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Find Clinical Drug Pipeline Developments & Deals by Pandion Therapeutics

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details : Pandion's lead candidate, PT101, is an engineered IL-2 mutein fused to a protein backbone designed to selectively activate and expand regulatory T cells (Tregs) for the potential treatment of ulcerative colitis and other autoimmune diseases.

                          Product Name : PT101

                          Product Type : Protein

                          Upfront Cash : $1,850.0 million

                          February 25, 2021

                          Lead Product(s) : PT101

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Sponsor : Merck & Co

                          Deal Size : $1,850.0 million

                          Deal Type : Acquisition

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                          02

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details : The research, done in collaboration with St Vincent’s Institute of Medical Research in Australia and funded by JDRF and the JDRF T1D Fund, showed that PT001 treatment delayed the onset of hyperglycemia in a mouse model of Type 1 diabetes.

                          Product Name : PT001

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          February 22, 2021

                          Lead Product(s) : Glycopyrronium Bromide

                          Therapeutic Area : Immunology

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details : Pandion's lead candidate, PT101, is an engineered IL-2 mutein fused to a protein backbone designed to selectively activate and expand regulatory T cells (Tregs) for the potential treatment of ulcerative colitis and other autoimmune diseases.

                          Product Name : PT101

                          Product Type : Protein

                          Upfront Cash : $1,850.0 million

                          January 04, 2021

                          Lead Product(s) : PT101

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Sponsor : Merck & Co

                          Deal Size : $1,850.0 million

                          Deal Type : Acquisition

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                          04

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details : Pandion utilizes its TALON (Therapeutic Autoimmune reguLatOry proteiN) drug design and discovery platform to create antibody-based candidates that target known control nodes in the immune system.

                          Product Name : PT001

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          October 28, 2020

                          Lead Product(s) : Glycopyrronium Bromide

                          Therapeutic Area : Immunology

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details : Patent protects foundational intellectual property and pioneering work on Pandion’s therapeutic autoimmune regulatory protein (TALON) drug design platform.

                          Product Name : PT101

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          September 06, 2020

                          Lead Product(s) : PT101

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details : Funds will be used in company's lead asset, PT101, a combination of an interleukin-2 mutein effector module with a protein backbone, designed to selectively expand regulatory T cells systemically without activating proinflammatory cells.

                          Product Name : PT101

                          Product Type : Protein

                          Upfront Cash : Undisclosed

                          June 29, 2020

                          Lead Product(s) : PT101

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Sponsor : Undisclosed

                          Deal Size : $75.0 million

                          Deal Type : Public Offering

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                          07

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details : Trial to evaluate safety and tolerability of PT101, as well as expansion of regulatory T cells.

                          Product Name : PT101

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          February 24, 2020

                          Lead Product(s) : PT101

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details : Proceeds to support advancement of pipeline of modular proteins and bifunctional antibodies for autoimmune diseases, including lead clinical-stage IL?2 mutein program.

                          Product Name : PT101

                          Product Type : Protein

                          Upfront Cash : Undisclosed

                          January 04, 2020

                          Lead Product(s) : PT101

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Sponsor : Access Biotechnology

                          Deal Size : $80.0 million

                          Deal Type : Series B Financing

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