Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Tropicamide,Phenylephrine Hydrochloride
Therapeutic Area : Ophthalmology
Study Phase : Phase IV
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Eyenovia Provides Update on Mydcombi™ and Clobetasol Propionate Ophthalmic Suspension
Details : Mydcombi is FDA approved, first-in-class fixed-dose-combination product (tropicamide 1% and phenylephrine 2.5% ophthalmic spray) for pharmacologic mydriasis (eye dilation).
Brand Name : Mydcombi
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 25, 2024
Lead Product(s) : Tropicamide,Phenylephrine Hydrochloride
Therapeutic Area : Ophthalmology
Highest Development Status : Phase IV
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Phenylephrine Hydrochloride,Tropicamide
Therapeutic Area : Ophthalmology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Mydcombi is Eyenovia's USFDA approved, first-in-class fixed-dose-combination product (tropicamide 1% and phenylephrine 2.5% ophthalmic spray) for pharmacologic mydriasis (eye dilation).
Brand Name : Mydcombi
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 08, 2023
Lead Product(s) : Phenylephrine Hydrochloride,Tropicamide
Therapeutic Area : Ophthalmology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Phenylephrine Hydrochloride,Ketorolac Trometamol
Therapeutic Area : Ophthalmology
Study Phase : Approved
Sponsor : Rayner
Deal Size : $1,326 million
Deal Type : Divestment
Omeros Corporation Receives $200 Million Milestone Payment from Rayner Surgical
Details : Under the terms of the Agreement, the royalty rate applicable to U.S. net sales of OMIDRIA (phenylephrine) decreased from 50 percent to 30 percent of U.S. net sales following achievement of the Milestone Event.
Brand Name : Omidria
Molecule Type : Small molecule
Upfront Cash : $126.0 million
February 06, 2023
Lead Product(s) : Phenylephrine Hydrochloride,Ketorolac Trometamol
Therapeutic Area : Ophthalmology
Highest Development Status : Approved
Sponsor : Rayner
Deal Size : $1,326 million
Deal Type : Divestment
Lead Product(s) : Tropicamide,Phenylephrine Hydrochloride
Therapeutic Area : Ophthalmology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Mydcombi is Eyenovia's investigational, first-in-class fixed-dose-combination product (tropicamide 1% and phenylephrine 2.5% ophthalmic spray) for pharmacologic mydriasis (eye dilation).
Brand Name : Mydcombi
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 12, 2023
Lead Product(s) : Tropicamide,Phenylephrine Hydrochloride
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Tropicamide,Phenylephrine Hydrochloride
Therapeutic Area : Ophthalmology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Eyenovia Announces FDA Acceptance of New Drug Application for MydCombi™ for In-Office Pupil Dilation
Details : Mydcombi is Eyenovia's investigational, first-in-class fixed-dose-combination product (tropicamide 1% and phenylephrine 2.5% ophthalmic spray) for pharmacologic mydriasis (eye dilation).
Brand Name : Mydcombi
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 13, 2022
Lead Product(s) : Tropicamide,Phenylephrine Hydrochloride
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Tropicamide,Phenylephrine Hydrochloride
Therapeutic Area : Ophthalmology
Study Phase : Phase III
Sponsor : Avenue Venture Opportunities Fund
Deal Size : Undisclosed
Deal Type : Financing
Eyenovia Announces $15 Million Credit Facility with Avenue Venture Debt Fund
Details : The financing is intended to support manufacturing in anticipation of a MydCombi (tropicamide) launch and clinical supply for ongoing programs. Eyenovia is currently focused on the late-stage development of microdosed medications for mydriasis and myopia...
Brand Name : Mydcombi
Molecule Type : Small molecule
Upfront Cash : Undisclosed
November 29, 2022
Lead Product(s) : Tropicamide,Phenylephrine Hydrochloride
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Sponsor : Avenue Venture Opportunities Fund
Deal Size : Undisclosed
Deal Type : Financing
Lead Product(s) : Phenylephrine Hydrochloride,Ketorolac Trometamol
Therapeutic Area : Neurology
Study Phase : Approved
Sponsor : DRI Healthcare Acquisitions
Deal Size : $188.4 million
Deal Type : Agreement
Omeros Corporation Announces Royalty Monetization Transaction with DRI Healthcare Trust
Details : Under the Royalty Purchase Agreement, DRI is entitled to royalties on net sales of OMIDRIA (having phenylephrine) received between September 1, 2022 and December 31, 2030, subject to annual caps.
Brand Name : Omidria
Molecule Type : Small molecule
Upfront Cash : Undisclosed
October 03, 2022
Lead Product(s) : Phenylephrine Hydrochloride,Ketorolac Trometamol
Therapeutic Area : Neurology
Highest Development Status : Approved
Sponsor : DRI Healthcare Acquisitions
Deal Size : $188.4 million
Deal Type : Agreement
Lead Product(s) : Phenylephrine Hydrochloride
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Approved
Sponsor : Dr. Reddy\'s Laboratories
Deal Size : $50.0 million
Deal Type : Acquisition
Eton Pharmaceuticals Announces Sale of Hospital Products
Details : Under terms of the agreement, Dr Reddy’s purchased the Biorphen® (phenylephrine hydrochloride), Rezipres®, and Cysteine Hydrochloride products. Dr Reddy’s will immediately take ownership of Eton’s rights and interests in the products.
Brand Name : Biorphen
Molecule Type : Small molecule
Upfront Cash : Undisclosed
June 24, 2022
Lead Product(s) : Phenylephrine Hydrochloride
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Approved
Sponsor : Dr. Reddy\'s Laboratories
Deal Size : $50.0 million
Deal Type : Acquisition
Lead Product(s) : Tropicamide,Phenylephrine Hydrochloride
Therapeutic Area : Ophthalmology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Eyenovia Concludes Type A Meeting with FDA Related to MydCombi™ NDA Resubmission
Details : MydCombi™ has the potential to increase patient throughput at practicing offices by decreasing time spent eye dropping patients, eliminating time wasted waiting between drop instillations and ensuring more accurate drug delivery.
Brand Name : MydCombi
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 08, 2022
Lead Product(s) : Tropicamide,Phenylephrine Hydrochloride
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Phenylephrine Hydrochloride,Ketorolac Trometamol
Therapeutic Area : Ophthalmology
Study Phase : Approved
Sponsor : Rayner
Deal Size : $1,326 million
Deal Type : Divestment
Omeros Completes Sale of OMIDRIA® Franchise to Rayner Surgical
Details : As part of the agreement, Rayner will acquire the OMIDRIA (phenylephrine) commercial organization, including the OMIDRIA sales force. In addition, Rayner plans to expand the sales force in both the U.S. and ex-U.S.
Brand Name : Omidria
Molecule Type : Small molecule
Upfront Cash : $126.0 million
December 23, 2021
Lead Product(s) : Phenylephrine Hydrochloride,Ketorolac Trometamol
Therapeutic Area : Ophthalmology
Highest Development Status : Approved
Sponsor : Rayner
Deal Size : $1,326 million
Deal Type : Divestment
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