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    [{"orgOrder":0,"company":"Rain Oncology","sponsor":"Pathos","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Acquisition","leadProduct":"Milademetan","moa":"MDM2","graph1":"Oncology","graph2":"Phase III","graph3":"Rain Oncology","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Rain Oncology \/ Pathos","highestDevelopmentStatusID":"10","companyTruncated":"Rain Oncology \/ Pathos"},{"orgOrder":0,"company":"Rain Oncology","sponsor":"Guggenheim Securities","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Public Offering","leadProduct":"Milademetan","moa":"MDM2","graph1":"Oncology","graph2":"Phase III","graph3":"Rain Oncology","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Rain Oncology \/ Guggenheim Securities","highestDevelopmentStatusID":"10","companyTruncated":"Rain Oncology \/ Guggenheim Securities"},{"orgOrder":0,"company":"Rain Oncology","sponsor":"Boxer Capital","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Series B Financing","leadProduct":"Milademetan","moa":"MDM2","graph1":"Oncology","graph2":"Phase III","graph3":"Rain Oncology","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Rain Oncology \/ Boxer Capital","highestDevelopmentStatusID":"10","companyTruncated":"Rain Oncology \/ Boxer Capital"},{"orgOrder":0,"company":"Pathos","sponsor":"New Enterprise Associates","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Series C Financing","leadProduct":"P-500","moa":"PRMT5","graph1":"Oncology","graph2":"Phase I","graph3":"Pathos","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Pathos \/ New Enterprise Associates","highestDevelopmentStatusID":"6","companyTruncated":"Pathos \/ New Enterprise Associates"},{"orgOrder":0,"company":"Rain Oncology","sponsor":"Pathos","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Acquisition","leadProduct":"Milademetan","moa":"MDM2","graph1":"Oncology","graph2":"Phase III","graph3":"Rain Oncology","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Rain Oncology \/ Pathos","highestDevelopmentStatusID":"10","companyTruncated":"Rain Oncology \/ Pathos"},{"orgOrder":0,"company":"Rain Oncology","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Milademetan","moa":"MDM2","graph1":"Oncology","graph2":"Phase III","graph3":"Rain Oncology","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Rain Oncology \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Rain Oncology \/ Inapplicable"},{"orgOrder":0,"company":"Rain Oncology","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Milademetan","moa":"MDM2","graph1":"Oncology","graph2":"Phase III","graph3":"Rain Oncology","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Rain Oncology \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Rain Oncology \/ Inapplicable"},{"orgOrder":0,"company":"Rain Oncology","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Milademetan","moa":"MDM2","graph1":"Oncology","graph2":"Phase III","graph3":"Rain Oncology","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Rain Oncology \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Rain Oncology \/ Inapplicable"},{"orgOrder":0,"company":"Rain Oncology","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Milademetan","moa":"MDM2","graph1":"Oncology","graph2":"Phase II","graph3":"Rain Oncology","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Rain Oncology \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Rain Oncology \/ Inapplicable"},{"orgOrder":0,"company":"Rain Oncology","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Milademetan","moa":"MDM2","graph1":"Oncology","graph2":"Phase II","graph3":"Rain Oncology","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Rain Oncology \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Rain Oncology \/ Inapplicable"},{"orgOrder":0,"company":"Rain Oncology","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Milademetan","moa":"MDM2","graph1":"Oncology","graph2":"Phase II","graph3":"Rain Oncology","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Rain Oncology \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Rain Oncology \/ Inapplicable"},{"orgOrder":0,"company":"Rain Oncology","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Milademetan","moa":"MDM2","graph1":"Oncology","graph2":"Phase II","graph3":"Rain Oncology","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Rain Oncology \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Rain Oncology \/ Inapplicable"},{"orgOrder":0,"company":"Rain Oncology","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Milademetan","moa":"MDM2","graph1":"Oncology","graph2":"Phase III","graph3":"Rain Oncology","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Rain Oncology \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Rain Oncology \/ Inapplicable"},{"orgOrder":0,"company":"Rain Oncology","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Milademetan","moa":"MDM2","graph1":"Oncology","graph2":"Phase II","graph3":"Rain Oncology","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Rain Oncology \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Rain Oncology \/ Inapplicable"},{"orgOrder":0,"company":"Rain Oncology","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Milademetan","moa":"MDM2","graph1":"Oncology","graph2":"Phase III","graph3":"Rain Oncology","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Rain Oncology \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Rain Oncology \/ Inapplicable"},{"orgOrder":0,"company":"Rain Oncology","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Milademetan","moa":"MDM2","graph1":"Oncology","graph2":"Phase III","graph3":"Rain Oncology","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Rain Oncology \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Rain Oncology \/ Inapplicable"},{"orgOrder":0,"company":"Rain Oncology","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Milademetan","moa":"MDM2","graph1":"Oncology","graph2":"Phase III","graph3":"Rain Oncology","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Rain Oncology \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Rain Oncology \/ Inapplicable"},{"orgOrder":0,"company":"Rain Oncology","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Milademetan","moa":"MDM2","graph1":"Oncology","graph2":"Phase II","graph3":"Rain Oncology","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Rain Oncology \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Rain Oncology \/ Inapplicable"},{"orgOrder":0,"company":"Rain Oncology","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Milademetan","moa":"MDM2","graph1":"Oncology","graph2":"Phase II","graph3":"Rain Oncology","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Rain Oncology \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Rain Oncology \/ Inapplicable"},{"orgOrder":0,"company":"Pathos","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Pocenbrodib","moa":"||CBP\/p300","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Pathos","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Pathos \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Pathos \/ Inapplicable"}]

    Find Clinical Drug Pipeline Developments & Deals by Pathos

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                            01

                            Pathos

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                            Peptide Therapy Summit
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                            Pathos

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                            Lead Product(s) : Pocenbrodib,Abiraterone Acetate

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Pathos AI Doses First Patient in Phase 1b/2a Pocenbrodib CBP/p300 Trial

                            Details : FT-7051 (pocenbrodib) is a CBP/p300 inhibitor, is being investigated as alone and in combination with abiraterone acetate, in patients with mCRPC.

                            Product Name : FT-7051

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            March 20, 2025

                            Lead Product(s) : Pocenbrodib,Abiraterone Acetate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Pathos

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                            Peptide Therapy Summit
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                            Pathos

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                            Peptide Therapy Summit
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                            Lead Product(s) : P-500

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : New Enterprise Associates

                            Deal Size : $62.0 million

                            Deal Type : Series C Financing

                            DEALS_DEV arrow-down

                            Pathos AI Closes $62M Round to Advance Drug Development Platform

                            Details : The financing aims to fund the clinical development of the company's lead product P-500, which is being evaluated for treating advanced solid tumors.

                            Product Name : P-500

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            October 29, 2024

                            Lead Product(s) : P-500

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : New Enterprise Associates

                            Deal Size : $62.0 million

                            Deal Type : Series C Financing

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                            03

                            Rain Oncology

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                            Rain Oncology

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                            Lead Product(s) : Milademetan

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Pathos

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Pathos AI Completes Acquisition of Rain Oncology

                            Details : Through the acquisition of Rain Oncology, Pathos gains access to its product canditate RAIN-32 (milademetan), a small molecule, oral inhibitor of the p53-MDM2 complex that reactivates p53.

                            Product Name : RAIN-32

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            January 26, 2024

                            Lead Product(s) : Milademetan

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Pathos

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            04

                            Rain Oncology

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                            Rain Oncology

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                            Lead Product(s) : Milademetan

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Pathos

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Rain Oncology Enters into Agreement to be Acquired by Pathos AI for $1.16 in Cash per Share Plus Contingent Va...

                            Details : Through the acquisition of Rain Oncology, Pathos gains access to its product canditate RAIN-32 (milademetan), a small molecule, oral inhibitor of the p53-MDM2 complex that reactivates p53.

                            Product Name : RAIN-32

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            December 13, 2023

                            Lead Product(s) : Milademetan

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Pathos

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            05

                            Rain Oncology

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                            Rain Oncology

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                            Lead Product(s) : Milademetan

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Rain Oncology Provides Company Update and Outlines Strategic Priorities of Milademetan Clinical Programs

                            Details : RAIN-32 (milademetan) is an oral small molecule inhibitor of the p53-MDM2 complex that reactivates p53. It has demonstrated antitumor activity in an MDM2- amplified subtype of liposarcoma (LPS) and other solid tumors.

                            Product Name : RAIN-32

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 30, 2023

                            Lead Product(s) : Milademetan

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Rain Oncology

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                            Rain Oncology

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                            Lead Product(s) : Milademetan

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Rain Oncology Announces Topline Results from Phase 3 MANTRA Trial of Milademetan for the Treatment of Dediffer...

                            Details : RAIN-32 (milademetan) is an oral small molecule inhibitor of the p53-MDM2 complex that reactivates p53. Milademetan has demonstrated antitumor activity in an MDM2- amplified subtype of liposarcoma (LPS) and other solid tumors.

                            Product Name : RAIN-32

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 22, 2023

                            Lead Product(s) : Milademetan

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Rain Oncology

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                            Rain Oncology

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                            Lead Product(s) : Milademetan

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Phase 1 Clinical Data of Milademetan Published in Journal of Clinical Oncology

                            Details : RAIN-32 (milademetan) is an oral small molecule inhibitor of the p53-MDM2 complex that reactivates p53. Milademetan has demonstrated antitumor activity in an MDM2- amplified subtype of liposarcoma (LPS) and other solid tumors.

                            Product Name : RAIN-32

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            January 23, 2023

                            Lead Product(s) : Milademetan

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Rain Oncology

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                            Rain Oncology

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                            Lead Product(s) : Milademetan

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Rain Therapeutics Announces a Poster Presentation at the 2022 San Antonio Breast Cancer Symposium

                            Details : Rain’s lead product, milademetan, is a small molecule, oral inhibitor of MDM2-p53 complex that reactivates p53. In addition to milademetan, Rain is also developing a preclinical program that is focused on inducing synthetic lethality in cancer cells by...

                            Product Name : RAIN-32

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            November 23, 2022

                            Lead Product(s) : Milademetan

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Rain Oncology

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                            Rain Oncology

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                            Lead Product(s) : Milademetan

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Rain Therapeutics Announces an Oral Presentation at the Connective Tissue Oncology Society Annual Meeting

                            Details : Rain’s lead product candidate, RAIN-32 (milademetan), an oral small molecule, inhibitor of mouse double minute 2 (MDM2) is being developed in patients with wildtype tumor protein 53 (p53) cancers that are also exhibiting MDM2 dependence.

                            Product Name : RAIN-32

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            November 17, 2022

                            Lead Product(s) : Milademetan

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Rain Oncology

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                            Rain Oncology

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                            Lead Product(s) : Milademetan

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Rain Therapeutics Announces a Poster Presentation at the 34th EORTC/AACR/NCI Symposium

                            Details : Rain-32 (Milademetan), an oral small molecule, inhibitor of mouse double minute 2 is being developed in patients with wildtype tumor protein 53 (p53) cancers that are also exhibiting MDM2 dependence.

                            Product Name : RAIN-32

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            October 26, 2022

                            Lead Product(s) : Milademetan

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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