Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Study Phase : Phase I
Sponsor : H.C. Wainwright & Co.
Deal Size : $10.0 million
Deal Type : Private Placement
Details : BioLexa (gentamicin) is a patented, proprietary antimicrobial topical formulation being developed for treatment of diseases mediated by Staphylococcal biofilms. Bacterial biofilms are specialized communities consisting of bacteria adhered to a surface an...
Product Name : BioLexa
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
March 01, 2023
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Highest Development Status : Phase I
Sponsor : H.C. Wainwright & Co.
Deal Size : $10.0 million
Deal Type : Private Placement
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Study Phase : Phase I
Sponsor : H.C. Wainwright & Co.
Deal Size : $10.0 million
Deal Type : Private Placement
Hoth Therapeutics Announces $10 Million Private Placement Priced At-the-Market Under Nasdaq Rules
Details : BioLexa (gentamicin) is a patented, proprietary antimicrobial topical formulation being developed for treatment of diseases mediated by Staphylococcal biofilms. The BioLexa formulation is optimized to prevent Staphylococcal biofilm formation.
Product Name : BioLexa
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
December 29, 2022
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Highest Development Status : Phase I
Sponsor : H.C. Wainwright & Co.
Deal Size : $10.0 million
Deal Type : Private Placement
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Study Phase : Phase I
Sponsor : Novotech
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Receiving clearance for Cohort 2 is the next critical milestone in the Phase 1b clinical trial in Australia. Hoth's atopic dermatitis solution, BioLexa, represents a significant global opportunity and looks forward to advancing the treatment through the ...
Product Name : BioLexa
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 10, 2021
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Highest Development Status : Phase I
Sponsor : Novotech
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Study Phase : Phase I
Sponsor : Novotech
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : BioLexa is patented, proprietary antimicrobial topical formulation against diseases mediated by Staphylococcal biofilms. BioLexa formulation is optimized to prevent Staphylococcal biofilm formation, keeping bacteria in more susceptible state to antimicro...
Product Name : BioLexa
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
September 21, 2021
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Highest Development Status : Phase I
Sponsor : Novotech
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Study Phase : Phase I
Sponsor : H.C. Wainwright & Co.
Deal Size : $15.0 million
Deal Type : Private Placement
Hoth Therapeutics Announces $15 Million Private Placement Priced At-the-Market Under Nasdaq Rules
Details : The Company currently intends to use the net proceeds from the private placement for further development of Hoth's product candidates including lead drug BioLexa and for working capital and general corporate purposes.
Product Name : BioLexa
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
August 03, 2021
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Highest Development Status : Phase I
Sponsor : H.C. Wainwright & Co.
Deal Size : $15.0 million
Deal Type : Private Placement
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Study Phase : Phase I
Sponsor : Novotech
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The first in human clinical trial is randomized, double-blind, vehicle controlled study to determine the safety, tolerability, PK and efficacy of twice daily application of topical BioLexa™ lotion, in adult and adolescent patients with mild to moderate...
Product Name : BioLexa
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 22, 2021
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Highest Development Status : Phase I
Sponsor : Novotech
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Study Phase : Phase I
Sponsor : Novotech
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Hoth Therapeutics has completed recruitment of Cohort 1 for its upcoming first in human clinical trial of the proprietary BioLexa platform to treat atopic dermatitis, also known as eczema.
Product Name : BioLexa
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 03, 2021
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Highest Development Status : Phase I
Sponsor : Novotech
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Study Phase : Phase I
Sponsor : Novotech
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Following the successful completion of the Phase 1b trial, the Company intends to conduct a Phase 2 trial with adult and adolescent patients to continue clinical investigation of the efficacy of BioLexa Lotion for treatment of mild to moderate atopic der...
Product Name : BioLexa
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 12, 2020
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Highest Development Status : Phase I
Sponsor : Novotech
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Study to determine the safety, tolerability, pharmacokinetics and efficacy of twice daily application of topical BioLexa in healthy subjects and patients with mild to moderate atopic dermatitis.
Product Name : BioLexa
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
August 13, 2020
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable