Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : GSK4532990
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Study Phase : Phase II
Sponsor : GSK
Deal Size : Undisclosed
Deal Type : Collaboration
PathAI Announces Collaboration with GSK on NASH Phase 2b Clinical Trial
Details : Under the collaboration, the trial will measure improvements in liver histology with GSK4532990 compared with placebo in participants with NASH and advanced fibrosis.
Brand Name : GSK4532990
Molecule Type : Large molecule
Upfront Cash : Undisclosed
March 30, 2023
Lead Product(s) : GSK4532990
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Highest Development Status : Phase II
Sponsor : GSK
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Resmetirom
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
PathAI To Present Three Abstracts at International Liver Congress 2022
Details : Resmetirom (MGL-3196) is a liver-directed, orally active, selective thyroid hormone receptor-β agonist designed to improve NASH by increasing hepatic fat metabolism and reducing lipotoxicity.
Brand Name : MGL-3196
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 08, 2022
Lead Product(s) : Resmetirom
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Semaglutide
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Study Phase : Phase II
Sponsor : Novo Nordisk
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The results from the study indicated that via both manual and AI assessment, NASH resolution was dose dependent, with a higher proportion of patients receiving semaglutide 0.4mg achieving NASH resolution without fibrosis worsening, compared to patients r...
Brand Name : Undisclosed
Molecule Type : Peptide
Upfront Cash : Not Applicable
November 10, 2021
Lead Product(s) : Semaglutide
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Highest Development Status : Phase II
Sponsor : Novo Nordisk
Deal Size : Not Applicable
Deal Type : Not Applicable
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