Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : PT101
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Merck & Co
Deal Size : $1,850.0 million
Deal Type : Acquisition
Merck to Acquire Pandion Therapeutics
Details : Pandion's lead candidate, PT101, is an engineered IL-2 mutein fused to a protein backbone designed to selectively activate and expand regulatory T cells (Tregs) for the potential treatment of ulcerative colitis and other autoimmune diseases.
Product Name : PT101
Product Type : Protein
Upfront Cash : $1,850.0 million
February 25, 2021
Lead Product(s) : PT101
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Merck & Co
Deal Size : $1,850.0 million
Deal Type : Acquisition
Lead Product(s) : Glycopyrronium Bromide
Therapeutic Area : Immunology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The research, done in collaboration with St Vincent’s Institute of Medical Research in Australia and funded by JDRF and the JDRF T1D Fund, showed that PT001 treatment delayed the onset of hyperglycemia in a mouse model of Type 1 diabetes.
Product Name : PT001
Product Type : Protein
Upfront Cash : Inapplicable
February 22, 2021
Lead Product(s) : Glycopyrronium Bromide
Therapeutic Area : Immunology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : PT101
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Merck & Co
Deal Size : $1,850.0 million
Deal Type : Acquisition
Merck Completes Acquisition of Pandion Therapeutics
Details : Pandion's lead candidate, PT101, is an engineered IL-2 mutein fused to a protein backbone designed to selectively activate and expand regulatory T cells (Tregs) for the potential treatment of ulcerative colitis and other autoimmune diseases.
Product Name : PT101
Product Type : Protein
Upfront Cash : $1,850.0 million
January 04, 2021
Lead Product(s) : PT101
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Merck & Co
Deal Size : $1,850.0 million
Deal Type : Acquisition
Lead Product(s) : Glycopyrronium Bromide
Therapeutic Area : Immunology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Pandion utilizes its TALON (Therapeutic Autoimmune reguLatOry proteiN) drug design and discovery platform to create antibody-based candidates that target known control nodes in the immune system.
Product Name : PT001
Product Type : Protein
Upfront Cash : Inapplicable
October 28, 2020
Lead Product(s) : Glycopyrronium Bromide
Therapeutic Area : Immunology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : PT101
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Patent protects foundational intellectual property and pioneering work on Pandion’s therapeutic autoimmune regulatory protein (TALON) drug design platform.
Product Name : PT101
Product Type : Protein
Upfront Cash : Inapplicable
September 06, 2020
Lead Product(s) : PT101
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : PT101
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : $75.0 million
Deal Type : Public Offering
Pandion Therapeutics Raises $75 million IPO
Details : Funds will be used in company's lead asset, PT101, a combination of an interleukin-2 mutein effector module with a protein backbone, designed to selectively expand regulatory T cells systemically without activating proinflammatory cells.
Product Name : PT101
Product Type : Protein
Upfront Cash : Undisclosed
June 29, 2020
Lead Product(s) : PT101
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : $75.0 million
Deal Type : Public Offering
Lead Product(s) : PT101
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Pandion Announces First Subject Dosed in a Phase 1 Clinical Trial of PT101
Details : Trial to evaluate safety and tolerability of PT101, as well as expansion of regulatory T cells.
Product Name : PT101
Product Type : Protein
Upfront Cash : Inapplicable
February 24, 2020
Lead Product(s) : PT101
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : PT101
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Access Biotechnology
Deal Size : $80.0 million
Deal Type : Series B Financing
Pandion Raises $80 Million Series B to Advance Autoimmune Therapies
Details : Proceeds to support advancement of pipeline of modular proteins and bifunctional antibodies for autoimmune diseases, including lead clinical-stage IL?2 mutein program.
Product Name : PT101
Product Type : Protein
Upfront Cash : Undisclosed
January 04, 2020
Lead Product(s) : PT101
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Access Biotechnology
Deal Size : $80.0 million
Deal Type : Series B Financing