Lead Product(s) : HOPO-101
Therapeutic Area : Pharmacology/Toxicology
Study Phase : Phase I
Sponsor : BARDA
Deal Size : $226.0 million
Deal Type : Funding
HOPO Awarded Up to $226 Million from BARDA for Development of its Oral Decorporation Agent
Details : The funds will be used to advance development of the drug candidate HOPO-101 as a possible treatment for lead poisoning.
Brand Name : HOPO 14-1
Molecule Type : Small molecule
Upfront Cash : Undisclosed
October 28, 2024
Lead Product(s) : HOPO-101
Therapeutic Area : Pharmacology/Toxicology
Highest Development Status : Phase I
Sponsor : BARDA
Deal Size : $226.0 million
Deal Type : Funding
Lead Product(s) : RXRG001
Therapeutic Area : Pharmacology/Toxicology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
RiboX IND Clearance for RXRG001, First Circular RNA Therapy
Details : RXRG001 is the first-ever circular RNA therapy candidate, which is currently being evaluated for the treatment of radiation-induced xerostomia and hyposalivation.
Brand Name : RXRG001
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 25, 2024
Lead Product(s) : RXRG001
Therapeutic Area : Pharmacology/Toxicology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Opaganib
Therapeutic Area : Pharmacology/Toxicology
Study Phase : Preclinical
Sponsor : Duke University School
Deal Size : Undisclosed
Deal Type : Collaboration
RedHill Collaborates with U.S. Academic Center on Opaganib for Phosgene Injury
Details : The collaboration is designed to test ABC294640 (opaganib), a first-in-class, orally administered SPHK2 selective inhibitor, as a potential medical countermeasure to treat phosgene inhalation injury.
Brand Name : Yeliva
Molecule Type : Small molecule
Upfront Cash : Undisclosed
October 22, 2024
Lead Product(s) : Opaganib
Therapeutic Area : Pharmacology/Toxicology
Highest Development Status : Preclinical
Sponsor : Duke University School
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Pyridostigmine
Therapeutic Area : Pharmacology/Toxicology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Amneal Gains FDA Nod for Pyridostigmine Bromide Extended-Release Tablets
Details : Pyridostigmine Bromide, is a cholinesterase inhibitor small molecule drug administered orally for soman nerve agent poisoning in adults.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 21, 2024
Lead Product(s) : Pyridostigmine
Therapeutic Area : Pharmacology/Toxicology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Deferoxamine Mesylate
Therapeutic Area : Pharmacology/Toxicology
Study Phase : Approved
Sponsor : Mitem Pharma
Deal Size : Undisclosed
Deal Type : Acquisition
MITEM Pharma Acquires DESFERAL® Rights Backed by TECHLIFE CAPITAL, MACSF
Details : Mitem acquires Desfera (deferoxamine mesylate) products from Novartis. It is indicated for treating iron overload, and forex, following blood transfusions necessary for treating beta-thalassemia.
Brand Name : Desfera
Molecule Type : Small molecule
Upfront Cash : Undisclosed
September 25, 2024
Lead Product(s) : Deferoxamine Mesylate
Therapeutic Area : Pharmacology/Toxicology
Highest Development Status : Approved
Sponsor : Mitem Pharma
Deal Size : Undisclosed
Deal Type : Acquisition
Lead Product(s) : Patiromer Sorbitex Calcium
Therapeutic Area : Pharmacology/Toxicology
Study Phase : Approved
Sponsor : CSL Vifor
Deal Size : Not Applicable
Deal Type : Not Applicable
Veltassa® (patiromer) Approved in Japan For The Treatment of Adults with Hyperkalemia
Details : Veltassa (patiromer sorbitex calcium) is a potassium binder indicated for the treatment of hyperkalemia in adults and pediatric patients ages 12 years and older.
Brand Name : Veltassa
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 23, 2024
Lead Product(s) : Patiromer Sorbitex Calcium
Therapeutic Area : Pharmacology/Toxicology
Highest Development Status : Approved
Sponsor : CSL Vifor
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Selonabant
Therapeutic Area : Pharmacology/Toxicology
Study Phase : Phase II
Sponsor : National Institutes of Health
Deal Size : $1.9 million
Deal Type : Funding
Anebulo Pharmaceuticals Awarded NIDA Grant for Acute Cannabis-Induced Toxic Effects
Details : The funding aims to support the development of ANEB-001 (selonabant) for the potential use as an emergency treatment of acute cannabis-induced toxicities, including cannabis-induced CNS depression.
Brand Name : ANEB-001
Molecule Type : Small molecule
Upfront Cash : Undisclosed
July 22, 2024
Lead Product(s) : Selonabant
Therapeutic Area : Pharmacology/Toxicology
Highest Development Status : Phase II
Sponsor : National Institutes of Health
Deal Size : $1.9 million
Deal Type : Funding
Lead Product(s) : Glucarpidase
Therapeutic Area : Pharmacology/Toxicology
Study Phase : Approved
Sponsor : SERB Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Agreement
M8 Pharmaceuticals Signs Exclusive Agreement with SERB to Bring Voraxaze® to Latin America
Details : M8 will register, market and commercialize SERB's supportive oncology product Voraxaze (glucarpidase), a carboxypeptidase that reduces toxic plasma methotrexate concentration, in Latin America.
Brand Name : Voraxaze
Molecule Type : Small molecule
Upfront Cash : Undisclosed
March 20, 2024
Lead Product(s) : Glucarpidase
Therapeutic Area : Pharmacology/Toxicology
Highest Development Status : Approved
Sponsor : SERB Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Atropine,Pralidoxime Chloride
Therapeutic Area : Pharmacology/Toxicology
Study Phase : Approved
Sponsor : ASPR
Deal Size : $9.9 million
Deal Type : Agreement
Details : Under the agreement, Meridian will supply DuoDote to the Administration for Strategic Preparedness and Response within the United States. DuoDote® is an FDA-approved dual-chamber autoinjector (atropine and pralidoxime chloride) chemical nerve agent anti...
Brand Name : DuoDote
Molecule Type : Small molecule
Upfront Cash : Undisclosed
November 14, 2023
Lead Product(s) : Atropine,Pralidoxime Chloride
Therapeutic Area : Pharmacology/Toxicology
Highest Development Status : Approved
Sponsor : ASPR
Deal Size : $9.9 million
Deal Type : Agreement
Lead Product(s) : Edetate Calcium Disodium
Therapeutic Area : Pharmacology/Toxicology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Edetate calcium disodium for injection is a prescription medicine, used for the reduction of blood levels and depot stores of lead in lead poisoning (acute and chronic) and lead encephalopathy, in both pediatric populations and adults.
Brand Name : Edetate Calcium Disodium-Generic
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 10, 2023
Lead Product(s) : Edetate Calcium Disodium
Therapeutic Area : Pharmacology/Toxicology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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