developed as a single agent tablet or high dose power sachet for several indications including prevention of gastric cancer, treatment of neuroblastoma and recent onset type 1 diabetes.

                          Product Name : CPP-1X-T

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          December 04, 2023

                          Lead Product(s) : Eflornithine Hydrochloride

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase II

                          Sponsor : JDRF

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          BePharma
                          Not Confirmed
                          BePharma
                          Not Confirmed

                          Details : SBP-101 (ivospemin) is a small molecule AMD1/ODC1 inhibitor. It is being evaluated in phase 3 clinical trials in combination with gemcitabine & nab-paclitaxel for the treatment of metastatic pancreatic ductal adenocarcinoma.

                          Product Name : SBP-101

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          November 29, 2023

                          Lead Product(s) : Ivospemin,Gemcitabine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          BePharma
                          Not Confirmed
                          BePharma
                          Not Confirmed

                          Details : Panbela has regained the North American rights to develop and commercialize Flynpovi (the combination of CPP-1X (eflornithine hydrochloride) and sulindac) in patients with FAP. The drug is withdrawn form the european market and company will conduct FAP t...

                          Product Name : CPP-1X-T

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          November 04, 2023

                          Lead Product(s) : Eflornithine Hydrochloride,Sulindac

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Approved FDF

                          Sponsor : One-Two Therapeutics Assets Limited

                          Deal Size : Undisclosed

                          Deal Type : Termination

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