Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Pramipexole Dihydrochloride,Rasagiline Mesylate
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Hepion Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Merger
Pharma Two B Announces Merger with Hepion and $11.5M Private Placement
Details : Through the merger, the company will operate under Pharma Two B and also advance P2B001 (Pramipexole+Rasagiline), an easy-to-use therapeutic approach, that is designed to address PD.
Brand Name : P2B001
Molecule Type : Small molecule
Upfront Cash : Undisclosed
July 22, 2024
Lead Product(s) : Pramipexole Dihydrochloride,Rasagiline Mesylate
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Hepion Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Merger
Lead Product(s) : Pramipexole Dihydrochloride,Rasagiline Mesylate
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : P2B001 showed superior efficacy to each of its individual components in the trial and comparable efficacy to marketed doses of Pramipexole ER, but with reduced adverse events related to dopaminergic side effects and sleepiness, and with less worsening on...
Brand Name : P2B001
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 15, 2022
Lead Product(s) : Pramipexole Dihydrochloride,Rasagiline Mesylate
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Pramipexole Dihydrochloride,Rasagiline Mesylate
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Results demonstrated that P2B001, a combination of dopamine agonist, pramipexole, and MAO-B inhibitor, rasagiline has symptomatic benefits comparable to higher doses of marketed pramipexole ER, yet with less dopaminergic side effects and significantly le...
Brand Name : P2B001
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 05, 2022
Lead Product(s) : Pramipexole Dihydrochloride,Rasagiline Mesylate
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Pramipexole Dihydrochloride,Rasagiline Mesylate
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Results demonstrate P2B001 (pramipexole) distinctive combination of efficacy and enhanced safety, supporting its potential as a first-line treatment option for people with early PD.
Brand Name : P2B001
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 20, 2022
Lead Product(s) : Pramipexole Dihydrochloride,Rasagiline Mesylate
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Pramipexole Dihydrochloride,Rasagiline Mesylate
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Myung In Pharm
Deal Size : $5.0 million
Deal Type : Licensing Agreement
Details : Under the terms of the agreement, Myung In Pharm will seek regulatory approval for P2B001 in South Korea and will manufacture, commercialize and distribute P2B001 in the region.
Brand Name : P2B001
Molecule Type : Small molecule
Upfront Cash : Undisclosed
November 18, 2021
Lead Product(s) : Pramipexole Dihydrochloride,Rasagiline Mesylate
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Myung In Pharm
Deal Size : $5.0 million
Deal Type : Licensing Agreement
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