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    [{"orgOrder":0,"company":"IGAN Biosciences","sponsor":"Selecta Biosciences","pharmaFlowCategory":"D","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Enzyme","year":"2020","type":"Licensing Agreement","leadProduct":"Pegadricase","moa":"||Undisclosed","graph1":"Nephrology","graph2":"Preclinical","graph3":"IGAN Biosciences","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"IGAN Biosciences \/ Selecta Biosciences","highestDevelopmentStatusID":"4","companyTruncated":"IGAN Biosciences \/ Selecta Biosciences"},{"orgOrder":0,"company":"3S Bio Inc","sponsor":"Selecta Biosciences","pharmaFlowCategory":"D","therapeuticArea":"Rheumatology","country":"CHINA","productType":"Enzyme","year":"2020","type":"Licensing Agreement","leadProduct":"Pegadricase","moa":"Undisclosed","graph1":"Rheumatology","graph2":"Phase III","graph3":"3S Bio 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Biosciences","sponsor":"Swedish Orphan Biovitrum AB","pharmaFlowCategory":"D","therapeuticArea":"Rheumatology","country":"U.S.A","productType":"Enzyme","year":"2023","type":"Licensing Agreement","leadProduct":"Pegadricase","moa":"||Undisclosed","graph1":"Rheumatology","graph2":"Phase III","graph3":"Selecta Biosciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Rheumatology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Selecta Biosciences \/ Swedish Orphan Biovitrum AB","highestDevelopmentStatusID":"10","companyTruncated":"Selecta Biosciences \/ Swedish Orphan Biovitrum AB"},{"orgOrder":0,"company":"Selecta Biosciences","sponsor":"Swedish Orphan Biovitrum AB","pharmaFlowCategory":"DU","therapeuticArea":"Rheumatology","country":"U.S.A","productType":"Enzyme","year":"2020","type":"Inapplicable","leadProduct":"Pegadricase","moa":"Undisclosed","graph1":"Rheumatology","graph2":"Phase III","graph3":"Selecta Biosciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Rheumatology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Selecta Biosciences \/ Swedish Orphan Biovitrum AB","highestDevelopmentStatusID":"10","companyTruncated":"Selecta Biosciences \/ Swedish Orphan Biovitrum AB"}]

    Find Clinical Drug Pipeline Developments & Deals for Pegadricase

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                            01

                            Selecta Biosciences

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                            Selecta Biosciences

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                            Lead Product(s) : Pegadricase,ImmTOR

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase III

                            Sponsor : Swedish Orphan Biovitrum AB

                            Deal Size : $705.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Selecta Announces Transition of Manufacturing and Clinical Operations of ImmTOR for SEL-212 to Commercializati...

                            Details : Sobi will transition the manufacturing and development rights of ImmTOR for SEL-212 to Sobi. SEL-212, a combination of Selecta’s ImmTOR immune tolerance platform and a therapeutic uricase enzyme (pegadricase), is in development for chronic refractory g...

                            Product Name : SEL-212

                            Product Type : Enzyme

                            Upfront Cash : $75.0 million

                            October 31, 2023

                            Lead Product(s) : Pegadricase,ImmTOR

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase III

                            Sponsor : Swedish Orphan Biovitrum AB

                            Deal Size : $705.0 million

                            Deal Type : Licensing Agreement

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                            02

                            Selecta Biosciences

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                            Selecta Biosciences

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                            Lead Product(s) : Pegadricase,SEL-110

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Phase 3 DISSOLVE Program of SEL-212 in Chronic Refractory Gout Meets Primary Endpoint

                            Details : SEL-212 (combination of ImmTOR immune tolerance platform and pegadricase) is designed to reduce serum urate levels in people with chronic refractory gout, potentially reducing harmful tissue urate deposits which causes debilitating gout flares and joint ...

                            Product Name : SEL-212

                            Product Type : Enzyme

                            Upfront Cash : Inapplicable

                            March 21, 2023

                            Lead Product(s) : Pegadricase,SEL-110

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            3S Bio Inc

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                            3S Bio Inc

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                            Lead Product(s) : Pegadricase

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase III

                            Sponsor : Selecta Biosciences

                            Deal Size : $4.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            3SBio Inc. Received Milestone Payment of USD 4 Million Upon Commencement of Phase III Clinical Program of SEL-...

                            Details : Selecta Biosciences, 3SBio partner, has commenced the phase III clinical program of a combination therapy involving SEL-212 for the treatment of chronic refractory gout on behalf of SobiTM, and has made a milestone payment of USD 4 million to 3SBio.

                            Product Name : SEL-212

                            Product Type : Enzyme

                            Upfront Cash : Undisclosed

                            November 23, 2020

                            Lead Product(s) : Pegadricase

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase III

                            Sponsor : Selecta Biosciences

                            Deal Size : $4.0 million

                            Deal Type : Licensing Agreement

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                            04

                            Selecta Biosciences

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                            Lead Product(s) : Pegadricase

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase II

                            Sponsor : Swedish Orphan Biovitrum AB

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Sobi and Selecta Announce Strategic Licensing Agreement for SEL-212, a Phase 3-ready Novel Treatment for Chron...

                            Details : This strategic licensing agreement is for SEL-212, a combination of Selecta's tolerogenic ImmTOR immune tolerance platform and a therapeutic uricase enzyme (pegadricase) for the treatment of chronic refractory gout.

                            Product Name : SEL-212

                            Product Type : Enzyme

                            Upfront Cash : Undisclosed

                            November 06, 2020

                            Lead Product(s) : Pegadricase

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase II

                            Sponsor : Swedish Orphan Biovitrum AB

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            05

                            Selecta Biosciences

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                            Selecta Biosciences

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                            Lead Product(s) : Pegadricase

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase III

                            Sponsor : Swedish Orphan Biovitrum AB

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sobi and Selecta Biosciences Announce Topline Data of SEL-212 From the Phase 2 COMPARE Study

                            Details : Patients with tophi showed a substantially higher overall response rate for SEL-212 versus pegloticase and a statistically significant overall reduction in mean SUA levels for SEL-212 versus pegloticase.

                            Product Name : SEL-212

                            Product Type : Enzyme

                            Upfront Cash : Inapplicable

                            September 30, 2020

                            Lead Product(s) : Pegadricase

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase III

                            Sponsor : Swedish Orphan Biovitrum AB

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Swedish Orphan Biovitrum AB

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                            AACR Annual meeting
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                            Swedish Orphan Biovitrum AB

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                            Not Confirmed
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                            Lead Product(s) : Pegadricase

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase III

                            Sponsor : Selecta Biosciences

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            First Patient Randomized in Sobi's Phase 3 DISSOLVE Clinical Program of SEL-212 for Chronic Refractory Gout

                            Details : The phase 3 DISSOLVE clinical programme a randomized double-blind, placebo-controlled study in which SEL-212 will be evaluated at two doses of ImmTOR, and one dose of pegadricase in both studies.

                            Product Name : SEL-212

                            Product Type : Enzyme

                            Upfront Cash : Inapplicable

                            September 23, 2020

                            Lead Product(s) : Pegadricase

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase III

                            Sponsor : Selecta Biosciences

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            IGAN Biosciences

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                            IGAN Biosciences

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                            Lead Product(s) : Pegadricase,Undisclosed

                            Therapeutic Area : Nephrology

                            Study Phase : Preclinical

                            Sponsor : Selecta Biosciences

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Selecta Biosciences and IGAN Biosciences Collaborate to Study ImmTOR™ Immune Tolerance Platform in Combinati...

                            Details : The companies have entered into a Research License and Option agreement to study Selecta’s ImmTOR™ immune tolerance platform in combination with IGAN’s immunoglobulin A (IgA) protease for the treatment of IgA Nephropathy (IgAN).

                            Product Name : SEL-212

                            Product Type : Enzyme

                            Upfront Cash : Undisclosed

                            August 10, 2020

                            Lead Product(s) : Pegadricase,Undisclosed

                            Therapeutic Area : Nephrology

                            Highest Development Status : Preclinical

                            Sponsor : Selecta Biosciences

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            08

                            Selecta Biosciences

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                            Lead Product(s) : Pegadricase

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase II

                            Sponsor : Swedish Orphan Biovitrum AB

                            Deal Size : $100.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Sobi And Selecta Announce Closing of Previously Announced Strategic Licensing Agreement For Sel-212

                            Details : The licensing agreement includes the global rights, excluding China, for the product SEL-212. SEL-212 is a combination of Selecta's tolerogenic ImmTOR immune tolerance platform and a therapeutic uricase enzyme that is designed for the treatment of chroni...

                            Product Name : SEL-212

                            Product Type : Enzyme

                            Upfront Cash : $100.0 million

                            July 28, 2020

                            Lead Product(s) : Pegadricase

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase II

                            Sponsor : Swedish Orphan Biovitrum AB

                            Deal Size : $100.0 million

                            Deal Type : Licensing Agreement

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