Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Discovery Platform
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : $2,890.0 million
Deal Type : Expanded Collaboration
PeptiDream Announces Expansion of Peptide Discovery Collaboration with Novartis
Details : PeptiDream will use its peptide discovery platform to identify and optimize novel macrocyclic peptides against targets selected by Novartis, potentially for radionuclide conjugation.
Brand Name : Undisclosed
Molecule Type : Peptide
Upfront Cash : $180.0 million
April 30, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Discovery Platform
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : $2,890.0 million
Deal Type : Expanded Collaboration
Lead Product(s) : Peptide-radioisotope Drug Conjugate
Therapeutic Area : Technology
Study Phase : Discovery
Sponsor : Genentech
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Under the collaboration, PeptiDream will use its proprietary Peptide Discovery Platform System (“PDPS”) technology to discover, optimize, and develop macrocyclic peptide candidates for use as peptide-RI drug conjugates against targets of interest to ...
Brand Name : Undisclosed
Molecule Type : Peptide
Upfront Cash : Undisclosed
September 19, 2023
Lead Product(s) : Peptide-radioisotope Drug Conjugate
Therapeutic Area : Technology
Highest Development Status : Discovery
Sponsor : Genentech
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Protein Degrader Drug
Therapeutic Area : Technology
Study Phase : Discovery
Sponsor : Astellas Pharma
Deal Size : $749.9 million
Deal Type : Collaboration
Details : The collaboration aims to discover novel protein degraders by leveraging PeptiDream's PDPS (Peptide Discovery Platform System) technology, for two targets and Astellas will have the option to select up to three additional targets to be included in the co...
Brand Name : Undisclosed
Molecule Type : Peptide
Upfront Cash : $21.2 million
July 25, 2023
Lead Product(s) : Protein Degrader Drug
Therapeutic Area : Technology
Highest Development Status : Discovery
Sponsor : Astellas Pharma
Deal Size : $749.9 million
Deal Type : Collaboration
Lead Product(s) : AZP-3813
Therapeutic Area : Endocrinology
Study Phase : Phase I
Recipient : Amolyt Pharma
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : AZP-3813, a peptide GHR antagonist, is being developed as a potential treatment for acromegaly to be used in combination with somatostatin analogues (SSAs) for patients who do not adequately respond to SSAs alone.
Brand Name : AZP-3813
Molecule Type : Peptide
Upfront Cash : Not Applicable
June 05, 2023
Lead Product(s) : AZP-3813
Therapeutic Area : Endocrinology
Highest Development Status : Phase I
Recipient : Amolyt Pharma
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Candidate was discovered using PeptiDream’s proprietary Peptide Discovery Platform System (PDPS) and demonstrated potent and selective GPC3 binding, rapid cellular internalization and sustained tumor specific uptake and anti-tumor efficacy in pre-clini...
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 22, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Peptide-drug Conjugate
Therapeutic Area : Technology
Study Phase : Discovery Platform
Sponsor : MSD Pharmaceuticals
Deal Size : $2,100.0 million
Deal Type : Collaboration
Details : Under the agreement, PeptiDream will provide peptide candidates identified from PeptiDream’s proprietary Peptide Discovery Platform System (“PDPS”) technology for use as PDCs against targets of interest to MSD.
Brand Name : Undisclosed
Molecule Type : Peptide
Upfront Cash : Undisclosed
December 27, 2022
Lead Product(s) : Peptide-drug Conjugate
Therapeutic Area : Technology
Highest Development Status : Discovery Platform
Sponsor : MSD Pharmaceuticals
Deal Size : $2,100.0 million
Deal Type : Collaboration
Lead Product(s) : Peptide-drug Conjugate
Therapeutic Area : Technology
Study Phase : Discovery Platform
Sponsor : Eli Lilly
Deal Size : $1,235.0 million
Deal Type : Collaboration
Details : Under the agreement, PeptiDream will utilize its proprietary Peptide Discovery Platform System (“PDPS”) technology to identify high affinity macrocyclic peptide ligands to Lilly-elected targets of interest for the discovery and development of novel p...
Brand Name : Undisclosed
Molecule Type : Peptide
Upfront Cash : Undisclosed
December 26, 2022
Lead Product(s) : Peptide-drug Conjugate
Therapeutic Area : Technology
Highest Development Status : Discovery Platform
Sponsor : Eli Lilly
Deal Size : $1,235.0 million
Deal Type : Collaboration
PeptiDream and RayzeBio Expand Alliance on Peptide-Radiotherapeutics
Details : Extension of the research collaboration term to allow for additional peptide-RI conjugate discovery and development programs. RayzeBio grants PeptiDream an option to attain development and commercialization rights in Japan to the joint peptide-RI program...
Brand Name : Undisclosed
Molecule Type : Peptide
Upfront Cash : Undisclosed
August 09, 2022
Lead Product(s) : Peptide-drug Conjugates
Therapeutic Area : Neurology
Study Phase : Discovery
Sponsor : Takeda Pharmaceutical
Deal Size : $3,500.0 million
Deal Type : Expanded Collaboration
Details : The new collaboration expands the use of the TfR1 binding peptide ligands for CNS targets associated with neurodegeneration allowing Takeda to conjugate the peptides with therapeutic cargoes optimized to cross the blood-brain barrier (BBB).
Brand Name : Undisclosed
Molecule Type : Peptide
Upfront Cash : Undisclosed
July 29, 2021
Lead Product(s) : Peptide-drug Conjugates
Therapeutic Area : Neurology
Highest Development Status : Discovery
Sponsor : Takeda Pharmaceutical
Deal Size : $3,500.0 million
Deal Type : Expanded Collaboration
Lead Product(s) : Peptide-siRNA Conjugates
Therapeutic Area : Genetic Disease
Study Phase : Discovery Platform
Sponsor : Alnylam Pharmaceuticals
Deal Size : $2,200.0 million
Deal Type : Collaboration
Alnylam and PeptiDream Enter into Collaboration Agreement
Details : PeptiDream will select, optimize, and synthesize peptides for each receptor. Alnylam will then generate peptide-siRNA conjugates and perform in vitro and in vivo studies to support final peptide selection.
Brand Name : Undisclosed
Molecule Type : Peptide
Upfront Cash : Undisclosed
July 29, 2021
Lead Product(s) : Peptide-siRNA Conjugates
Therapeutic Area : Genetic Disease
Highest Development Status : Discovery Platform
Sponsor : Alnylam Pharmaceuticals
Deal Size : $2,200.0 million
Deal Type : Collaboration
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