Lead Product(s) : GP1681
Therapeutic Area : Pharmacology/Toxicology
Study Phase : Phase I/ Phase II
Sponsor : CytoAgents
Deal Size : Undisclosed
Deal Type : Collaboration
Quotient Sciences and CytoAgents Accelerate Potential Treatment for COVID-19 Cytokine Storm
Details : The collaboration aims to focus on the development of GP1681 (CTO1681), which is a small molecule inhibitor of cytokine release targeting the NF-kB signaling pathway via the activation of the EP4 receptor. It is under development for treatment of cytokin...
Product Name : GP1681
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
April 28, 2020
Lead Product(s) : GP1681
Therapeutic Area : Pharmacology/Toxicology
Highest Development Status : Phase I/ Phase II
Sponsor : CytoAgents
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : CTO1681
Therapeutic Area : Pharmacology/Toxicology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : CTO1681 cell therapy, prevents and treats Cytokine Release Syndrome by targeting the NF-kB signaling pathway via the activation of the EP4 receptor, which reduces NF-kB signaling.
Product Name : CTO1681
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 17, 2023
Lead Product(s) : CTO1681
Therapeutic Area : Pharmacology/Toxicology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Lenzilumab
Therapeutic Area : Pharmacology/Toxicology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The patent covers the use of lenzilumab to prevent or treat cytokine release syndrome (CRS), neurotoxicity and otherwise inhibit or reduce incidence or severity of CAR-T-related toxicities in patients undergoing CAR-T cell therapy.
Product Name : Humaneered
Product Type : Antibody
Upfront Cash : Inapplicable
December 28, 2020
Lead Product(s) : Lenzilumab
Therapeutic Area : Pharmacology/Toxicology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable