[{"orgOrder":0,"company":"Ocuphire Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Phentolamine Mesylate","moa":"Adrenergic-alpha-1\/2 receptor","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Ocuphire Pharma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Ocuphire Pharma \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Ocuphire Pharma \/ Inapplicable"},{"orgOrder":0,"company":"Opus Genetics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Phentolamine Mesylate","moa":"Adrenergic-alpha-1\/2 receptor","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Opus Genetics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Opus Genetics \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Opus Genetics \/ Inapplicable"},{"orgOrder":0,"company":"Viatris","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Phentolamine Mesylate","moa":"Adrenergic-alpha-1\/2 receptor","graph1":"Ophthalmology","graph2":"Approved FDF","graph3":"Viatris","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Viatris \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Viatris \/ Inapplicable"},{"orgOrder":0,"company":"Ocuphire Pharma","sponsor":"Viatris","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Phentolamine Mesylate","moa":"Adrenergic-alpha-1\/2 receptor","graph1":"Ophthalmology","graph2":"Approved FDF","graph3":"Ocuphire Pharma","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Ocuphire Pharma \/ Viatris","highestDevelopmentStatusID":"15","companyTruncated":"Ocuphire Pharma \/ Viatris"},{"orgOrder":0,"company":"Ocuphire Pharma","sponsor":"FamyGen Life Sciences","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Licensing Agreement","leadProduct":"Phentolamine Mesylate","moa":"Adrenergic-alpha-1\/2 receptor","graph1":"Ophthalmology","graph2":"Approved FDF","graph3":"Ocuphire Pharma","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Ocuphire Pharma \/ FamyGen Life Sciences","highestDevelopmentStatusID":"15","companyTruncated":"Ocuphire Pharma \/ FamyGen Life Sciences"},{"orgOrder":0,"company":"Ocuphire Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Phentolamine Mesylate","moa":"Adrenergic-alpha-1\/2 receptor","graph1":"Ophthalmology","graph2":"Approved FDF","graph3":"Ocuphire Pharma","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Ocuphire Pharma \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Ocuphire Pharma \/ Inapplicable"},{"orgOrder":0,"company":"Ocuphire Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Phentolamine Mesylate","moa":"Adrenergic-alpha-1\/2 receptor","graph1":"Ophthalmology","graph2":"Approved FDF","graph3":"Ocuphire Pharma","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Ocuphire Pharma \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Ocuphire Pharma \/ Inapplicable"},{"orgOrder":0,"company":"Ocuphire Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Phentolamine Mesylate","moa":"Adrenergic-alpha-1\/2 receptor","graph1":"Ophthalmology","graph2":"Approved FDF","graph3":"Ocuphire Pharma","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Ocuphire Pharma \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Ocuphire Pharma \/ Inapplicable"},{"orgOrder":0,"company":"Ocuphire Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Phentolamine Mesylate","moa":"Adrenergic-alpha-1\/2 receptor","graph1":"Ophthalmology","graph2":"Approved FDF","graph3":"Ocuphire Pharma","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Ocuphire Pharma \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Ocuphire Pharma \/ Inapplicable"},{"orgOrder":0,"company":"Ocuphire Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Phentolamine Mesylate","moa":"Adrenergic-alpha-1\/2 receptor","graph1":"Ophthalmology","graph2":"Approved FDF","graph3":"Ocuphire Pharma","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Ocuphire Pharma \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Ocuphire Pharma \/ Inapplicable"},{"orgOrder":0,"company":"Ocuphire Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Phentolamine Mesylate","moa":"Adrenergic-alpha-1\/2 receptor","graph1":"Ophthalmology","graph2":"Approved FDF","graph3":"Ocuphire Pharma","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Ocuphire Pharma \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Ocuphire Pharma \/ Inapplicable"},{"orgOrder":0,"company":"Ocuphire Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Phentolamine Mesylate","moa":"Adrenergic-alpha-1\/2 receptor","graph1":"Ophthalmology","graph2":"Approved FDF","graph3":"Ocuphire Pharma","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Ocuphire Pharma \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Ocuphire Pharma \/ Inapplicable"},{"orgOrder":0,"company":"Ocuphire Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Phentolamine Mesylate","moa":"Adrenergic-alpha-1\/2 receptor","graph1":"Ophthalmology","graph2":"Approved FDF","graph3":"Ocuphire Pharma","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Ocuphire Pharma \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Ocuphire Pharma \/ Inapplicable"},{"orgOrder":0,"company":"Ocuphire Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Phentolamine Mesylate","moa":"Adrenergic-alpha-1\/2 receptor","graph1":"Ophthalmology","graph2":"Approved FDF","graph3":"Ocuphire Pharma","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Ocuphire Pharma \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Ocuphire Pharma \/ Inapplicable"},{"orgOrder":0,"company":"Ocuphire Pharma","sponsor":"Oculos Development Services","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Phentolamine Mesylate","moa":"Adrenergic-alpha-1\/2 receptor","graph1":"Ophthalmology","graph2":"Approved FDF","graph3":"Ocuphire Pharma","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Ocuphire Pharma \/ Oculos Development Services","highestDevelopmentStatusID":"15","companyTruncated":"Ocuphire Pharma \/ Oculos Development Services"},{"orgOrder":0,"company":"Ocuphire Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Phentolamine Mesylate","moa":"Adrenergic-alpha-1\/2 receptor","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Ocuphire Pharma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Ocuphire Pharma \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Ocuphire Pharma \/ Inapplicable"},{"orgOrder":0,"company":"Ocuphire Pharma","sponsor":"Rexahn Pharmaceuticals Inc","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Merger","leadProduct":"Phentolamine Mesylate","moa":"Adrenergic-alpha-1\/2 receptor","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Ocuphire Pharma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Ocuphire Pharma \/ Rexahn Pharmaceuticals Inc","highestDevelopmentStatusID":"10","companyTruncated":"Ocuphire Pharma \/ Rexahn Pharmaceuticals Inc"},{"orgOrder":0,"company":"Ocuphire Pharma","sponsor":"National Institutes of Health","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Funding","leadProduct":"Phentolamine Mesylate","moa":"Adrenergic-alpha-1\/2 receptor","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Ocuphire Pharma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Ocuphire Pharma \/ National Institutes of Health","highestDevelopmentStatusID":"10","companyTruncated":"Ocuphire Pharma \/ National Institutes of Health"},{"orgOrder":0,"company":"Ocuphire Pharma","sponsor":"American Society of Ophthalmic Administrator","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Partnership","leadProduct":"Phentolamine Mesylate","moa":"Adrenergic-alpha-1\/2 receptor","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Ocuphire Pharma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Ocuphire Pharma \/ American Society of Ophthalmic Administrator","highestDevelopmentStatusID":"10","companyTruncated":"Ocuphire Pharma \/ American Society of Ophthalmic Administrator"},{"orgOrder":0,"company":"Ocuphire Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Phentolamine Mesylate","moa":"Adrenergic-alpha-1\/2 receptor","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Ocuphire Pharma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Ocuphire Pharma \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Ocuphire Pharma \/ Inapplicable"},{"orgOrder":0,"company":"Ocuphire Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Phentolamine Mesylate","moa":"||Adrenergic-alpha-1\/2 receptor","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Ocuphire Pharma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Ocuphire Pharma \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Ocuphire Pharma \/ Inapplicable"},{"orgOrder":0,"company":"Ocuphire Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Phentolamine Mesylate","moa":"||Adrenergic-alpha-1\/2 receptor","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Ocuphire Pharma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Ocuphire Pharma \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Ocuphire Pharma \/ Inapplicable"},{"orgOrder":0,"company":"Ocuphire Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small 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Solution","sponsorNew":"Ocuphire Pharma \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Ocuphire Pharma \/ Inapplicable"},{"orgOrder":0,"company":"Ocuphire Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Phentolamine Mesylate","moa":"||Adrenergic-alpha-1\/2 receptor","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Ocuphire Pharma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Ocuphire Pharma \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Ocuphire Pharma \/ Inapplicable"},{"orgOrder":0,"company":"Ocuphire Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Phentolamine Mesylate","moa":"Adrenergic-alpha-1\/2 receptor","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Ocuphire Pharma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Ocuphire Pharma \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Ocuphire Pharma \/ Inapplicable"},{"orgOrder":0,"company":"Ocuphire Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Phentolamine Mesylate","moa":"||Adrenergic-alpha-1\/2 receptor","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Ocuphire Pharma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Ocuphire Pharma \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Ocuphire Pharma \/ Inapplicable"},{"orgOrder":0,"company":"Ocuphire Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Phentolamine Mesylate","moa":"Adrenergic-alpha-1\/2 receptor","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Ocuphire Pharma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Ocuphire Pharma \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Ocuphire Pharma \/ Inapplicable"},{"orgOrder":0,"company":"Opus Genetics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Phentolamine Mesylate","moa":"Adrenergic-alpha-1\/2 receptor","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Opus Genetics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Opus Genetics \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Opus Genetics \/ Inapplicable"}]

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                          01

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : Nyxol (phentolamine ophthalmic solution 0.75%) is being evaluated for the treatment in patients with dim light disturbances and decreased mesopic vision.

                          Product Name : Nyxol

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          March 21, 2025

                          Lead Product(s) : Phentolamine Mesylate

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : Nyxol (phentolamine mesylate) an alpha1/2 adrenergic receptor inhibitor, is being investigated for decreased visual acuity under low light conditions following keratorefractive surgery.

                          Product Name : Nyxol

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          February 26, 2025

                          Lead Product(s) : Phentolamine Mesylate

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : Nyxol (phentolamine mesylate ophthalmic solution) is an alpha1/2 adrenergic receptor inhibitor being investigated in Phase 3 for decreased visual acuity under low light after keratorefractive surgery.

                          Product Name : Nyxol

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          November 04, 2024

                          Lead Product(s) : Phentolamine Mesylate

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : Nyxol (phentolamine ophthalmic solution) is an adrenergic receptor antagonist. It is being evaluated for the treatment Presbyopia.

                          Product Name : Nyxol

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          May 09, 2024

                          Lead Product(s) : Phentolamine Mesylate

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : Nyxol (phentolamine ophthalmic solution) is anadrenergic receptor antagonist. It is being evaluated in phase 3 clinical trials for decreased visual acuity under dim (mesopic) light conditions.

                          Product Name : Nyxol

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          April 01, 2024

                          Lead Product(s) : Phentolamine Mesylate

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : Ryzumvi (phentolamine mesylate) is an alpha adrenergic blocker indicated for treating pharmacologically-induced mydriasis produced by adrenergic agonists or parasympatholytic agents like tropicamide.

                          Product Name : Ryzumvi

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          January 04, 2024

                          Lead Product(s) : Phentolamine Mesylate

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : Ryzumvi (phentolamine ophthalmic solution) 0.75% is a preservative-free ophthalmic solution and a nonselective alpha adrenergic antagonist, which is investigated for Pharmacologically-Induced Mydriasis Produced by Adrenergic Agonists.

                          Product Name : Nyxol

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          September 27, 2023

                          Lead Product(s) : Phentolamine Mesylate

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Approved FDF

                          Sponsor : Viatris

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : Nyxol® is a preservative-free ophthalmic solution containing 0.75% phentolamine (or 1% phentolamine mesylate), a nonselective alpha adrenergic antagonist that inhibits the contraction of smooth muscle of the iris.

                          Product Name : Nyxol

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          September 01, 2023

                          Lead Product(s) : Phentolamine Mesylate,Pilocarpine Hydrochloride

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : Nyxol® is a preservative-free ophthalmic solution containing 0.75% phentolamine (or 1% phentolamine mesylate), a nonselective alpha adrenergic antagonist that inhibits the contraction of smooth muscle of the iris.

                          Product Name : Nyxol

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          February 13, 2023

                          Lead Product(s) : Phentolamine Mesylate

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : Nyxol® eye drops (0.75% phentolamine ophthalmic solution), is a once-daily, preservative-free eye drop formulation of phentolamine mesylate, a non-selective alpha-1 and alpha-2 adrenergic antagonist designed to reduce pupil size, and is being developed ...

                          Product Name : Nyxol

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          December 09, 2022

                          Lead Product(s) : Phentolamine Mesylate

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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