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                            01

                            Phanes Therapeutics

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                            Lead Product(s) : PT217

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Phanes Therapeutics' PT217 Granted Fast Track Designation by the FDA for NEPC

                            Details : PT217 is a first-in-class native IgG-like bispecific antibody (bsAb) targeting DLL3 and CD4. It is being evaluated for the treatment of patients with neuroendocrine prostate carcinoma.

                            Product Name : Undisclosed

                            Product Type : Large molecule

                            Upfront Cash : Not Applicable

                            December 04, 2024

                            Lead Product(s) : PT217

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

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                            Lead Product(s) : PT-886,Pembrolizumab,Oxaliplatin

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Phanes Therapeutics Doses First Patient in PT886 Study Combined with Chemotherapy

                            Details : PT-886 is a first-in-class native IgG-like bispecific antibody targeting claudin 18.2 & CD47, is being developed for the treatment of gastric, gastroesophageal junction and pancreatic adenocarcinomas.

                            Product Name : PT-886

                            Product Type : Large molecule

                            Upfront Cash : Not Applicable

                            September 09, 2024

                            Lead Product(s) : PT-886,Pembrolizumab,Oxaliplatin

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

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                            Lead Product(s) : PT217

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Phanes Therapeutics’ PT217 Receives Orphan Drug Designation for Neuroendocrine Carcinoma

                            Details : PT217 is a first-in-class native IgG-like bispecific antibody (bsAb) targeting DLL3 and CD4. It is being evaluated for the treatment of patients with neuroendocrine carcinoma.

                            Product Name : PT217

                            Product Type : Large molecule

                            Upfront Cash : Not Applicable

                            August 16, 2024

                            Lead Product(s) : PT217

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Phanes Therapeutics

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                            SCOPE Summit
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                            Lead Product(s) : PT217,Atezolizumab

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : F. Hoffmann-La Roche

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Phanes Partners with Roche To Evaluate PT217 with Anti-PD-L1 Therapy

                            Details : The agreement aims to study PT217, a bispecific antibody targeting DLL3 and CD47, in combo with Roche's atezolizumab for SCLC and neuroendocrine carcinomas.

                            Product Name : PT217

                            Product Type : Large molecule

                            Upfront Cash : Undisclosed

                            May 08, 2024

                            Lead Product(s) : PT217,Atezolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : F. Hoffmann-La Roche

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            05

                            Phanes Therapeutics

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                            Lead Product(s) : PT217

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Phanes Therapeutics' PT217 granted Fast Track Designation by the FDA

                            Details : PT217 is a first-in-class native IgG-like bispecific antibody (bsAb) targeting DLL3 and CD4. It is being evaluated for the treatment of patients with extensive-stage small cell lung cancer.

                            Product Name : PT217

                            Product Type : Large molecule

                            Upfront Cash : Not Applicable

                            April 08, 2024

                            Lead Product(s) : PT217

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

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                            Lead Product(s) : PT-886,Pembrolizumab,Pemetrexed

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Phanes Therapeutics’ PT886 Receives Fast Track Designation for Pancreatic Cancer

                            Details : PT886 is a first-in-class bispecific antibody targeting claudin 18.2 and CD47, being developed for gastric, gastroesophageal junction, and pancreatic adenocarcinomas.

                            Product Name : PT-886

                            Product Type : Large molecule

                            Upfront Cash : Not Applicable

                            March 20, 2024

                            Lead Product(s) : PT-886,Pembrolizumab,Pemetrexed

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Phanes Therapeutics

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                            Lead Product(s) : PT886,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Merck & Co

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Phanes Therapeutics, Inc. Announces Clinical Trial Collaboration and Supply Agreement with Merck to Evaluate P...

                            Details : The collaboration aims to study PT886, a first-in-class bispecific antibody targeting claudin 18.2 and CD47, in combination with Merck's anti-PD-1 therapy, Keytruda (pembrolizumab), in patients with claudin 18.2 positive gastric or gastroesophageal junct...

                            Product Name : PT886

                            Product Type : Large molecule

                            Upfront Cash : Undisclosed

                            October 16, 2023

                            Lead Product(s) : PT886,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Merck & Co

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            08

                            Phanes Therapeutics

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                            Lead Product(s) : PT217

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Phanes Therapeutics Announces First Patient Dosed in Phase 1 Study of PT217 for Small Cell Lung Cancer and Oth...

                            Details : PT217 is a common light chain bispecific antibody discovered through Phanes' research engine and was granted orphan drug designation (ODD) for the treatment of small cell lung cancer by the FDA last year.

                            Product Name : PT217

                            Product Type : Large molecule

                            Upfront Cash : Not Applicable

                            September 07, 2023

                            Lead Product(s) : PT217

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Phanes Therapeutics

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                            SCOPE Summit
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                            Lead Product(s) : PT886

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Phanes Therapeutics Announces First Patient Dosed in Phase 1 Study of PT886 for Advanced Gastric, Gastroesopha...

                            Details : PT886 directly kills tumor cells via both the ADCP activity of macrophages and ADCC activity of NK cells, and by targeting both claudin 18.2 and CD47 overexpressed on the surface of tumor cells, it broadens the tumor killing spectrum.

                            Product Name : PT886

                            Product Type : Large molecule

                            Upfront Cash : Not Applicable

                            March 20, 2023

                            Lead Product(s) : PT886

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            Phanes Therapeutics

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                            Lead Product(s) : Bispecific Antibody

                            Therapeutic Area : Oncology

                            Study Phase : Discovery

                            Sponsor : Xyphos Biosciences

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Phanes Therapeutics Entered Into A Research Collaboration With Xyphos Biosciences, Inc., An Astellas Company

                            Details : The collaboration will leverage Phanes’ proprietary technology platforms, PACbody and SPECpair, in the evaluation of cell therapies in oncology. The company has its proprietary technology platforms to develop novel biologics that address high unmet med...

                            Product Name : Undisclosed

                            Product Type : Large molecule

                            Upfront Cash : Undisclosed

                            March 06, 2023

                            Lead Product(s) : Bispecific Antibody

                            Therapeutic Area : Oncology

                            Highest Development Status : Discovery

                            Sponsor : Xyphos Biosciences

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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