Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : PLG0206
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : PLG0206 is an investigational broad-spectrum, anti-bacterial and anti-biofilm peptide therapeutic currently in clinical development for the treatment of Periprosthetic Joint Infection.
Brand Name : PLG0206
Molecule Type : Peptide
Upfront Cash : Not Applicable
May 24, 2023
Lead Product(s) : PLG0206
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : PLG0206
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : PLG0206 is an investigational, broad-spectrum, anti-biofilm, anti-infective peptide, best-in-class, rapid bactericidal therapeutic currently in clinical development for the treatment of periprosthetic joint infection (PJI).
Brand Name : PLG0206
Molecule Type : Peptide
Upfront Cash : Not Applicable
April 06, 2023
Lead Product(s) : PLG0206
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : PLG0206
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Results demonstrate that PLG0206 was active against all tested isolates and retained activity against multi-drug resistant (MDR) strains, suggesting that the unique mechanism of action of PLG0206 can overcome the drug-resistance mechanisms found in these...
Brand Name : PLG0206
Molecule Type : Peptide
Upfront Cash : Not Applicable
October 07, 2022
Lead Product(s) : PLG0206
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : PLG0206
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : PLG0206 is an investigational, broad-spectrum, non-traditional antibiotic peptide therapeutic for the treatment of PJI. PLG0206 has the potential to rapidly target bacteria and persistent pathogens that produce biofilm and evade conventional antibiotics.
Brand Name : PLG0206
Molecule Type : Peptide
Upfront Cash : Not Applicable
October 06, 2022
Lead Product(s) : PLG0206
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : PLG0206
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : PLG0206 was designed with a unique mechanism of action that allows it to directly address persistent bacterial pathogens within the biofilm that evade standard-of-care antibiotics by targeting and disrupting bacterial membranes to trigger bacterial cell ...
Brand Name : PLG0206
Molecule Type : Peptide
Upfront Cash : Not Applicable
July 19, 2022
Lead Product(s) : PLG0206
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Discovery Platform
Recipient : Orion Biotechnology
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Peptilogics’ Nautilus™ platform enables in silico predictive peptide design across diverse targets to efficiently access new functional chemical space and custom design therapeutics.
Brand Name : Undisclosed
Molecule Type : Peptide
Upfront Cash : Undisclosed
July 12, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Discovery Platform
Recipient : Orion Biotechnology
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : PLG0206
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Poster and oral presentation of PLG0206 showcase broad-spectrum activity against drug-resistant bacteria and its ability to prevent spontaneous mutant growth with a variety of pathogens that cause periprosthetic joint infections (PJI).
Brand Name : PLG0206
Molecule Type : Peptide
Upfront Cash : Not Applicable
April 19, 2022
Lead Product(s) : PLG0206
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : PLG0206
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : PLG0206, is a novel peptide therapy granted orphan drug designation, initially targeted for prosthetic joint infections, an orthopedics indication is best-in-class, broad-spectrum potency targets multi-drug-resistant bacteria with improved resistance pro...
Brand Name : PLG0206
Molecule Type : Peptide
Upfront Cash : Not Applicable
March 22, 2022
Lead Product(s) : PLG0206
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : PLG0301
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Cystic Fibrosis Foundation
Deal Size : Undisclosed
Deal Type : Funding
Details : The award provided by the Cystic Fibrosis Foundation will generate both in vitro and in vivo data about PLG0301 and PLG0206, which may potentially support an Investigational New Drug (IND) application with the FDA for its continued development.
Brand Name : PLG0301
Molecule Type : Peptide
Upfront Cash : Undisclosed
January 05, 2022
Lead Product(s) : PLG0301
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Cystic Fibrosis Foundation
Deal Size : Undisclosed
Deal Type : Funding
Lead Product(s) : PLG0206
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Presight Capital
Deal Size : $35.4 million
Deal Type : Series B Financing
Details : The proceeds of the financing will be used to expand Peptilogics’ computational platform and invest in technologies to improve its drug design engine, as well as accelerate development of a pipeline of peptide therapeutics including the Company’s lea...
Brand Name : PLG0206
Molecule Type : Peptide
Upfront Cash : Undisclosed
December 21, 2020
Lead Product(s) : PLG0206
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Presight Capital
Deal Size : $35.4 million
Deal Type : Series B Financing
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